Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 23 studies | 46% ± 15% | |
| astrocyte | 18 studies | 48% ± 20% | |
| oligodendrocyte | 15 studies | 44% ± 17% | |
| microglial cell | 15 studies | 57% ± 16% | |
| macrophage | 13 studies | 50% ± 20% | |
| oligodendrocyte precursor cell | 13 studies | 52% ± 16% | |
| fibroblast | 13 studies | 51% ± 16% | |
| glutamatergic neuron | 12 studies | 59% ± 24% | |
| GABAergic neuron | 11 studies | 58% ± 24% | |
| pericyte | 10 studies | 43% ± 14% | |
| smooth muscle cell | 10 studies | 42% ± 14% | |
| adipocyte | 9 studies | 55% ± 15% | |
| mast cell | 9 studies | 34% ± 14% | |
| epithelial cell | 7 studies | 41% ± 22% | |
| B cell | 7 studies | 42% ± 13% | |
| mesothelial cell | 7 studies | 43% ± 17% | |
| endothelial cell of lymphatic vessel | 7 studies | 45% ± 12% | |
| neuron | 6 studies | 54% ± 25% | |
| interneuron | 6 studies | 68% ± 20% | |
| dendritic cell | 6 studies | 46% ± 17% | |
| basal cell | 6 studies | 44% ± 25% | |
| ciliated cell | 6 studies | 33% ± 16% | |
| T cell | 6 studies | 41% ± 12% | |
| myeloid cell | 6 studies | 46% ± 14% | |
| cardiac muscle cell | 5 studies | 48% ± 13% | |
| monocyte | 5 studies | 58% ± 6% | |
| type I pneumocyte | 5 studies | 55% ± 8% | |
| type II pneumocyte | 5 studies | 40% ± 7% | |
| granule cell | 4 studies | 49% ± 8% | |
| plasma cell | 4 studies | 39% ± 13% | |
| CD4-positive, alpha-beta T cell | 4 studies | 37% ± 11% | |
| Mueller cell | 4 studies | 44% ± 20% | |
| amacrine cell | 4 studies | 45% ± 18% | |
| retina horizontal cell | 4 studies | 46% ± 21% | |
| retinal cone cell | 4 studies | 50% ± 20% | |
| retinal rod cell | 4 studies | 45% ± 12% | |
| club cell | 4 studies | 44% ± 10% | |
| natural killer cell | 4 studies | 46% ± 9% | |
| leukocyte | 4 studies | 61% ± 5% | |
| hepatic stellate cell | 3 studies | 43% ± 20% | |
| differentiation-committed oligodendrocyte precursor | 3 studies | 50% ± 5% | |
| GABAergic interneuron | 3 studies | 60% ± 3% | |
| glial cell | 3 studies | 39% ± 9% | |
| progenitor cell | 3 studies | 49% ± 0% | |
| CD8-positive, alpha-beta T cell | 3 studies | 39% ± 8% | |
| vein endothelial cell | 3 studies | 38% ± 12% | |
| GABAergic amacrine cell | 3 studies | 45% ± 18% | |
| glycinergic amacrine cell | 3 studies | 45% ± 15% | |
| retinal ganglion cell | 3 studies | 64% ± 18% | |
| endothelial cell of vascular tree | 3 studies | 42% ± 14% | |
| hepatocyte | 3 studies | 65% ± 19% | |
| retinal pigment epithelial cell | 3 studies | 48% ± 27% | |
| abnormal cell | 3 studies | 34% ± 24% | |
| ependymal cell | 3 studies | 55% ± 17% | |
| alveolar macrophage | 3 studies | 62% ± 11% | |
| capillary endothelial cell | 3 studies | 39% ± 4% | |
| myofibroblast cell | 3 studies | 46% ± 20% | |
| respiratory goblet cell | 3 studies | 49% ± 16% | |
| lymphocyte | 3 studies | 51% ± 15% | |
| muscle cell | 3 studies | 41% ± 21% | |
| goblet cell | 3 studies | 48% ± 33% | |
| mural cell | 3 studies | 50% ± 6% | |
| mucus secreting cell | 3 studies | 40% ± 3% | |
| regulatory T cell | 3 studies | 41% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 3207.14 | 1445 / 1445 | 100% | 14.57 | 183 / 183 |
| breast | 100% | 3564.14 | 459 / 459 | 99% | 17.13 | 1108 / 1118 |
| lung | 100% | 3116.67 | 578 / 578 | 99% | 9.50 | 1141 / 1155 |
| prostate | 100% | 3566.19 | 245 / 245 | 98% | 13.84 | 493 / 502 |
| stomach | 100% | 2432.70 | 359 / 359 | 98% | 9.26 | 280 / 286 |
| brain | 98% | 1855.58 | 2602 / 2642 | 99% | 11.86 | 699 / 705 |
| intestine | 100% | 3476.13 | 966 / 966 | 97% | 6.86 | 510 / 527 |
