TRPS1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0001501Biological processskeletal system development
GO_0032330Biological processregulation of chondrocyte differentiation
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0032991Cellular componentprotein-containing complex
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0005515Molecular functionprotein binding
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0019904Molecular functionprotein domain specific binding
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameTRPS1
Protein nameTranscriptional repressor GATA binding 1
Zinc finger transcription factor Trps1 (Tricho-rhino-phalangeal syndrome type I protein) (Zinc finger protein GC79)
Synonyms
DescriptionFUNCTION: Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes. .

AccessionsENST00000519674.1
A0A1D5RMP4
ENST00000519076.5
H0YAV4
ENST00000422939.1
Q9UHF7
ENST00000451156.1
E7EVN4
F8W8T0
ENST00000640765.1 [Q9UHF7-1]
ENST00000520276.5 [Q9UHF7-3]
ENST00000518018.1
ENST00000517323.2
C9J6L7
ENST00000519815.5
E5RJ97
ENST00000395715.8 [Q9UHF7-2]
ENST00000395713.6
E5RFF3
H0YC29
ENST00000220888.9 [Q9UHF7-1]