PCF11 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	24 studies	25% ± 8%	Explore
B cell	23 studies	22% ± 6%	Explore
fibroblast	17 studies	22% ± 8%	Explore
naive B cell	14 studies	21% ± 3%	Explore
memory B cell	14 studies	20% ± 3%	Explore
macrophage	12 studies	25% ± 7%	Explore
T cell	11 studies	22% ± 9%	Explore
classical monocyte	10 studies	22% ± 11%	Explore
microglial cell	10 studies	25% ± 8%	Explore
plasmacytoid dendritic cell	10 studies	22% ± 4%	Explore
natural killer cell	9 studies	20% ± 4%	Explore
smooth muscle cell	9 studies	20% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	20% ± 5%	Explore
CD8-positive, alpha-beta T cell	8 studies	20% ± 5%	Explore
mast cell	8 studies	21% ± 5%	Explore
adipocyte	8 studies	21% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	22% ± 6%	Explore
pericyte	7 studies	23% ± 6%	Explore
monocyte	7 studies	21% ± 6%	Explore
oligodendrocyte	7 studies	25% ± 7%	Explore
CD4-positive, alpha-beta T cell	6 studies	23% ± 6%	Explore
gamma-delta T cell	6 studies	22% ± 5%	Explore
epithelial cell	6 studies	39% ± 20%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	20% ± 3%	Explore
astrocyte	6 studies	27% ± 9%	Explore
endothelial cell of lymphatic vessel	5 studies	23% ± 5%	Explore
type I pneumocyte	5 studies	20% ± 2%	Explore
leukocyte	5 studies	20% ± 4%	Explore
mature NK T cell	5 studies	19% ± 5%	Explore
mucosal invariant T cell	5 studies	18% ± 2%	Explore
myeloid cell	5 studies	24% ± 9%	Explore
ciliated cell	5 studies	25% ± 11%	Explore
basal cell	5 studies	30% ± 9%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	17% ± 1%	Explore
regulatory T cell	5 studies	18% ± 1%	Explore
endothelial cell of vascular tree	5 studies	23% ± 7%	Explore
oligodendrocyte precursor cell	5 studies	26% ± 7%	Explore
non-classical monocyte	4 studies	30% ± 8%	Explore
conventional dendritic cell	4 studies	38% ± 17%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	23% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	22% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	21% ± 9%	Explore
lymphocyte	4 studies	27% ± 8%	Explore
innate lymphoid cell	4 studies	20% ± 4%	Explore
goblet cell	4 studies	24% ± 11%	Explore
T follicular helper cell	4 studies	21% ± 5%	Explore
squamous epithelial cell	3 studies	27% ± 17%	Explore
capillary endothelial cell	3 studies	20% ± 1%	Explore
precursor B cell	3 studies	23% ± 3%	Explore
plasma cell	3 studies	28% ± 8%	Explore
retina horizontal cell	3 studies	19% ± 3%	Explore
retinal pigment epithelial cell	3 studies	31% ± 10%	Explore
GABAergic neuron	3 studies	40% ± 2%	Explore
glutamatergic neuron	3 studies	47% ± 5%	Explore
dendritic cell	3 studies	34% ± 17%	Explore
abnormal cell	3 studies	22% ± 2%	Explore
myofibroblast cell	3 studies	23% ± 5%	Explore
group 3 innate lymphoid cell	3 studies	23% ± 4%	Explore
neuron	3 studies	23% ± 6%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	7 studies	25% ± 13%	Explore
brain	7 studies	31% ± 12%	Explore
lung	5 studies	20% ± 3%	Explore
eye	4 studies	26% ± 5%	Explore
adipose	4 studies	17% ± 1%	Explore
intestine	3 studies	20% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	4891.68	1445 / 1445	100%	13.11	183 / 183
breast	100%	5319.63	459 / 459	100%	22.09	1116 / 1118
prostate	100%	6575.58	245 / 245	100%	21.70	501 / 502
stomach	100%	3968.74	359 / 359	100%	12.99	285 / 286
intestine	100%	5366.59	966 / 966	100%	12.96	525 / 527
lung	100%	6000.36	578 / 578	100%	13.40	1150 / 1155
bladder	100%	5601.62	21 / 21	99%	13.25	501 / 504
thymus	100%	6259.44	653 / 653	99%	16.96	601 / 605
ovary	100%	6330.62	180 / 180	99%	11.69	426 / 430
pancreas	100%	2956.64	327 / 328	99%	15.41	176 / 178
brain	98%	2801.01	2597 / 2642	100%	20.74	705 / 705
uterus	100%	6795.54	170 / 170	98%	13.10	449 / 459
adrenal gland	100%	3980.31	258 / 258	97%	13.63	224 / 230
kidney	100%	3678.15	89 / 89	97%	14.02	871 / 901
skin	100%	6999.45	1809 / 1809	95%	13.28	447 / 472
liver	100%	2064.31	226 / 226	86%	6.49	349 / 406
adipose	100%	5315.05	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	18.63	29 / 29
muscle	100%	4436.72	803 / 803	0%	0	0 / 0
spleen	100%	7352.37	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	10.94	1 / 1
blood vessel	100%	5303.43	1334 / 1335	0%	0	0 / 0
heart	98%	2513.69	847 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	11.90	44 / 45
peripheral blood	95%	3668.22	885 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	86%	9.11	69 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0180010	Biological process	co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway
GO_0006369	Biological process	termination of RNA polymerase II transcription
GO_0005849	Cellular component	mRNA cleavage factor complex
GO_0005654	Cellular component	nucleoplasm
GO_0005737	Cellular component	cytoplasm
GO_0005739	Cellular component	mitochondrion
GO_0005634	Cellular component	nucleus
GO_0000993	Molecular function	RNA polymerase II complex binding
GO_0003729	Molecular function	mRNA binding

IV. Literature review

[source]

Gene name	PCF11
Protein name	Pre-mRNA cleavage complex 2 protein Pcf11 (Pre-mRNA cleavage complex II protein Pcf11) PCF11 protein PCF11 cleavage and polyadenylation factor subunit
Synonyms	KIAA0824
Description	FUNCTION: Component of pre-mRNA cleavage complex II, which promotes transcription termination by RNA polymerase II. .
Accessions	ENST00000533018.1 O94913 E9PQ01 ENST00000298281.8 A0A8I5KX04 E9PNY7 Q0D2H7 ENST00000530304.5 ENST00000690938.1 E9PQF9 ENST00000530660.5 E9PKN0 ENST00000530906.1

PCF11 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review