TMUB1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0036503Biological processERAD pathway
GO_0005813Cellular componentcentrosome
GO_0005730Cellular componentnucleolus
GO_0055037Cellular componentrecycling endosome
GO_0045211Cellular componentpostsynaptic membrane
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTMUB1
Protein nameTransmembrane and ubiquitin like domain containing 1
Transmembrane and ubiquitin-like domain-containing protein 1 (Dendritic cell-derived ubiquitin-like protein) (DULP) (Hepatocyte odd protein shuttling protein) (Ubiquitin-like protein SB144) [Cleaved into: iHOPS]
Transmembrane and ubiquitin-like domain-containing protein 1
SynonymsDULP
HOPS
C7orf21
UNQ763/PRO1555
SB144
DescriptionFUNCTION: Involved in sterol-regulated ubiquitination and degradation of HMG-CoA reductase HMGCR . Involved in positive regulation of AMPA-selective glutamate receptor GRIA2 recycling to the cell surface (By similarity). Acts as a negative regulator of hepatocyte growth during regeneration (By similarity). .; FUNCTION: [iHOPS]: May contribute to the regulation of translation during cell-cycle progression. May contribute to the regulation of cell proliferation (By similarity). May be involved in centrosome assembly. Modulates stabilization and nucleolar localization of tumor suppressor CDKN2A and enhances association between CDKN2A and NPM1 (By similarity). .

AccessionsENST00000653405.1
C9JE12
ENST00000476627.5
ENST00000488752.5
ENST00000462940.1
Q9BVT8
C9JCW7
A0A590UJA9
ENST00000297533.9
ENST00000482202.5
ENST00000492838.1
ENST00000392818.7