NUDCD2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
CD8-positive, alpha-beta T cell	11 studies	20% ± 5%	Explore
CD4-positive, alpha-beta T cell	10 studies	24% ± 5%	Explore
regulatory T cell	9 studies	18% ± 3%	Explore
natural killer cell	8 studies	21% ± 6%	Explore
ciliated cell	8 studies	32% ± 12%	Explore
T cell	7 studies	18% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	7 studies	20% ± 6%	Explore
plasmacytoid dendritic cell	7 studies	24% ± 8%	Explore
basal cell	6 studies	27% ± 15%	Explore
B cell	6 studies	21% ± 6%	Explore
endothelial cell	6 studies	27% ± 9%	Explore
epithelial cell	6 studies	40% ± 18%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	20% ± 3%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	21% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	20% ± 3%	Explore
fibroblast	5 studies	26% ± 9%	Explore
hematopoietic precursor cell	4 studies	30% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	18% ± 3%	Explore
erythroblast	4 studies	28% ± 16%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	19% ± 2%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	20% ± 5%	Explore
plasma cell	3 studies	30% ± 15%	Explore
plasmablast	3 studies	50% ± 12%	Explore
conventional dendritic cell	3 studies	33% ± 10%	Explore
exhausted T cell	3 studies	22% ± 5%	Explore
non-classical monocyte	3 studies	20% ± 3%	Explore
smooth muscle cell	3 studies	18% ± 3%	Explore
myofibroblast cell	3 studies	16% ± 1%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	19% ± 2%	Explore
macrophage	3 studies	25% ± 5%	Explore
GABAergic neuron	3 studies	21% ± 4%	Explore
glutamatergic neuron	3 studies	32% ± 11%	Explore
dendritic cell	3 studies	36% ± 11%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	39% ± 23%	Explore
goblet cell	3 studies	23% ± 9%	Explore
intestinal crypt stem cell	3 studies	23% ± 0%	Explore
hematopoietic stem cell	3 studies	17% ± 1%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	23% ± 7%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
lung	6 studies	25% ± 10%	Explore
peripheral blood	5 studies	22% ± 7%	Explore
brain	5 studies	23% ± 8%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1240.17	1445 / 1445	100%	7.67	183 / 183
lung	100%	1172.06	578 / 578	100%	9.47	1155 / 1155
brain	100%	1521.30	2641 / 2642	100%	15.85	705 / 705
prostate	100%	1263.82	245 / 245	100%	12.40	501 / 502
uterus	100%	1246.11	170 / 170	100%	11.50	458 / 459
pancreas	100%	1007.23	327 / 328	100%	8.60	178 / 178
stomach	100%	1018.18	359 / 359	100%	9.05	285 / 286
breast	100%	1446.21	459 / 459	100%	10.51	1113 / 1118
ovary	100%	1205.50	180 / 180	100%	10.59	428 / 430
liver	100%	1250.57	226 / 226	100%	9.03	404 / 406
thymus	100%	1269.05	653 / 653	100%	11.11	602 / 605
intestine	100%	1430.12	966 / 966	99%	10.20	524 / 527
bladder	100%	1258.71	21 / 21	99%	10.15	501 / 504
kidney	100%	1219.36	89 / 89	98%	8.08	886 / 901
adrenal gland	100%	1237.79	258 / 258	97%	7.30	223 / 230
skin	100%	1529.81	1808 / 1809	95%	8.08	450 / 472
adipose	100%	1419.60	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	12.95	29 / 29
spleen	100%	1243.09	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	9.37	45 / 45
ureter	0%	0	0 / 0	100%	4.32	1 / 1
muscle	100%	781.28	802 / 803	0%	0	0 / 0
blood vessel	100%	1168.48	1332 / 1335	0%	0	0 / 0
heart	97%	650.40	838 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	90%	5.09	72 / 80
peripheral blood	62%	696.90	573 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0