SCFD1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	23 studies	29% ± 12%	Explore
fibroblast	20 studies	28% ± 11%	Explore
astrocyte	13 studies	32% ± 15%	Explore
macrophage	13 studies	29% ± 13%	Explore
pericyte	12 studies	25% ± 9%	Explore
microglial cell	12 studies	31% ± 12%	Explore
oligodendrocyte precursor cell	11 studies	36% ± 16%	Explore
oligodendrocyte	11 studies	28% ± 10%	Explore
GABAergic neuron	10 studies	42% ± 22%	Explore
glutamatergic neuron	10 studies	46% ± 25%	Explore
adipocyte	10 studies	33% ± 9%	Explore
epithelial cell	9 studies	37% ± 16%	Explore
ciliated cell	9 studies	24% ± 8%	Explore
plasma cell	8 studies	35% ± 15%	Explore
B cell	8 studies	24% ± 7%	Explore
smooth muscle cell	8 studies	23% ± 6%	Explore
myeloid cell	7 studies	28% ± 6%	Explore
dendritic cell	7 studies	34% ± 12%	Explore
mast cell	7 studies	24% ± 6%	Explore
type I pneumocyte	7 studies	27% ± 8%	Explore
natural killer cell	6 studies	21% ± 4%	Explore
non-classical monocyte	6 studies	25% ± 10%	Explore
neuron	6 studies	41% ± 15%	Explore
interneuron	6 studies	47% ± 24%	Explore
type II pneumocyte	6 studies	29% ± 8%	Explore
plasmacytoid dendritic cell	6 studies	23% ± 7%	Explore
retinal rod cell	5 studies	19% ± 3%	Explore
cardiac muscle cell	5 studies	22% ± 3%	Explore
T cell	5 studies	22% ± 5%	Explore
endothelial cell of lymphatic vessel	5 studies	28% ± 7%	Explore
monocyte	5 studies	33% ± 7%	Explore
goblet cell	5 studies	38% ± 25%	Explore
club cell	5 studies	28% ± 11%	Explore
basal cell	5 studies	33% ± 15%	Explore
classical monocyte	4 studies	24% ± 9%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	19% ± 3%	Explore
CD4-positive, alpha-beta T cell	4 studies	19% ± 3%	Explore
CD8-positive, alpha-beta T cell	4 studies	19% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	18% ± 2%	Explore
granule cell	4 studies	26% ± 6%	Explore
amacrine cell	4 studies	23% ± 3%	Explore
lymphocyte	4 studies	27% ± 8%	Explore
Mueller cell	4 studies	20% ± 4%	Explore
hepatocyte	4 studies	41% ± 18%	Explore
connective tissue cell	4 studies	27% ± 9%	Explore
respiratory goblet cell	4 studies	33% ± 11%	Explore
pancreatic A cell	3 studies	36% ± 12%	Explore
type B pancreatic cell	3 studies	41% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	20% ± 3%	Explore
conventional dendritic cell	3 studies	30% ± 13%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	18% ± 1%	Explore
plasmablast	3 studies	39% ± 16%	Explore
GABAergic interneuron	3 studies	30% ± 3%	Explore
glial cell	3 studies	25% ± 4%	Explore
retinal ganglion cell	3 studies	19% ± 1%	Explore
retina horizontal cell	3 studies	22% ± 3%	Explore
retinal bipolar neuron	3 studies	20% ± 1%	Explore
retinal cone cell	3 studies	21% ± 4%	Explore
mesothelial cell	3 studies	28% ± 8%	Explore
mononuclear phagocyte	3 studies	25% ± 4%	Explore
GABAergic amacrine cell	3 studies	24% ± 5%	Explore
glycinergic amacrine cell	3 studies	21% ± 0%	Explore
endothelial cell of vascular tree	3 studies	29% ± 16%	Explore
abnormal cell	3 studies	29% ± 13%	Explore
ependymal cell	3 studies	28% ± 12%	Explore
enteroendocrine cell	3 studies	27% ± 10%	Explore
leukocyte	3 studies	22% ± 4%	Explore
adventitial cell	3 studies	20% ± 4%	Explore
myofibroblast cell	3 studies	29% ± 13%	Explore
alveolar macrophage	3 studies	37% ± 10%	Explore
chondrocyte	3 studies	35% ± 8%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	16 studies	35% ± 20%	Explore
lung	9 studies	24% ± 7%	Explore
eye	7 studies	23% ± 12%	Explore
heart	4 studies	23% ± 2%	Explore
liver	4 studies	33% ± 15%	Explore
pancreas	3 studies	35% ± 11%	Explore
peripheral blood	3 studies	25% ± 3%	Explore
intestine	3 studies	22% ± 7%	Explore
adipose	3 studies	34% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	2589.00	459 / 459	100%	7.90	1118 / 1118
esophagus	100%	2276.37	1445 / 1445	100%	6.10	183 / 183
lung	100%	2454.02	578 / 578	100%	6.46	1155 / 1155
ovary	100%	2463.68	180 / 180	100%	4.44	430 / 430
pancreas	100%	2418.98	328 / 328	100%	5.66	178 / 178
prostate	100%	2503.76	245 / 245	100%	7.40	502 / 502
brain	100%	1914.18	2638 / 2642	100%	5.66	705 / 705
uterus	100%	2633.50	170 / 170	100%	6.00	458 / 459
thymus	100%	2963.02	653 / 653	100%	7.25	603 / 605
adrenal gland	100%	2730.40	258 / 258	100%	6.18	229 / 230
kidney	100%	2014.24	89 / 89	100%	4.67	897 / 901
liver	100%	1694.85	226 / 226	100%	3.72	404 / 406
bladder	100%	2226.38	21 / 21	99%	5.44	501 / 504
stomach	100%	1944.23	359 / 359	99%	5.02	283 / 286
intestine	100%	2284.77	966 / 966	99%	4.98	520 / 527
skin	100%	2677.92	1809 / 1809	97%	5.06	456 / 472
blood vessel	100%	2488.57	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	4.75	29 / 29
spleen	100%	2457.55	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	5.47	45 / 45
ureter	0%	0	0 / 0	100%	2.41	1 / 1
adipose	100%	2633.13	1203 / 1204	0%	0	0 / 0
muscle	100%	1841.96	801 / 803	0%	0	0 / 0
heart	99%	1610.90	850 / 861	0%	0	0 / 0
peripheral blood	90%	1583.92	833 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	86%	3.05	69 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006890	Biological process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO_0006892	Biological process	post-Golgi vesicle-mediated transport
GO_0006886	Biological process	intracellular protein transport
GO_0051223	Biological process	regulation of protein transport
GO_0060628	Biological process	regulation of ER to Golgi vesicle-mediated transport
GO_0001666	Biological process	response to hypoxia
GO_1902902	Biological process	negative regulation of autophagosome assembly
GO_0000902	Biological process	cell morphogenesis
GO_0006888	Biological process	endoplasmic reticulum to Golgi vesicle-mediated transport
GO_0009636	Biological process	response to toxic substance
GO_0005801	Cellular component	cis-Golgi network
GO_0005886	Cellular component	plasma membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0000139	Cellular component	Golgi membrane
GO_0005829	Cellular component	cytosol
GO_0005798	Cellular component	Golgi-associated vesicle
GO_0032580	Cellular component	Golgi cisterna membrane
GO_0044877	Molecular function	protein-containing complex binding
GO_0005515	Molecular function	protein binding
GO_0019905	Molecular function	syntaxin binding

