Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 18 studies | 30% ± 15% | |
B cell | 14 studies | 21% ± 5% | |
fibroblast | 12 studies | 25% ± 9% | |
mast cell | 11 studies | 25% ± 6% | |
plasma cell | 11 studies | 33% ± 16% | |
oligodendrocyte | 11 studies | 37% ± 14% | |
natural killer cell | 10 studies | 18% ± 2% | |
glutamatergic neuron | 10 studies | 40% ± 26% | |
astrocyte | 10 studies | 30% ± 13% | |
regulatory T cell | 10 studies | 20% ± 2% | |
oligodendrocyte precursor cell | 9 studies | 31% ± 13% | |
microglial cell | 8 studies | 27% ± 9% | |
epithelial cell | 8 studies | 33% ± 16% | |
basal cell | 8 studies | 27% ± 14% | |
endothelial cell of lymphatic vessel | 7 studies | 28% ± 12% | |
plasmablast | 7 studies | 36% ± 19% | |
macrophage | 7 studies | 33% ± 8% | |
GABAergic neuron | 7 studies | 47% ± 20% | |
hematopoietic precursor cell | 6 studies | 25% ± 7% | |
classical monocyte | 6 studies | 24% ± 9% | |
neuron | 6 studies | 37% ± 14% | |
amacrine cell | 6 studies | 23% ± 9% | |
interneuron | 6 studies | 47% ± 23% | |
plasmacytoid dendritic cell | 6 studies | 21% ± 6% | |
adipocyte | 6 studies | 26% ± 5% | |
dendritic cell | 6 studies | 26% ± 9% | |
monocyte | 6 studies | 23% ± 9% | |
pericyte | 6 studies | 23% ± 7% | |
CD4-positive, alpha-beta T cell | 5 studies | 17% ± 0% | |
retinal bipolar neuron | 5 studies | 23% ± 4% | |
myeloid cell | 5 studies | 22% ± 2% | |
retina horizontal cell | 5 studies | 24% ± 8% | |
club cell | 5 studies | 19% ± 7% | |
smooth muscle cell | 5 studies | 21% ± 3% | |
CD8-positive, alpha-beta memory T cell | 5 studies | 17% ± 3% | |
memory B cell | 5 studies | 17% ± 1% | |
T cell | 4 studies | 20% ± 2% | |
non-classical monocyte | 4 studies | 19% ± 4% | |
granule cell | 4 studies | 24% ± 5% | |
CD16-negative, CD56-bright natural killer cell, human | 4 studies | 17% ± 1% | |
cardiac muscle cell | 4 studies | 18% ± 1% | |
ciliated cell | 4 studies | 26% ± 6% | |
lymphocyte | 4 studies | 32% ± 10% | |
type I pneumocyte | 4 studies | 21% ± 5% | |
type II pneumocyte | 4 studies | 20% ± 4% | |
CD8-positive, alpha-beta T cell | 4 studies | 17% ± 1% | |
myofibroblast cell | 4 studies | 22% ± 7% | |
gamma-delta T cell | 4 studies | 24% ± 11% | |
goblet cell | 4 studies | 27% ± 15% | |
GABAergic interneuron | 3 studies | 31% ± 5% | |
progenitor cell | 3 studies | 26% ± 4% | |
retinal ganglion cell | 3 studies | 28% ± 5% | |
effector memory CD8-positive, alpha-beta T cell | 3 studies | 17% ± 1% | |
ON-bipolar cell | 3 studies | 26% ± 10% | |
glycinergic amacrine cell | 3 studies | 21% ± 5% | |
rod bipolar cell | 3 studies | 39% ± 13% | |
respiratory goblet cell | 3 studies | 16% ± 0% | |
abnormal cell | 3 studies | 26% ± 10% | |
connective tissue cell | 3 studies | 19% ± 2% | |
granulocyte monocyte progenitor cell | 3 studies | 28% ± 13% | |
hematopoietic stem cell | 3 studies | 20% ± 3% | |
leukocyte | 3 studies | 23% ± 1% | |
transit amplifying cell | 3 studies | 39% ± 26% | |
erythroblast | 3 studies | 32% ± 13% | |
