SAR1A | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	28 studies	29% ± 10%	Explore
natural killer cell	26 studies	23% ± 7%	Explore
endothelial cell	22 studies	25% ± 10%	Explore
smooth muscle cell	17 studies	22% ± 7%	Explore
pericyte	16 studies	23% ± 7%	Explore
connective tissue cell	12 studies	31% ± 12%	Explore
basal cell	11 studies	27% ± 12%	Explore
T cell	10 studies	23% ± 5%	Explore
plasma cell	9 studies	27% ± 14%	Explore
classical monocyte	9 studies	23% ± 10%	Explore
CD8-positive, alpha-beta T cell	9 studies	21% ± 7%	Explore
macrophage	9 studies	21% ± 7%	Explore
gamma-delta T cell	9 studies	23% ± 10%	Explore
endothelial cell of vascular tree	9 studies	22% ± 6%	Explore
epithelial cell	9 studies	37% ± 19%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	23% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	24% ± 7%	Explore
adipocyte	8 studies	22% ± 11%	Explore
type II pneumocyte	7 studies	23% ± 13%	Explore
mature NK T cell	7 studies	22% ± 6%	Explore
myofibroblast cell	7 studies	25% ± 5%	Explore
endothelial cell of artery	7 studies	19% ± 2%	Explore
secretory cell	7 studies	24% ± 9%	Explore
endothelial cell of lymphatic vessel	7 studies	21% ± 6%	Explore
type I pneumocyte	6 studies	29% ± 9%	Explore
CD4-positive, alpha-beta T cell	6 studies	23% ± 5%	Explore
ciliated cell	6 studies	34% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	20% ± 3%	Explore
mast cell	5 studies	20% ± 3%	Explore
monocyte	5 studies	23% ± 5%	Explore
vein endothelial cell	5 studies	18% ± 3%	Explore
goblet cell	5 studies	31% ± 16%	Explore
plasmablast	4 studies	46% ± 21%	Explore
pancreatic A cell	4 studies	30% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	17% ± 1%	Explore
non-classical monocyte	4 studies	31% ± 11%	Explore
B cell	4 studies	25% ± 3%	Explore
abnormal cell	4 studies	22% ± 4%	Explore
myeloid cell	4 studies	31% ± 8%	Explore
club cell	4 studies	25% ± 14%	Explore
capillary endothelial cell	4 studies	18% ± 2%	Explore
GABAergic neuron	4 studies	33% ± 11%	Explore
glutamatergic neuron	4 studies	41% ± 13%	Explore
oligodendrocyte	4 studies	22% ± 1%	Explore
type B pancreatic cell	3 studies	38% ± 7%	Explore
leukocyte	3 studies	21% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	25% ± 6%	Explore
conventional dendritic cell	3 studies	30% ± 11%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	30% ± 8%	Explore
hematopoietic precursor cell	3 studies	23% ± 7%	Explore
glomerular endothelial cell	3 studies	18% ± 1%	Explore
placental villous trophoblast	3 studies	24% ± 6%	Explore
innate lymphoid cell	3 studies	23% ± 4%	Explore
astrocyte	3 studies	26% ± 5%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	24% ± 3%	Explore
pancreatic ductal cell	3 studies	38% ± 14%	Explore
oligodendrocyte precursor cell	3 studies	26% ± 2%	Explore
transit amplifying cell	3 studies	22% ± 7%	Explore
interneuron	3 studies	37% ± 16%	Explore
neuron	3 studies	30% ± 13%	Explore
mononuclear phagocyte	3 studies	27% ± 7%	Explore
plasmacytoid dendritic cell	3 studies	20% ± 6%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	9 studies	29% ± 10%	Explore
peripheral blood	6 studies	26% ± 7%	Explore
brain	6 studies	29% ± 9%	Explore
placenta	4 studies	20% ± 4%	Explore
eye	4 studies	24% ± 3%	Explore
uterus	4 studies	25% ± 9%	Explore
pancreas	3 studies	36% ± 7%	Explore
kidney	3 studies	17% ± 1%	Explore
