UBE2E1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0016567Biological processprotein ubiquitination
GO_0006511Biological processubiquitin-dependent protein catabolic process
GO_0032020Biological processISG15-protein conjugation
GO_0070936Biological processprotein K48-linked ubiquitination
GO_0000209Biological processprotein polyubiquitination
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0000151Cellular componentubiquitin ligase complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0004842Molecular functionubiquitin-protein transferase activity
GO_0061631Molecular functionubiquitin conjugating enzyme activity
GO_0005524Molecular functionATP binding
GO_0042296Molecular functionISG15 transferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameUBE2E1
Protein nameUbiquitin-conjugating enzyme E2 E1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme E1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme E1) (UbcH6) (Ubiquitin carrier protein E1) (Ubiquitin-protein ligase E1)
E2 ubiquitin-conjugating enzyme (EC 2.3.2.23)
SynonymsUBCH6
DescriptionFUNCTION: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes the covalent attachment of ISG15 to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. In vitro also catalyzes 'Lys-48'-linked polyubiquitination. .

AccessionsENST00000424381.5 [P51965-2]
C9J2P0
ENST00000346855.7 [P51965-3]
B7Z306
H7C061
P51965
ENST00000306627.8 [P51965-1]
ENST00000467766.5
ENST00000452012.1
ENST00000442670.5