TNS1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010761Biological processfibroblast migration
GO_0007044Biological processcell-substrate junction assembly
GO_0009986Cellular componentcell surface
GO_0005856Cellular componentcytoskeleton
GO_0005737Cellular componentcytoplasm
GO_0005925Cellular componentfocal adhesion
GO_0004721Molecular functionphosphoprotein phosphatase activity
GO_0005515Molecular functionprotein binding
GO_0003779Molecular functionactin binding
GO_0046872Molecular functionmetal ion binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameTNS1
Protein nameTensin 1
Tensin-1 (EC 3.1.3.-)
TNS1 protein
SynonymsTNS
hCG_1811886
DescriptionFUNCTION: May act as a protein phosphatase and/or a lipid phosphatase (Probable). Involved in fibrillar adhesion formation . Essential for myofibroblast differentiation and myofibroblast-mediated extracellular matrix deposition . Enhances RHOA activation in the presence of DLC1 . Plays a role in cell polarization and migration . May be involved in cartilage development and in linking signal transduction pathways to the cytoskeleton . .

AccessionsQ0VG55
C9JI43
Q6PJM3
ENST00000453356.1
C9JZT0
A0A994J515
ENST00000651849.1
H7C3Z4
A0A494C067
H0Y4U1
E9PGF5
A1L0S7
ENST00000449814.1
ENST00000413554.5
Q9HBL0
A0A3B3IRK7
C9JFT7
E7ERH1
B2RU35
ENST00000646520.1
ENST00000413280.5
ENST00000446688.5
ENST00000615025.6
E9PF55
ENST00000682258.1 [Q9HBL0-3]
ENST00000419504.6
C9J8K5
ENST00000705226.1
Q0VG54
ENST00000649572.1
E7EMG1
ENST00000446903.5
A0A2R8Y4T1
ENST00000171887.8 [Q9HBL0-1]
ENST00000423413.1
Q86VB0
ENST00000310858.10 [Q9HBL0-2]
ENST00000439083.5