UBE2G1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	18 studies	25% ± 10%	Explore
B cell	14 studies	21% ± 6%	Explore
plasma cell	14 studies	33% ± 13%	Explore
oligodendrocyte	12 studies	27% ± 8%	Explore
natural killer cell	11 studies	19% ± 3%	Explore
plasmablast	10 studies	39% ± 22%	Explore
microglial cell	8 studies	23% ± 7%	Explore
macrophage	8 studies	24% ± 7%	Explore
astrocyte	8 studies	28% ± 11%	Explore
T cell	8 studies	17% ± 2%	Explore
CD16-positive, CD56-dim natural killer cell, human	7 studies	18% ± 2%	Explore
glutamatergic neuron	7 studies	40% ± 23%	Explore
oligodendrocyte precursor cell	7 studies	24% ± 8%	Explore
CD8-positive, alpha-beta T cell	7 studies	19% ± 3%	Explore
epithelial cell	7 studies	38% ± 20%	Explore
ciliated cell	7 studies	25% ± 8%	Explore
memory B cell	7 studies	17% ± 2%	Explore
interneuron	6 studies	31% ± 20%	Explore
GABAergic neuron	6 studies	38% ± 19%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	20% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	19% ± 2%	Explore
CD4-positive, alpha-beta T cell	5 studies	18% ± 3%	Explore
neuron	5 studies	35% ± 14%	Explore
adipocyte	5 studies	22% ± 2%	Explore
cardiac muscle cell	5 studies	31% ± 7%	Explore
endothelial cell of lymphatic vessel	5 studies	23% ± 8%	Explore
type I pneumocyte	5 studies	21% ± 5%	Explore
pericyte	5 studies	21% ± 5%	Explore
gamma-delta T cell	5 studies	23% ± 12%	Explore
squamous epithelial cell	4 studies	42% ± 17%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	18% ± 2%	Explore
exhausted T cell	4 studies	19% ± 5%	Explore
precursor B cell	4 studies	22% ± 5%	Explore
myeloid cell	4 studies	20% ± 2%	Explore
lymphocyte	4 studies	26% ± 7%	Explore
hepatocyte	4 studies	34% ± 17%	Explore
fibroblast	4 studies	23% ± 4%	Explore
type II pneumocyte	4 studies	20% ± 5%	Explore
dendritic cell	4 studies	27% ± 11%	Explore
abnormal cell	4 studies	23% ± 9%	Explore
monocyte	4 studies	20% ± 3%	Explore
club cell	4 studies	21% ± 6%	Explore
smooth muscle cell	4 studies	21% ± 3%	Explore
basal cell	4 studies	42% ± 21%	Explore
goblet cell	4 studies	30% ± 18%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	18% ± 3%	Explore
classical monocyte	3 studies	21% ± 3%	Explore
non-classical monocyte	3 studies	22% ± 5%	Explore
granule cell	3 studies	19% ± 2%	Explore
retinal ganglion cell	3 studies	37% ± 19%	Explore
mucosal invariant T cell	3 studies	17% ± 1%	Explore
T follicular helper cell	3 studies	18% ± 2%	Explore
germinal center B cell	3 studies	29% ± 3%	Explore
muscle cell	3 studies	34% ± 13%	Explore
leukocyte	3 studies	22% ± 3%	Explore
alveolar macrophage	3 studies	21% ± 5%	Explore
transit amplifying cell	3 studies	37% ± 29%	Explore
keratinocyte	3 studies	31% ± 9%	Explore
plasmacytoid dendritic cell	3 studies	21% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	11 studies	31% ± 16%	Explore
lung	5 studies	21% ± 4%	Explore
heart	4 studies	20% ± 4%	Explore
liver	4 studies	27% ± 11%	Explore
peripheral blood	3 studies	21% ± 0%	Explore
intestine	3 studies	19% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	4249.68	1445 / 1445	100%	57.42	183 / 183
ovary	100%	1879.23	180 / 180	100%	33.52	430 / 430
stomach	100%	2443.83	359 / 359	100%	36.98	286 / 286
prostate	100%	2463.71	245 / 245	100%	51.32	501 / 502
breast	100%	2618.37	459 / 459	100%	45.36	1114 / 1118
intestine	100%	4166.41	966 / 966	100%	33.64	525 / 527
uterus	100%	2671.34	170 / 170	100%	40.74	457 / 459
lung	99%	2239.03	575 / 578	100%	41.12	1153 / 1155
brain	99%	2009.35	2619 / 2642	100%	40.72	705 / 705
skin	100%	3873.01	1808 / 1809	99%	35.48	468 / 472
bladder	100%	3178.14	21 / 21	99%	34.56	498 / 504
thymus	100%	1925.94	652 / 653	99%	28.76	598 / 605
kidney	100%	2305.98	89 / 89	97%	28.79	875 / 901
pancreas	98%	1349.25	320 / 328	99%	27.04	177 / 178
liver	100%	1815.62	226 / 226	96%	20.25	390 / 406
adrenal gland	100%	2450.05	258 / 258	85%	13.68	196 / 230
adipose	100%	2579.52	1204 / 1204	0%	0	0 / 0
blood vessel	100%	3154.36	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	66.88	29 / 29
muscle	100%	11178.67	803 / 803	0%	0	0 / 0
spleen	100%	2809.66	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	51.53	45 / 45
ureter	0%	0	0 / 0	100%	11.97	1 / 1
heart	96%	2540.82	825 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	95%	20.92	76 / 80
peripheral blood	92%	2721.58	856 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0070534	Biological process	protein K63-linked ubiquitination
GO_0006511	Biological process	ubiquitin-dependent protein catabolic process
GO_0070936	Biological process	protein K48-linked ubiquitination
GO_0000209	Biological process	protein polyubiquitination
GO_0043161	Biological process	proteasome-mediated ubiquitin-dependent protein catabolic process
GO_0070062	Cellular component	extracellular exosome
GO_0005829	Cellular component	cytosol
GO_0004842	Molecular function	ubiquitin-protein transferase activity
GO_0061631	Molecular function	ubiquitin conjugating enzyme activity
GO_0031625	Molecular function	ubiquitin protein ligase binding
GO_0005515	Molecular function	protein binding
GO_0005524	Molecular function	ATP binding

IV. Literature review

[source]

Gene name	UBE2G1
Protein name	E2 ubiquitin-conjugating enzyme (EC 2.3.2.23) Ubiquitin conjugating enzyme E2 G1 Ubiquitin-conjugating enzyme E2 G1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G1) (E217K) (UBC7) (Ubiquitin carrier protein G1) (Ubiquitin-protein ligase G1) [Cleaved into: Ubiquitin-conjugating enzyme E2 G1, N-terminally processed]
Synonyms	UBE2G hCG_33206
Description	FUNCTION: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4. .
Accessions	K7EPR7 ENST00000571953.5 I3L0Q0 I3L2Q4 P62253 ENST00000396981.7 ENST00000571980.1 ENST00000572484.5 I3L2H7 ENST00000574633.5

UBE2G1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review