TAF10 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006366Biological processtranscription by RNA polymerase II
GO_0001892Biological processembryonic placenta development
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0051123Biological processRNA polymerase II preinitiation complex assembly
GO_0006282Biological processregulation of DNA repair
GO_0060173Biological processlimb development
GO_0035264Biological processmulticellular organism growth
GO_0006338Biological processchromatin remodeling
GO_0060261Biological processpositive regulation of transcription initiation by RNA polymerase II
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0036285Biological processSAGA complex assembly
GO_0001756Biological processsomitogenesis
GO_0006355Biological processregulation of DNA-templated transcription
GO_0042789Biological processmRNA transcription by RNA polymerase II
GO_0006915Biological processapoptotic process
GO_0043484Biological processregulation of RNA splicing
GO_0006367Biological processtranscription initiation at RNA polymerase II promoter
GO_0048371Biological processlateral mesodermal cell differentiation
GO_0070365Biological processhepatocyte differentiation
GO_1905069Biological processallantois development
GO_0006352Biological processDNA-templated transcription initiation
GO_0000082Biological processG1/S transition of mitotic cell cycle
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005669Cellular componenttranscription factor TFIID complex
GO_0005654Cellular componentnucleoplasm
GO_0097550Cellular componenttranscription preinitiation complex
GO_0033276Cellular componenttranscription factor TFTC complex
GO_0005737Cellular componentcytoplasm
GO_0000124Cellular componentSAGA complex
GO_0001673Cellular componentmale germ cell nucleus
GO_0005634Cellular componentnucleus
GO_0070063Molecular functionRNA polymerase binding
GO_0003677Molecular functionDNA binding
GO_0019899Molecular functionenzyme binding
GO_1990841Molecular functionpromoter-specific chromatin binding
GO_0042802Molecular functionidentical protein binding
GO_0030331Molecular functionnuclear estrogen receptor binding
GO_0004402Molecular functionhistone acetyltransferase activity
GO_0016251Molecular functionRNA polymerase II general transcription initiation factor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTAF10
Protein nameTranscription initiation factor TFIID subunit 10 (STAF28) (Transcription initiation factor TFIID 30 kDa subunit) (TAF(II)30) (TAFII-30) (TAFII30)
TATA-box binding protein associated factor 10
SynonymsTAF2H
TAF2A
TAFII30
DescriptionFUNCTION: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription . TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) . The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 . TAF10 is also component of the PCAF histone acetylase complex, the TATA-binding protein-free TAF complex (TFTC) and the STAGA transcription coactivator-HAT complex . May regulate cyclin E expression (By similarity). .

AccessionsENST00000299424.9
ENST00000693612.1
ENST00000527248.3
A0A087WWP5
A0A8I5KQU8
Q12962