IgA plasma cell | 3 studies | 28% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 4285.38 | 21 / 21 | 100% | 20.08 | 504 / 504 |
breast | 100% | 4687.54 | 459 / 459 | 100% | 24.97 | 1118 / 1118 |
esophagus | 100% | 3965.55 | 1445 / 1445 | 100% | 20.70 | 183 / 183 |
lung | 100% | 4288.58 | 578 / 578 | 100% | 20.85 | 1155 / 1155 |
prostate | 100% | 4611.36 | 245 / 245 | 100% | 22.49 | 502 / 502 |
stomach | 100% | 3837.38 | 359 / 359 | 100% | 18.85 | 286 / 286 |
uterus | 100% | 4824.19 | 170 / 170 | 100% | 24.12 | 459 / 459 |
thymus | 100% | 5352.43 | 653 / 653 | 100% | 23.16 | 603 / 605 |
intestine | 100% | 4600.62 | 966 / 966 | 100% | 17.80 | 525 / 527 |
ovary | 100% | 5503.80 | 180 / 180 | 100% | 15.60 | 428 / 430 |
brain | 99% | 4264.84 | 2628 / 2642 | 100% | 18.98 | 705 / 705 |
pancreas | 100% | 2511.17 | 328 / 328 | 99% | 19.93 | 177 / 178 |
skin | 100% | 5027.15 | 1809 / 1809 | 99% | 41.56 | 469 / 472 |
kidney | 100% | 2809.92 | 89 / 89 | 98% | 15.80 | 885 / 901 |
adrenal gland | 100% | 8433.69 | 258 / 258 | 96% | 15.21 | 221 / 230 |
liver | 100% | 2286.47 | 226 / 226 | 93% | 8.93 | 379 / 406 |
adipose | 100% | 4346.47 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 22.99 | 29 / 29 |
spleen | 100% | 6537.82 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 21.77 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 10.11 | 1 / 1 |
blood vessel | 100% | 4429.77 | 1334 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 2172.85 | 800 / 803 | 0% | 0 | 0 / 0 |
heart | 97% | 2602.39 | 832 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 96% | 25.16 | 77 / 80 |
peripheral blood | 94% | 4616.37 | 870 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006508 | Biological process | proteolysis |
GO_0016579 | Biological process | protein deubiquitination |
GO_0005929 | Cellular component | cilium |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005739 | Cellular component | mitochondrion |
GO_0005634 | Cellular component | nucleus |
GO_0101005 | Molecular function | deubiquitinase activity |
GO_0004197 | Molecular function | cysteine-type endopeptidase activity |
GO_0005515 | Molecular function | protein binding |
GO_0004843 | Molecular function | cysteine-type deubiquitinase activity |
Gene name | USP48 |
Protein name | Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) Ubiquitin specific peptidase 48 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Ubiquitin thioesterase 48) (Ubiquitin-specific peptidase 48) (Ubiquitin-specific protease 48) (Ubiquitin-specific-processing protease 48) |
Synonyms | USP31 |
Description | FUNCTION: Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins . May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites. . |
Accessions | ENST00000527823.5 H3BLX5 ENST00000421625.6 [Q86UV5-7] E9PRY5 ENST00000534705.5 ENST00000529637.5 [Q86UV5-8] ENST00000374732.7 B7ZKR8 Q86UV5 B7ZKS3 ENST00000308271.14 [Q86UV5-1] E9PJH5 A0A0A0MRS6 ENST00000526044.5 ENST00000374730.2 E9PJ87 ENST00000532737.1 E9PJ93 ENST00000400301.5 [Q86UV5-2] |