IV. Literature review

[source]

Gene name	SCFD1
Protein name	Sec1 family domain containing 1 (cDNA FLJ58612, highly similar to Sec1 family domain-containing protein 1) Sec1 family domain containing 1 Sec1 family domain-containing protein 1 (SLY1 homolog) (Sly1p) (Syntaxin-binding protein 1-like 2)
Synonyms	KIAA0917 STXBP1L2 FKSG23 C14orf163
Description	FUNCTION: Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi (By similarity). .
Accessions	ENST00000678475.1 G3V5F3 G3V4I1 G3V5E2 A0A7I2V4B8 ENST00000676834.1 ENST00000396629.6 [Q8WVM8-2] ENST00000678716.1 ENST00000555259.5 B7Z5N7 H0YJS6 A0A7I2YQR2 ENST00000554437.6 ENST00000678124.1 [Q8WVM8-3] ENST00000677340.1 G3V3K9 ENST00000679342.1 ENST00000677690.1 A0A7I2V448 ENST00000311943.11 A0A7I2V3B4 ENST00000677974.1 A0A7I2V414 ENST00000679096.1 ENST00000544052.6 [Q8WVM8-3] A0A7I2V5Z4 ENST00000676812.1 ENST00000556768.5 A0A7I2V2U5 A0A7I2YQQ1 ENST00000676914.1 ENST00000678402.1 ENST00000554776.5 ENST00000679075.1 ENST00000676473.1 ENST00000557713.5 A0A7I2V362 H0YJY1 ENST00000677456.1 ENST00000676509.1 ENST00000678760.1 ENST00000679165.1 A0A7I2V534 A0A7I2V5R9 ENST00000678669.1 ENST00000463622.6 A0A7I2V4U2 ENST00000676876.1 A0A7I2YQG3 ENST00000677413.1 ENST00000676465.1 ENST00000676674.1 A0A7I2V4B9 A0A7I2V5L2 A0A7I2V321 ENST00000679102.1 ENST00000678399.1 ENST00000677637.1 ENST00000676954.1 A0A7I2V3Y3 ENST00000678396.1 A0A7I2V3G4 A0A7I2V4R0 J3KNG4 ENST00000678579.1 G3V2M8 G3V363 ENST00000458591.7 [Q8WVM8-1] G3V551 A0A7I2V590 A0A7I2V5H5 ENST00000676658.1 ENST00000469043.2 ENST00000484733.6 ENST00000557076.6 A0A7I2V320 A0A7I2V5I2 ENST00000553693.6 ENST00000677176.1 Q8WVM8 H0YIZ7 A0A7I2V3C9 A0A7I2V4J1 ENST00000676520.1

SCFD1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review