ZNF580 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006954Biological processinflammatory response
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0010595Biological processpositive regulation of endothelial cell migration
GO_0010628Biological processpositive regulation of gene expression
GO_0006935Biological processchemotaxis
GO_0001938Biological processpositive regulation of endothelial cell proliferation
GO_0032757Biological processpositive regulation of interleukin-8 production
GO_0002690Biological processpositive regulation of leukocyte chemotaxis
GO_0070301Biological processcellular response to hydrogen peroxide
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0046872Molecular functionmetal ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameZNF580
Protein nameZinc finger protein 580 (LDL-induced EC protein)
Zinc finger protein 580
Synonyms
DescriptionFUNCTION: Involved in the regulation of endothelial cell proliferation and migration. Mediates H(2)O(2)-induced leukocyte chemotaxis by elevating interleukin-8 production and may play a role in inflammation. May be involved in transcriptional regulation. .

AccessionsK7ENY2
ENST00000590190.1
ENST00000325333.10
K7ERU0
ENST00000592461.5
ENST00000545125.1
Q9UK33
ENST00000592881.1
ENST00000543039.2
K7EJ53