Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 23 studies | 28% ± 11% | |
macrophage | 15 studies | 27% ± 10% | |
fibroblast | 13 studies | 24% ± 8% | |
mast cell | 12 studies | 23% ± 9% | |
endothelial cell of lymphatic vessel | 12 studies | 21% ± 5% | |
oligodendrocyte | 12 studies | 29% ± 11% | |
glutamatergic neuron | 11 studies | 41% ± 25% | |
astrocyte | 11 studies | 38% ± 17% | |
oligodendrocyte precursor cell | 10 studies | 27% ± 12% | |
CD8-positive, alpha-beta T cell | 10 studies | 22% ± 7% | |
pericyte | 9 studies | 20% ± 6% | |
microglial cell | 9 studies | 25% ± 10% | |
adipocyte | 9 studies | 27% ± 7% | |
natural killer cell | 8 studies | 21% ± 7% | |
ciliated cell | 8 studies | 29% ± 12% | |
myeloid cell | 8 studies | 27% ± 8% | |
smooth muscle cell | 8 studies | 19% ± 2% | |
regulatory T cell | 8 studies | 21% ± 8% | |
classical monocyte | 7 studies | 22% ± 7% | |
non-classical monocyte | 7 studies | 21% ± 6% | |
neuron | 7 studies | 35% ± 16% | |
interneuron | 7 studies | 38% ± 25% | |
myofibroblast cell | 7 studies | 18% ± 3% | |
epithelial cell | 7 studies | 40% ± 17% | |
GABAergic neuron | 7 studies | 45% ± 20% | |
lymphocyte | 6 studies | 20% ± 6% | |
monocyte | 6 studies | 22% ± 2% | |
plasmablast | 5 studies | 35% ± 17% | |
retinal ganglion cell | 5 studies | 57% ± 19% | |
basal cell | 5 studies | 34% ± 18% | |
retina horizontal cell | 5 studies | 32% ± 12% | |
dendritic cell | 5 studies | 30% ± 12% | |
CD4-positive, alpha-beta T cell | 5 studies | 27% ± 9% | |
secretory cell | 4 studies | 29% ± 17% | |
hematopoietic precursor cell | 4 studies | 27% ± 6% | |
cardiac muscle cell | 4 studies | 21% ± 1% | |
erythroblast | 4 studies | 28% ± 14% | |
type I pneumocyte | 4 studies | 23% ± 3% | |
plasmacytoid dendritic cell | 4 studies | 19% ± 5% | |
ionocyte | 3 studies | 24% ± 2% | |
pancreatic A cell | 3 studies | 36% ± 16% | |
type B pancreatic cell | 3 studies | 47% ± 20% | |
leukocyte | 3 studies | 23% ± 5% | |
CD16-negative, CD56-bright natural killer cell, human | 3 studies | 19% ± 3% | |
conventional dendritic cell | 3 studies | 35% ± 8% | |
connective tissue cell | 3 studies | 21% ± 6% | |
GABAergic interneuron | 3 studies | 25% ± 2% | |
glial cell | 3 studies | 21% ± 7% | |
placental villous trophoblast | 3 studies | 34% ± 8% | |
plasma cell | 3 studies | 36% ± 14% | |
club cell | 3 studies | 21% ± 4% | |
capillary endothelial cell | 3 studies | 17% ± 2% | |
amacrine cell | 3 studies | 25% ± 7% | |
retinal cone cell | 3 studies | 26% ± 8% | |
retinal pigment epithelial cell | 3 studies | 30% ± 10% | |
retinal rod cell | 3 studies | 18% ± 2% | |
vein endothelial cell | 3 studies | 22% ± 7% | |
OFF-bipolar cell | 3 studies | 24% ± 7% | |
ON-bipolar cell | 3 studies | 27% ± 11% | |
respiratory goblet cell | 3 studies | 26% ± 9% | |
hepatocyte | 3 studies | 44% ± 22% | |
muscle cell | 3 studies | 32% ± 10% | |
type II pneumocyte | 3 studies | 20% ± 5% | |
abnormal cell | 3 studies | 36% ± 12% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 34% ± 13% | |
enteroendocrine cell | 3 studies | 23% ± 7% | |
goblet cell | 3 studies | 30% ± 15% | |
alveolar macrophage | 3 studies | 27% ± 8% | |
erythrocyte | 3 studies | 32% ± 16% | |
transit amplifying cell | 3 studies | 36% ± 21% | |
granule cell | 3 studies | 25% ± 6% | |
effector CD8-positive, alpha-beta T cell | 3 studies | 27% ± 4% | |
CD4-positive, alpha-beta memory T cell | 3 studies | 18% ± 2% | |
T cell | 3 studies | 18% ± 3% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 17 studies | 32% ± 20% | |
lung | 7 studies | 26% ± 13% | |
peripheral blood | 6 studies | 20% ± 4% | |
eye | 5 studies | 25% ± 8% | |
liver | 4 studies | 37% ± 14% | |
pancreas | 3 studies | 39% ± 16% | |
placenta | 3 studies | 21% ± 3% | |
heart | 3 studies | 19% ± 3% | |
intestine | 3 studies | 21% ± 4% | |
adipose | 3 studies | 22% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 4830.63 | 459 / 459 | 100% | 31.64 | 1118 / 1118 |
esophagus | 100% | 5630.91 | 1445 / 1445 | 100% | 37.46 | 183 / 183 |
