SDCCAG8 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030010Biological processestablishment of cell polarity
GO_0001764Biological processneuron migration
GO_0031023Biological processmicrotubule organizing center organization
GO_0030030Biological processcell projection organization
GO_0035148Biological processtube formation
GO_1902017Biological processregulation of cilium assembly
GO_0007098Biological processcentrosome cycle
GO_0005814Cellular componentcentriole
GO_0005911Cellular componentcell-cell junction
GO_0005813Cellular componentcentrosome
GO_0036064Cellular componentciliary basal body
GO_0005829Cellular componentcytosol
GO_0097733Cellular componentphotoreceptor cell cilium
GO_0034451Cellular componentcentriolar satellite
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSDCCAG8
Protein nameSHH signaling and ciliogenesis regulator SDCCAG8
Serologically defined colon cancer antigen 8
Serologically defined colon cancer antigen 8 (Antigen NY-CO-8) (Centrosomal colon cancer autoantigen protein) (hCCCAP)
SynonymsCCCAP
NPHP10
HSPC085
DescriptionFUNCTION: Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity). Also plays an essential role in ciliogenesis and subsequent Hedgehog signaling pathway that requires the presence of intact primary cilia for pathway activation. Mechanistically, interacts with and mediates RABEP2 centrosomal localization which is critical for ciliogenesis . .

AccessionsENST00000627744.2
ENST00000366541.8 [Q86SQ7-1]
ENST00000435549.1
S4R323
ENST00000476722.6
ENST00000630755.1
A0A0C4DG71
A0A0G2JQM2
ENST00000622598.3 [Q86SQ7-1]
ENST00000630785.2
A0A0G2JR50
A0A0G2JR20
Q86SQ7