PIH1D1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	13 studies	20% ± 6%	Explore
regulatory T cell	13 studies	20% ± 4%	Explore
natural killer cell	11 studies	20% ± 6%	Explore
CD4-positive, alpha-beta T cell	10 studies	20% ± 5%	Explore
fibroblast	10 studies	21% ± 7%	Explore
CD8-positive, alpha-beta T cell	10 studies	20% ± 4%	Explore
epithelial cell	8 studies	32% ± 17%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	7 studies	18% ± 3%	Explore
pericyte	7 studies	21% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	21% ± 3%	Explore
non-classical monocyte	6 studies	25% ± 10%	Explore
endothelial cell	6 studies	28% ± 10%	Explore
ciliated cell	6 studies	37% ± 9%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	20% ± 3%	Explore
mature NK T cell	5 studies	16% ± 1%	Explore
macrophage	5 studies	22% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	5 studies	19% ± 5%	Explore
naive B cell	5 studies	20% ± 5%	Explore
plasmacytoid dendritic cell	5 studies	24% ± 6%	Explore
memory B cell	5 studies	19% ± 1%	Explore
classical monocyte	4 studies	24% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	20% ± 3%	Explore
exhausted T cell	4 studies	22% ± 6%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	18% ± 2%	Explore
T cell	4 studies	19% ± 4%	Explore
plasma cell	4 studies	26% ± 11%	Explore
immature B cell	4 studies	22% ± 7%	Explore
abnormal cell	4 studies	22% ± 5%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	19% ± 1%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	19% ± 2%	Explore
goblet cell	4 studies	25% ± 7%	Explore
basal cell	4 studies	32% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	21% ± 8%	Explore
gamma-delta T cell	4 studies	28% ± 19%	Explore
conventional dendritic cell	3 studies	33% ± 10%	Explore
hematopoietic precursor cell	3 studies	28% ± 9%	Explore
connective tissue cell	3 studies	23% ± 3%	Explore
myofibroblast cell	3 studies	20% ± 2%	Explore
smooth muscle cell	3 studies	25% ± 6%	Explore
myeloid cell	3 studies	20% ± 5%	Explore
capillary endothelial cell	3 studies	18% ± 3%	Explore
precursor B cell	3 studies	35% ± 7%	Explore
pro-B cell	3 studies	28% ± 4%	Explore
erythroblast	3 studies	28% ± 17%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	20% ± 3%	Explore
dendritic cell	3 studies	35% ± 14%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	31% ± 19%	Explore
enteroendocrine cell	3 studies	27% ± 13%	Explore
intestinal crypt stem cell	3 studies	20% ± 2%	Explore
leukocyte	3 studies	21% ± 5%	Explore
transit amplifying cell	3 studies	25% ± 4%	Explore
mucosal invariant T cell	3 studies	16% ± 0%	Explore
neuron	3 studies	27% ± 14%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	8 studies	20% ± 6%	Explore
lung	5 studies	25% ± 7%	Explore
brain	4 studies	22% ± 5%	Explore
intestine	3 studies	24% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2456.48	1445 / 1445	100%	34.34	183 / 183
liver	100%	1746.27	226 / 226	100%	52.37	406 / 406
pancreas	100%	1413.22	328 / 328	100%	58.67	178 / 178
skin	100%	2764.30	1809 / 1809	100%	59.58	472 / 472
uterus	100%	2476.34	170 / 170	100%	84.33	459 / 459
thymus	100%	2882.24	653 / 653	100%	67.38	604 / 605
brain	100%	2021.09	2637 / 2642	100%	58.16	705 / 705
prostate	100%	2984.36	245 / 245	100%	70.82	501 / 502
ovary	100%	2177.97	180 / 180	100%	40.27	429 / 430
kidney	100%	2481.64	89 / 89	100%	44.78	898 / 901
intestine	100%	2545.83	966 / 966	100%	57.02	525 / 527
lung	100%	2099.76	578 / 578	100%	50.14	1150 / 1155
breast	100%	2562.72	459 / 459	100%	58.33	1113 / 1118
stomach	100%	2055.15	359 / 359	99%	45.07	284 / 286
bladder	100%	2141.29	21 / 21	99%	70.30	500 / 504
adrenal gland	100%	2264.95	258 / 258	99%	49.69	228 / 230
adipose	100%	2301.59	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	47.64	80 / 80
lymph node	0%	0	0 / 0	100%	97.46	29 / 29
muscle	100%	1869.34	803 / 803	0%	0	0 / 0
spleen	100%	2993.75	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	76.46	45 / 45
ureter	0%	0	0 / 0	100%	48.96	1 / 1
blood vessel	100%	2153.29	1333 / 1335	0%	0	0 / 0
heart	98%	1213.95	848 / 861	0%	0	0 / 0
peripheral blood	98%	1962.71	914 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_2001268	Biological process	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO_1903939	Biological process	regulation of TORC2 signaling
GO_0048254	Biological process	snoRNA localization
GO_0030855	Biological process	epithelial cell differentiation
GO_1905669	Biological process	TORC1 complex assembly
GO_0006338	Biological process	chromatin remodeling
GO_0000492	Biological process	box C/D snoRNP assembly
GO_0050821	Biological process	protein stabilization
GO_1901838	Biological process	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I
GO_1904263	Biological process	positive regulation of TORC1 signaling
GO_0071902	Biological process	positive regulation of protein serine/threonine kinase activity
GO_0006364	Biological process	rRNA processing
GO_1902661	Biological process	positive regulation of glucose mediated signaling pathway
GO_0005730	Cellular component	nucleolus
GO_1990062	Cellular component	RPAP3/R2TP/prefoldin-like complex
GO_0070761	Cellular component	pre-snoRNP complex
GO_0097255	Cellular component	R2TP complex
GO_0005737	Cellular component	cytoplasm
GO_1990904	Cellular component	ribonucleoprotein complex
GO_0005634	Cellular component	nucleus
GO_0001165	Molecular function	RNA polymerase I cis-regulatory region sequence-specific DNA binding
GO_0042393	Molecular function	histone binding
GO_0019901	Molecular function	protein kinase binding
GO_0140566	Molecular function	histone reader activity
GO_0051117	Molecular function	ATPase binding
GO_0051219	Molecular function	phosphoprotein binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	PIH1D1
Protein name	PIH1 domain containing 1 PIH1 domain-containing protein 1 (Nucleolar protein 17 homolog) PIH1 domain-containing protein 1
Synonyms	NOP17
Description	FUNCTION: Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles . Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription . Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 . Positively regulates the assembly and activity of the mTORC1 complex . .
Accessions	ENST00000601825.1 ENST00000601053.5 M0R0J2 ENST00000596916.5 M0QXD5 ENST00000598889.5 ENST00000595550.1 M0QZZ1 ENST00000596049.5 [Q9NWS0-1] ENST00000262265.10 [Q9NWS0-1] ENST00000597577.5 ENST00000594845.5 Q9NWS0 M0R1R3 M0QYA2 M0R3A8 M0QZ61 M0QYF4 ENST00000598175.5 ENST00000597415.5 M0QZM3 ENST00000600875.5 M0R2P8 ENST00000596651.5 ENST00000599366.5 M0R028 ENST00000601807.5 M0R2H3 M0R3A4

PIH1D1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review