Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 5244.48 | 459 / 459 | 100% | 55.38 | 1118 / 1118 |
esophagus | 100% | 4516.08 | 1445 / 1445 | 100% | 50.48 | 183 / 183 |
lung | 100% | 5308.11 | 578 / 578 | 100% | 46.50 | 1155 / 1155 |
prostate | 100% | 5141.98 | 245 / 245 | 100% | 39.44 | 502 / 502 |
uterus | 100% | 5449.09 | 170 / 170 | 100% | 52.03 | 459 / 459 |
thymus | 100% | 4898.98 | 653 / 653 | 100% | 44.51 | 604 / 605 |
bladder | 100% | 4780.14 | 21 / 21 | 100% | 43.06 | 503 / 504 |
ovary | 100% | 5132.88 | 180 / 180 | 100% | 28.11 | 429 / 430 |
brain | 100% | 2664.24 | 2631 / 2642 | 100% | 36.10 | 705 / 705 |
pancreas | 100% | 2842.63 | 328 / 328 | 99% | 40.90 | 177 / 178 |
intestine | 100% | 5266.86 | 966 / 966 | 99% | 38.08 | 522 / 527 |
kidney | 100% | 3473.28 | 89 / 89 | 99% | 32.79 | 892 / 901 |
stomach | 100% | 3897.61 | 359 / 359 | 99% | 36.45 | 283 / 286 |
liver | 100% | 3276.40 | 226 / 226 | 98% | 24.31 | 399 / 406 |
skin | 100% | 5837.18 | 1809 / 1809 | 98% | 36.69 | 461 / 472 |
adrenal gland | 100% | 3173.54 | 258 / 258 | 97% | 23.91 | 222 / 230 |
adipose | 100% | 4726.86 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 4645.29 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 49.29 | 29 / 29 |
muscle | 100% | 3134.64 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 6373.21 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 49.10 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 19.05 | 1 / 1 |
heart | 99% | 2478.71 | 853 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 96% | 3705.79 | 892 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 90% | 21.53 | 72 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006974 | Biological process | DNA damage response |
GO_0006470 | Biological process | protein dephosphorylation |
GO_0016607 | Cellular component | nuclear speck |
GO_0005813 | Cellular component | centrosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0030289 | Cellular component | protein phosphatase 4 complex |
GO_0072542 | Molecular function | protein phosphatase activator activity |
Gene name | PPP4R3A |
Protein name | Serine/threonine-protein phosphatase 4 regulatory subunit 3A (SMEK homolog 1) SMEK1 protein SMEK homolog 1 Protein phosphatase 4 regulatory subunit 3A |
Synonyms | PP4R3A MSTP033 KIAA2010 SMEK1 |
Description | FUNCTION: Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphorylated on 'Ser-140' (gamma-H2AX) generated during DNA replication and required for DNA DSB repair. . |
Accessions | ENST00000554390.5 H0YIY8 G3V4R3 H0YJN6 G3V5A2 G3V5Z3 ENST00000555029.5 ENST00000555470.1 G3V231 ENST00000554308.5 Q8N6W1 ENST00000554511.1 ENST00000555462.5 [Q6IN85-4] ENST00000554684.5 [Q6IN85-2] Q6IN85 ENST00000554943.6 [Q6IN85-1] ENST00000557018.5 |