intestine | 100% | 5271.70 | 966 / 966 | 100% | 28.93 | 527 / 527 |
ovary | 100% | 3139.01 | 180 / 180 | 100% | 18.30 | 430 / 430 |
lung | 100% | 4793.62 | 577 / 578 | 100% | 27.73 | 1155 / 1155 |
bladder | 100% | 5386.43 | 21 / 21 | 100% | 23.18 | 503 / 504 |
brain | 100% | 4960.75 | 2636 / 2642 | 100% | 24.83 | 705 / 705 |
stomach | 100% | 3855.39 | 358 / 359 | 100% | 29.46 | 286 / 286 |
uterus | 100% | 5065.71 | 170 / 170 | 100% | 24.94 | 457 / 459 |
liver | 100% | 3316.27 | 225 / 226 | 100% | 17.51 | 406 / 406 |
prostate | 100% | 3955.31 | 244 / 245 | 100% | 20.28 | 501 / 502 |
thymus | 100% | 4046.68 | 652 / 653 | 100% | 19.22 | 602 / 605 |
skin | 100% | 6783.02 | 1808 / 1809 | 99% | 28.99 | 468 / 472 |
kidney | 100% | 3740.24 | 89 / 89 | 98% | 15.68 | 887 / 901 |
adrenal gland | 100% | 6301.22 | 258 / 258 | 96% | 21.79 | 221 / 230 |
pancreas | 89% | 1624.70 | 291 / 328 | 99% | 23.27 | 177 / 178 |
adipose | 100% | 5314.24 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 5517.53 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 24.54 | 29 / 29 |
muscle | 100% | 12732.72 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 4324.83 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 28.48 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 10.67 | 1 / 1 |
heart | 97% | 5333.90 | 831 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 96% | 14.87 | 77 / 80 |
peripheral blood | 87% | 3305.78 | 809 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0042176 | Biological process | regulation of protein catabolic process |
GO_0043161 | Biological process | proteasome-mediated ubiquitin-dependent protein catabolic process |
GO_0035578 | Cellular component | azurophil granule lumen |
GO_0000502 | Cellular component | proteasome complex |
GO_0034515 | Cellular component | proteasome storage granule |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0008540 | Cellular component | proteasome regulatory particle, base subcomplex |
GO_0005576 | Cellular component | extracellular region |
GO_0005838 | Cellular component | proteasome regulatory particle |
GO_0022624 | Cellular component | proteasome accessory complex |
GO_0016020 | Cellular component | membrane |
GO_0005634 | Cellular component | nucleus |
GO_0030234 | Molecular function | enzyme regulator activity |
GO_0005515 | Molecular function | protein binding |
GO_0031625 | Molecular function | ubiquitin protein ligase binding |
Gene name | PSMD1 |
Protein name | 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112) Proteasome 26S subunit, non-ATPase 1 |
Synonyms | |
Description | FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. . FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. . FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. . FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. . FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. . FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. . FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. . FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. . FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. . FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. . FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. . FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. . FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. . FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. . FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. . |
Accessions | ENST00000676818.1 ENST00000431051.6 ENST00000678112.1 Q05CW6 ENST00000677180.1 F8WCE3 A0A7I2V4A5 ENST00000678241.1 ENST00000676740.1 ENST00000444007.2 A0A7I2YQI9 ENST00000677000.1 Q05BX4 ENST00000373635.9 [Q99460-2] ENST00000677259.1 ENST00000679095.1 A0A7I2V262 ENST00000679034.1 H7BZR6 C9J9M4 A0A7P0MW50 A0A7I2V479 A0A087WW66 ENST00000677724.1 ENST00000677158.1 ENST00000619128.5 A0A7I2YQY1 ENST00000409643.6 ENST00000677230.1 [Q99460-1] A0A7I2V491 A0A7I2V2K8 ENST00000678679.1 A0A7I2V4X0 ENST00000308696.11 [Q99460-1] A0A7I2V641 Q99460 A0A7I2V523 ENST00000440838.5 ENST00000678460.1 ENST00000678140.1 A0A7I2V5C8 |