USP48 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006508Biological processproteolysis
GO_0016579Biological processprotein deubiquitination
GO_0005929Cellular componentcilium
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005739Cellular componentmitochondrion
GO_0005634Cellular componentnucleus
GO_0101005Molecular functiondeubiquitinase activity
GO_0004197Molecular functioncysteine-type endopeptidase activity
GO_0005515Molecular functionprotein binding
GO_0004843Molecular functioncysteine-type deubiquitinase activity

IV. Literature review

[source]
Gene nameUSP48
Protein nameUbiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12)
Ubiquitin specific peptidase 48
ubiquitinyl hydrolase 1 (EC 3.4.19.12)
Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Ubiquitin thioesterase 48) (Ubiquitin-specific peptidase 48) (Ubiquitin-specific protease 48) (Ubiquitin-specific-processing protease 48)
SynonymsUSP31
DescriptionFUNCTION: Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins . May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites. .

AccessionsENST00000527823.5
H3BLX5
ENST00000421625.6 [Q86UV5-7]
E9PRY5
ENST00000534705.5
ENST00000529637.5 [Q86UV5-8]
ENST00000374732.7
B7ZKR8
Q86UV5
B7ZKS3
ENST00000308271.14 [Q86UV5-1]
E9PJH5
A0A0A0MRS6
ENST00000526044.5
ENST00000374730.2
E9PJ87
ENST00000532737.1
E9PJ93
ENST00000400301.5 [Q86UV5-2]