Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 29 studies | 53% ± 21% | |
astrocyte | 19 studies | 56% ± 19% | |
fibroblast | 18 studies | 49% ± 21% | |
macrophage | 16 studies | 51% ± 25% | |
microglial cell | 16 studies | 61% ± 18% | |
oligodendrocyte | 15 studies | 42% ± 15% | |
pericyte | 15 studies | 48% ± 24% | |
oligodendrocyte precursor cell | 14 studies | 56% ± 18% | |
glutamatergic neuron | 12 studies | 64% ± 22% | |
endothelial cell of lymphatic vessel | 11 studies | 53% ± 25% | |
smooth muscle cell | 11 studies | 47% ± 16% | |
GABAergic neuron | 11 studies | 67% ± 22% | |
adipocyte | 11 studies | 59% ± 21% | |
epithelial cell | 9 studies | 43% ± 19% | |
myeloid cell | 9 studies | 46% ± 19% | |
capillary endothelial cell | 8 studies | 32% ± 18% | |
mesothelial cell | 8 studies | 47% ± 18% | |
mast cell | 7 studies | 32% ± 10% | |
non-classical monocyte | 6 studies | 29% ± 12% | |
neuron | 6 studies | 60% ± 22% | |
interneuron | 6 studies | 77% ± 14% | |
dendritic cell | 6 studies | 42% ± 10% | |
ciliated cell | 6 studies | 24% ± 5% | |
basal cell | 6 studies | 45% ± 23% | |
retinal cone cell | 5 studies | 54% ± 23% | |
cardiac muscle cell | 5 studies | 63% ± 14% | |
vein endothelial cell | 5 studies | 50% ± 21% | |
monocyte | 5 studies | 69% ± 6% | |
myofibroblast cell | 5 studies | 40% ± 27% | |
type I pneumocyte | 5 studies | 29% ± 10% | |
cholangiocyte | 4 studies | 54% ± 23% | |
classical monocyte | 4 studies | 28% ± 5% | |
granule cell | 4 studies | 57% ± 13% | |
B cell | 4 studies | 25% ± 5% | |
endothelial cell of artery | 4 studies | 29% ± 12% | |
Mueller cell | 4 studies | 48% ± 17% | |
amacrine cell | 4 studies | 57% ± 10% | |
retina horizontal cell | 4 studies | 55% ± 14% | |
retinal ganglion cell | 4 studies | 67% ± 21% | |
retinal rod cell | 4 studies | 62% ± 13% | |
T cell | 4 studies | 25% ± 6% | |
connective tissue cell | 4 studies | 35% ± 18% | |
endothelial cell of sinusoid | 3 studies | 38% ± 13% | |
hepatic stellate cell | 3 studies | 58% ± 18% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 51% ± 8% | |
GABAergic interneuron | 3 studies | 76% ± 5% | |
glial cell | 3 studies | 37% ± 17% | |
progenitor cell | 3 studies | 50% ± 4% | |
endocardial cell | 3 studies | 34% ± 14% | |
mononuclear phagocyte | 3 studies | 44% ± 17% | |
GABAergic amacrine cell | 3 studies | 66% ± 10% | |
OFF-bipolar cell | 3 studies | 43% ± 15% | |
ON-bipolar cell | 3 studies | 43% ± 14% | |
glycinergic amacrine cell | 3 studies | 48% ± 9% | |
lymphocyte | 3 studies | 32% ± 11% | |
endothelial cell of vascular tree | 3 studies | 62% ± 18% | |
hepatocyte | 3 studies | 69% ± 20% | |
retinal pigment epithelial cell | 3 studies | 51% ± 27% | |
abnormal cell | 3 studies | 35% ± 22% | |
neural progenitor cell | 3 studies | 47% ± 19% | |
ependymal cell | 3 studies | 69% ± 13% | |
alveolar macrophage | 3 studies | 70% ± 9% | |
club cell | 3 studies | 33% ± 15% | |
natural killer cell | 3 studies | 26% ± 5% | |
respiratory goblet cell | 3 studies | 46% ± 15% | |
type II pneumocyte | 3 studies | 19% ± 3% | |
muscle cell | 3 studies | 47% ± 22% | |
leukocyte | 3 studies | 47% ± 16% | |
transit amplifying cell | 3 studies | 41% ± 35% | |
mucus secreting cell | 3 studies | 47% ± 14% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 17 studies | 57% ± 20% | |
lung | 6 studies | 33% ± 11% | |
heart | 5 studies | 49% ± 15% | |
eye | 5 studies | 63% ± 15% | |
peripheral blood | 3 studies | 21% ± 4% | |
intestine | 3 studies | 19% ± 3% | |
adipose | 3 studies | 60% ± 20% | |
kidney | 3 studies | 51% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2752.33 | 1445 / 1445 | 99% | 8.87 | 182 / 183 |
brain | 100% | 2022.82 | 2639 / 2642 | 99% | 11.97 | 701 / 705 |
