VPS37B | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	29 studies	27% ± 7%	Explore
B cell	20 studies	22% ± 5%	Explore
mast cell	16 studies	24% ± 6%	Explore
endothelial cell	14 studies	23% ± 7%	Explore
naive B cell	14 studies	23% ± 6%	Explore
T cell	13 studies	21% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	26% ± 8%	Explore
CD8-positive, alpha-beta T cell	13 studies	21% ± 5%	Explore
mature NK T cell	13 studies	21% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	28% ± 6%	Explore
epithelial cell	9 studies	34% ± 18%	Explore
gamma-delta T cell	9 studies	27% ± 10%	Explore
type I pneumocyte	8 studies	29% ± 7%	Explore
plasma cell	8 studies	31% ± 8%	Explore
mucosal invariant T cell	8 studies	23% ± 5%	Explore
basal cell	8 studies	26% ± 10%	Explore
CD4-positive, alpha-beta T cell	7 studies	20% ± 4%	Explore
memory B cell	7 studies	22% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	25% ± 6%	Explore
type II pneumocyte	6 studies	20% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	24% ± 8%	Explore
club cell	6 studies	25% ± 6%	Explore
ciliated cell	6 studies	30% ± 14%	Explore
plasmablast	5 studies	32% ± 15%	Explore
hematopoietic stem cell	5 studies	22% ± 7%	Explore
monocyte	5 studies	16% ± 1%	Explore
respiratory goblet cell	4 studies	23% ± 4%	Explore
squamous epithelial cell	4 studies	57% ± 18%	Explore
classical monocyte	4 studies	20% ± 5%	Explore
microglial cell	4 studies	20% ± 4%	Explore
secretory cell	4 studies	24% ± 7%	Explore
astrocyte	4 studies	19% ± 1%	Explore
goblet cell	4 studies	33% ± 22%	Explore
leukocyte	4 studies	22% ± 3%	Explore
hematopoietic precursor cell	3 studies	24% ± 9%	Explore
non-classical monocyte	3 studies	20% ± 5%	Explore
myeloid cell	3 studies	17% ± 1%	Explore
immature B cell	3 studies	20% ± 3%	Explore
lymphocyte	3 studies	28% ± 7%	Explore
innate lymphoid cell	3 studies	24% ± 6%	Explore
endothelial cell of lymphatic vessel	3 studies	16% ± 1%	Explore
endothelial cell of vascular tree	3 studies	21% ± 4%	Explore
glutamatergic neuron	3 studies	40% ± 16%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	36% ± 15%	Explore
macrophage	3 studies	17% ± 1%	Explore
mucus secreting cell	3 studies	21% ± 2%	Explore
oligodendrocyte	3 studies	17% ± 1%	Explore
pericyte	3 studies	20% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	7 studies	22% ± 5%	Explore
peripheral blood	5 studies	22% ± 5%	Explore
liver	5 studies	17% ± 2%	Explore
brain	4 studies	28% ± 11%	Explore
intestine	3 studies	16% ± 1%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3398.67	1445 / 1445	100%	30.30	183 / 183
uterus	100%	1293.98	170 / 170	100%	28.71	459 / 459
prostate	100%	2285.57	245 / 245	100%	21.79	501 / 502
pancreas	100%	1524.03	327 / 328	100%	33.66	178 / 178
thymus	100%	3338.85	653 / 653	100%	22.28	603 / 605
stomach	100%	2977.20	359 / 359	100%	29.53	285 / 286
bladder	100%	1705.71	21 / 21	100%	29.57	502 / 504
intestine	100%	2358.35	966 / 966	99%	34.70	524 / 527
skin	100%	2212.83	1809 / 1809	99%	25.72	469 / 472
lung	100%	3117.23	578 / 578	99%	24.24	1145 / 1155
ovary	100%	1545.94	180 / 180	99%	19.26	424 / 430
brain	100%	1381.31	2630 / 2642	99%	25.92	697 / 705
breast	100%	2131.43	459 / 459	98%	16.94	1099 / 1118
kidney	100%	2281.47	89 / 89	96%	13.25	861 / 901
adrenal gland	100%	2684.17	258 / 258	90%	10.99	208 / 230
liver	82%	577.23	186 / 226	32%	3.93	129 / 406
eye	0%	0	0 / 0	100%	15.00	80 / 80
spleen	100%	3813.83	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	26.74	45 / 45
ureter	0%	0	0 / 0	100%	68.87	1 / 1
adipose	100%	1928.45	1202 / 1204	0%	0	0 / 0
blood vessel	100%	1522.31	1329 / 1335	0%	0	0 / 0
heart	99%	1297.46	852 / 861	0%	0	0 / 0
peripheral blood	99%	3771.21	917 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	83%	10.70	24 / 29
muscle	53%	302.16	425 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006623	Biological process	protein targeting to vacuole
GO_0039702	Biological process	viral budding via host ESCRT complex
GO_0036258	Biological process	multivesicular body assembly
GO_0016236	Biological process	macroautophagy
GO_0006612	Biological process	protein targeting to membrane
GO_0043162	Biological process	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO_0090148	Biological process	membrane fission
GO_0019076	Biological process	viral release from host cell
GO_1903774	Biological process	positive regulation of viral budding via host ESCRT complex
GO_0043328	Biological process	protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO_0030496	Cellular component	midbody
GO_0031902	Cellular component	late endosome membrane
GO_0005886	Cellular component	plasma membrane
GO_0070062	Cellular component	extracellular exosome
GO_0000813	Cellular component	ESCRT I complex
GO_0005737	Cellular component	cytoplasm
GO_0010008	Cellular component	endosome membrane
GO_0005768	Cellular component	endosome
GO_0048306	Molecular function	calcium-dependent protein binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	VPS37B
Protein name	VPS37B subunit of ESCRT-I Vacuolar protein sorting-associated protein 37B (hVps37B) (ESCRT-I complex subunit VPS37B)
Synonyms
Description	FUNCTION: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. . FUNCTION: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. . FUNCTION: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. .
Accessions	ENST00000267202.7 Q9H9H4 F5H4M0 ENST00000535765.5 F5H1F6 ENST00000371248.3

VPS37B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review