Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 29 studies | 31% ± 13% | |
pericyte | 23 studies | 26% ± 10% | |
macrophage | 22 studies | 29% ± 14% | |
fibroblast | 21 studies | 26% ± 9% | |
B cell | 15 studies | 23% ± 8% | |
smooth muscle cell | 15 studies | 22% ± 6% | |
astrocyte | 14 studies | 33% ± 13% | |
endothelial cell of lymphatic vessel | 12 studies | 32% ± 11% | |
microglial cell | 11 studies | 43% ± 13% | |
oligodendrocyte precursor cell | 11 studies | 32% ± 12% | |
epithelial cell | 10 studies | 36% ± 19% | |
oligodendrocyte | 10 studies | 28% ± 8% | |
ciliated cell | 9 studies | 27% ± 11% | |
classical monocyte | 8 studies | 23% ± 8% | |
GABAergic neuron | 8 studies | 33% ± 16% | |
connective tissue cell | 8 studies | 22% ± 6% | |
vein endothelial cell | 8 studies | 26% ± 13% | |
type I pneumocyte | 8 studies | 30% ± 9% | |
adipocyte | 8 studies | 25% ± 7% | |
myeloid cell | 7 studies | 32% ± 8% | |
type II pneumocyte | 7 studies | 31% ± 9% | |
monocyte | 7 studies | 29% ± 7% | |
dendritic cell | 7 studies | 31% ± 15% | |
non-classical monocyte | 6 studies | 25% ± 7% | |
conventional dendritic cell | 6 studies | 30% ± 12% | |
myofibroblast cell | 6 studies | 27% ± 8% | |
interneuron | 6 studies | 36% ± 17% | |
neuron | 6 studies | 37% ± 16% | |
plasma cell | 6 studies | 22% ± 8% | |
capillary endothelial cell | 6 studies | 26% ± 8% | |
Mueller cell | 6 studies | 21% ± 4% | |
endothelial cell of vascular tree | 6 studies | 24% ± 12% | |
basal cell | 6 studies | 40% ± 21% | |
club cell | 6 studies | 26% ± 10% | |
naive B cell | 6 studies | 20% ± 5% | |
plasmacytoid dendritic cell | 6 studies | 22% ± 7% | |
memory B cell | 5 studies | 17% ± 1% | |
precursor B cell | 5 studies | 31% ± 11% | |
mononuclear phagocyte | 5 studies | 28% ± 9% | |
hematopoietic precursor cell | 4 studies | 39% ± 12% | |
progenitor cell | 4 studies | 25% ± 4% | |
T cell | 4 studies | 24% ± 5% | |
endothelial cell of artery | 4 studies | 20% ± 3% | |
granule cell | 4 studies | 18% ± 3% | |
retinal ganglion cell | 4 studies | 41% ± 23% | |
pro-B cell | 4 studies | 29% ± 5% | |
retina horizontal cell | 4 studies | 23% ± 8% | |
retinal pigment epithelial cell | 4 studies | 29% ± 15% | |
cardiac muscle cell | 4 studies | 22% ± 4% | |
mesothelial cell | 4 studies | 31% ± 12% | |
lymphocyte | 4 studies | 25% ± 9% | |
glutamatergic neuron | 4 studies | 52% ± 11% | |
hematopoietic stem cell | 4 studies | 26% ± 12% | |
natural killer cell | 4 studies | 18% ± 3% | |
goblet cell | 4 studies | 35% ± 21% | |
kidney distal convoluted tubule epithelial cell | 3 studies | 19% ± 3% | |
immature B cell | 3 studies | 21% ± 4% | |
amacrine cell | 3 studies | 29% ± 9% | |
retinal bipolar neuron | 3 studies | 30% ± 6% | |
GABAergic amacrine cell | 3 studies | 18% ± 2% | |
glycinergic amacrine cell | 3 studies | 19% ± 2% | |
rod bipolar cell | 3 studies | 30% ± 9% | |
germinal center B cell | 3 studies | 23% ± 0% | |
hepatocyte | 3 studies | 32% ± 21% | |
muscle cell | 3 studies | 38% ± 22% | |
neural progenitor cell | 3 studies | 29% ± 7% | |
ependymal cell | 3 studies | 30% ± 12% | |
mast cell | 3 studies | 32% ± 6% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 41% ± 17% | |
intestinal crypt stem cell | 3 studies | 19% ± 2% | |
leukocyte | 3 studies | 31% ± 10% | |
alveolar macrophage | 3 studies | 31% ± 8% | |
chondrocyte | 3 studies | 27% ± 3% | |