prostate | 100% | 2485.92 | 245 / 245 | 97% | 8.96 | 485 / 502 |
intestine | 100% | 2733.15 | 966 / 966 | 96% | 5.76 | 507 / 527 |
stomach | 100% | 1940.79 | 359 / 359 | 96% | 6.55 | 274 / 286 |
kidney | 100% | 2063.15 | 89 / 89 | 95% | 8.09 | 860 / 901 |
thymus | 100% | 2707.76 | 652 / 653 | 95% | 8.74 | 573 / 605 |
ovary | 100% | 3493.96 | 180 / 180 | 92% | 4.13 | 395 / 430 |
skin | 100% | 3984.03 | 1809 / 1809 | 91% | 6.23 | 430 / 472 |
breast | 100% | 3371.24 | 459 / 459 | 90% | 7.01 | 1010 / 1118 |
lung | 100% | 2721.63 | 577 / 578 | 88% | 5.11 | 1020 / 1155 |
uterus | 100% | 3162.88 | 170 / 170 | 86% | 4.13 | 394 / 459 |
bladder | 100% | 3228.24 | 21 / 21 | 85% | 4.43 | 430 / 504 |
adrenal gland | 100% | 2071.71 | 258 / 258 | 83% | 4.29 | 190 / 230 |
pancreas | 73% | 529.14 | 238 / 328 | 93% | 5.10 | 165 / 178 |
liver | 99% | 913.21 | 223 / 226 | 64% | 2.80 | 260 / 406 |
adipose | 100% | 3955.77 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2970.71 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 1753.34 | 241 / 241 | 0% | 0 | 0 / 0 |
heart | 98% | 1564.61 | 840 / 861 | 0% | 0 | 0 / 0 |
muscle | 95% | 937.61 | 763 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 85% | 4.37 | 68 / 80 |
tonsil | 0% | 0 | 0 / 0 | 80% | 4.41 | 36 / 45 |
peripheral blood | 79% | 915.83 | 732 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 31% | 0.81 | 9 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006914 | Biological process | autophagy |
GO_0042552 | Biological process | myelination |
GO_0005774 | Cellular component | vacuolar membrane |
GO_0010008 | Cellular component | endosome membrane |
GO_0030424 | Cellular component | axon |
GO_0005829 | Cellular component | cytosol |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0016020 | Cellular component | membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0019902 | Molecular function | phosphatase binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0005515 | Molecular function | protein binding |
GO_0035091 | Molecular function | phosphatidylinositol binding |
GO_0019208 | Molecular function | phosphatase regulator activity |
Gene name | SBF2 |
Protein name | SET binding factor 2 Myotubularin-related protein 13 (Inactive phosphatidylinositol 3-phosphatase 13) (SET-binding factor 2) |
Synonyms | MTMR13 CMT4B2 KIAA1766 |
Description | FUNCTION: Guanine nucleotide exchange factor (GEF) which activates RAB21 and possibly RAB28 . Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form . In response to starvation-induced autophagy, activates RAB21 which in turn binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediated autophagosome-lysosome fusion . Acts as an adapter for the phosphatase MTMR2 (By similarity). Increases MTMR2 catalytic activity towards phosphatidylinositol 3,5-bisphosphate and to a lesser extent towards phosphatidylinositol 3-phosphate (By similarity). . |
Accessions | A0A8I5KQC6 ENST00000692068.1 A0A8I5KT92 A0A8I5KTA9 ENST00000690944.1 ENST00000689597.1 ENST00000533770.6 [Q86WG5-3] A0A6Q8PH13 ENST00000690003.1 ENST00000689342.1 ENST00000687256.1 ENST00000420722.3 ENST00000675281.2 ENST00000689128.1 ENST00000687300.1 A0A8I5KWU9 ENST00000256190.13 [Q86WG5-1] ENST00000688739.1 Q86WG5 A0A8I5KWJ6 A0A8I5KUI7 A0A6Q8PHP8 A0A8I5KT45 H0YD05 ENST00000688206.1 ENST00000693181.1 A0A8I5KNS4 A0A8I5KY55 A0A8I5KTX3 ENST00000676387.2 ENST00000688344.1 ENST00000689940.1 A0A8I5QJN8 A0A8I5KQ02 A0A8I5KUI9 ENST00000692716.1 ENST00000689674.1 A0A8I5KRQ5 A0A8I5KSD8 A0A6Q8PH87 ENST00000686079.1 ENST00000693212.1 A0A8I5QL20 ENST00000693022.1 A0A8I5KVJ0 ENST00000690234.1 A0A8I5QKS9 H0Y767 ENST00000689258.1 A0A8I5KXJ7 A0A8I5KWY5 A0A8I5KUN8 ENST00000525040.5 ENST00000687210.1 ENST00000530741.2 ENST00000693201.1 A0A8I5KRP8 ENST00000690806.1 ENST00000676324.2 |