| bladder | 100% | 3616.43 | 21 / 21 | 96% | 7.29 | 484 / 504 |
| thymus | 100% | 3182.68 | 653 / 653 | 96% | 7.25 | 579 / 605 |
| pancreas | 99% | 1509.51 | 326 / 328 | 96% | 7.93 | 171 / 178 |
| skin | 100% | 3809.54 | 1809 / 1809 | 94% | 8.66 | 444 / 472 |
| ovary | 100% | 5187.66 | 180 / 180 | 94% | 6.10 | 403 / 430 |
| uterus | 100% | 5859.94 | 170 / 170 | 94% | 7.29 | 430 / 459 |
| kidney | 100% | 1845.80 | 89 / 89 | 93% | 8.25 | 836 / 901 |
| adrenal gland | 100% | 3226.04 | 258 / 258 | 89% | 5.41 | 205 / 230 |
| liver | 99% | 987.62 | 224 / 226 | 80% | 4.06 | 324 / 406 |
| adipose | 100% | 3562.15 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 3829.58 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2845.83 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 2.42 | 1 / 1 |
| muscle | 99% | 1695.92 | 798 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 7.85 | 44 / 45 |
| peripheral blood | 96% | 2339.91 | 894 / 929 | 0% | 0 | 0 / 0 |
| heart | 95% | 1518.23 | 820 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 93% | 6.78 | 27 / 29 |
| eye | 0% | 0 | 0 / 0 | 83% | 6.28 | 66 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0016192 | Biological process | vesicle-mediated transport |
| GO_0007030 | Biological process | Golgi organization |
| GO_0032458 | Biological process | slow endocytic recycling |
| GO_0036438 | Biological process | maintenance of lens transparency |
| GO_0001675 | Biological process | acrosome assembly |
| GO_0060612 | Biological process | adipose tissue development |
| GO_0007399 | Biological process | nervous system development |
| GO_0006869 | Biological process | lipid transport |
| GO_0007417 | Biological process | central nervous system development |
| GO_0031175 | Biological process | neuron projection development |
| GO_0033116 | Cellular component | endoplasmic reticulum-Golgi intermediate compartment membrane |
| GO_0002080 | Cellular component | acrosomal membrane |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0031901 | Cellular component | early endosome membrane |
| GO_0055038 | Cellular component | recycling endosome membrane |
| GO_0005765 | Cellular component | lysosomal membrane |
| GO_0032266 | Molecular function | phosphatidylinositol-3-phosphate binding |
| Gene name | VPS13B |
| Protein name | Vacuolar protein sorting 13 homolog B Alternative protein VPS13B VPS13B protein Intermembrane lipid transfer protein VPS13B (Cohen syndrome protein 1) (Vacuolar protein sorting-associated protein 13B) |
| Synonyms | CHS1 KIAA0532 COH1 |
| Description | FUNCTION: Mediates the transfer of lipids between membranes at organelle contact sites (By similarity). Binds phosphatidylinositol 3-phosphate (By similarity). Functions as a tethering factor in the slow endocytic recycling pathway, to assist traffic between early and recycling endosomes . Involved in the transport of proacrosomal vesicles to the nuclear dense lamina (NDL) during spermatid development (By similarity). Plays a role in the assembly of the Golgi apparatus, possibly by mediating trafficking to the Golgi membrane . Plays a role in the development of the nervous system, and may be required for neuron projection development . May also play a role during adipose tissue development . Required for maintenance of the ocular lens (By similarity). . |
| Accessions | A0A8C8KE22 A0A804HKG9 A0A804HJ62 Q8N509 ENST00000682153.1 ENST00000441350.2 [Q7Z7G8-5] ENST00000358544.7 [Q7Z7G8-1] ENST00000357162.7 [Q7Z7G8-2] Q8WW67 H0YB72 ENST00000496144.5 [Q7Z7G8-3] Q7Z7G8 A0A804HL73 ENST00000521559.1 ENST00000683334.1 ENST00000355155.6 L8EAQ4 ENST00000682234.1 |