respiratory goblet cell | 3 studies | 34% ± 15% | |
transit amplifying cell | 3 studies | 36% ± 27% | |
mucus secreting cell | 3 studies | 25% ± 6% | |
enteroendocrine cell | 3 studies | 26% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 3065.03 | 180 / 180 | 100% | 34.09 | 429 / 430 |
brain | 100% | 3311.43 | 2641 / 2642 | 100% | 43.71 | 702 / 705 |
lung | 100% | 3661.03 | 578 / 578 | 99% | 19.97 | 1149 / 1155 |
intestine | 100% | 3388.27 | 966 / 966 | 99% | 20.16 | 523 / 527 |
stomach | 100% | 2411.07 | 359 / 359 | 99% | 18.96 | 283 / 286 |
esophagus | 100% | 3798.26 | 1445 / 1445 | 99% | 12.33 | 181 / 183 |
breast | 100% | 3298.12 | 459 / 459 | 98% | 23.65 | 1095 / 1118 |
skin | 100% | 3674.81 | 1809 / 1809 | 98% | 24.10 | 462 / 472 |
bladder | 100% | 3587.33 | 21 / 21 | 97% | 20.68 | 487 / 504 |
prostate | 100% | 3367.78 | 245 / 245 | 97% | 21.92 | 485 / 502 |
pancreas | 98% | 1263.27 | 322 / 328 | 97% | 15.27 | 173 / 178 |
thymus | 100% | 3005.18 | 653 / 653 | 95% | 17.57 | 574 / 605 |
uterus | 100% | 3225.58 | 170 / 170 | 93% | 17.70 | 426 / 459 |
kidney | 100% | 2667.99 | 89 / 89 | 92% | 13.64 | 827 / 901 |
adrenal gland | 100% | 2268.93 | 258 / 258 | 84% | 9.71 | 193 / 230 |
liver | 100% | 1207.92 | 225 / 226 | 77% | 7.36 | 311 / 406 |
adipose | 100% | 3355.62 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3060.49 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 2835.67 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 3031.45 | 241 / 241 | 0% | 0 | 0 / 0 |
heart | 99% | 1951.59 | 850 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 15.75 | 43 / 45 |
eye | 0% | 0 | 0 / 0 | 93% | 12.37 | 74 / 80 |
lymph node | 0% | 0 | 0 / 0 | 90% | 19.78 | 26 / 29 |
peripheral blood | 82% | 2722.20 | 758 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0016567 | Biological process | protein ubiquitination |
GO_0006511 | Biological process | ubiquitin-dependent protein catabolic process |
GO_0032020 | Biological process | ISG15-protein conjugation |
GO_0070936 | Biological process | protein K48-linked ubiquitination |
GO_0000209 | Biological process | protein polyubiquitination |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0000151 | Cellular component | ubiquitin ligase complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005634 | Cellular component | nucleus |
GO_0004842 | Molecular function | ubiquitin-protein transferase activity |
GO_0061631 | Molecular function | ubiquitin conjugating enzyme activity |
GO_0005524 | Molecular function | ATP binding |
GO_0042296 | Molecular function | ISG15 transferase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | UBE2E1 |
Protein name | Ubiquitin-conjugating enzyme E2 E1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme E1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme E1) (UbcH6) (Ubiquitin carrier protein E1) (Ubiquitin-protein ligase E1) E2 ubiquitin-conjugating enzyme (EC 2.3.2.23) |
Synonyms | UBCH6 |
Description | FUNCTION: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes the covalent attachment of ISG15 to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. In vitro also catalyzes 'Lys-48'-linked polyubiquitination. . |
Accessions | ENST00000424381.5 [P51965-2] C9J2P0 ENST00000346855.7 [P51965-3] B7Z306 H7C061 P51965 ENST00000306627.8 [P51965-1] ENST00000467766.5 ENST00000452012.1 ENST00000442670.5 |