breast	3 studies	19% ± 1%	Explore
intestine	3 studies	28% ± 14%	Explore
liver	3 studies	32% ± 16%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	6074.38	21 / 21	100%	50.01	504 / 504
breast	100%	7598.46	459 / 459	100%	78.04	1118 / 1118
esophagus	100%	5815.73	1445 / 1445	100%	34.18	183 / 183
kidney	100%	4697.02	89 / 89	100%	47.84	901 / 901
liver	100%	3868.81	226 / 226	100%	37.57	406 / 406
lung	100%	8047.73	578 / 578	100%	53.05	1155 / 1155
ovary	100%	5990.54	180 / 180	100%	37.00	430 / 430
pancreas	100%	2890.10	328 / 328	100%	51.63	178 / 178
prostate	100%	5696.36	245 / 245	100%	61.56	502 / 502
stomach	100%	4622.76	359 / 359	100%	37.52	286 / 286
uterus	100%	6024.65	170 / 170	100%	57.80	459 / 459
brain	100%	4517.85	2639 / 2642	100%	55.63	705 / 705
thymus	100%	6006.19	653 / 653	100%	57.25	604 / 605
intestine	100%	5613.70	966 / 966	100%	42.37	525 / 527
skin	100%	7696.64	1809 / 1809	99%	48.21	468 / 472
adrenal gland	100%	7501.99	258 / 258	99%	55.52	228 / 230
adipose	100%	9070.43	1204 / 1204	0%	0	0 / 0
blood vessel	100%	6396.81	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	45.03	29 / 29
muscle	100%	4560.29	803 / 803	0%	0	0 / 0
spleen	100%	6159.48	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	48.35	45 / 45
ureter	0%	0	0 / 0	100%	40.49	1 / 1
heart	99%	4478.62	855 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	96%	39.22	77 / 80
peripheral blood	96%	3332.42	894 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_1990253	Biological process	cellular response to leucine starvation
GO_1903432	Biological process	regulation of TORC1 signaling
GO_0003400	Biological process	regulation of COPII vesicle coating
GO_0006886	Biological process	intracellular protein transport
GO_0061024	Biological process	membrane organization
GO_0070863	Biological process	positive regulation of protein exit from endoplasmic reticulum
GO_0016050	Biological process	vesicle organization
GO_0042953	Biological process	lipoprotein transport
GO_0006888	Biological process	endoplasmic reticulum to Golgi vesicle-mediated transport
GO_1904262	Biological process	negative regulation of TORC1 signaling
GO_0048208	Biological process	COPII vesicle coating
GO_0090110	Biological process	COPII-coated vesicle cargo loading
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0030127	Cellular component	COPII vesicle coat
GO_0070971	Cellular component	endoplasmic reticulum exit site
GO_0005829	Cellular component	cytosol
GO_0032580	Cellular component	Golgi cisterna membrane
GO_0005765	Cellular component	lysosomal membrane
GO_0003924	Molecular function	GTPase activity
GO_0003925	Molecular function	G protein activity
GO_0005525	Molecular function	GTP binding
GO_0140785	Molecular function	amino acid sensor activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	SAR1A
Protein name	GTP-binding protein SAR1a Secretion associated Ras related GTPase 1A GTP-binding protein SAR1a (COPII-associated small GTPase)
Synonyms	SARA1 SAR1 SARA hCG_1787550
Description	FUNCTION: Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES). .
Accessions	ENST00000373238.5 [Q9NR31-1] Q9NR31 X1WI22 ENST00000373242.6 [Q9NR31-1] Q5SQT9 ENST00000452767.1 ENST00000373241.9 [Q9NR31-1] ENST00000373239.2 ENST00000373236.1 H0Y5E8 Q5SQT8

SAR1A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review