NUB1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0032436Biological processpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO_0016567Biological processprotein ubiquitination
GO_0006511Biological processubiquitin-dependent protein catabolic process
GO_0034341Biological processresponse to type II interferon
GO_0034612Biological processresponse to tumor necrosis factor
GO_2000058Biological processregulation of ubiquitin-dependent protein catabolic process
GO_0005730Cellular componentnucleolus
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameNUB1
Protein nameNEDD8 ultimate buster 1 (NEDD8 ultimate buster-1, isoform CRA_d)
Negative regulator of ubiquitin like proteins 1
NEDD8 ultimate buster 1
NEDD8 ultimate buster 1 (Negative regulator of ubiquitin-like proteins 1) (Renal carcinoma antigen NY-REN-18)
SynonymshCG_19587
NYREN18
DescriptionFUNCTION: Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2. .

AccessionsF8WDB6
C9JRT6
ENST00000413040.7 [Q9Y5A7-2]
ENST00000470229.6 [Q9Y5A7-1]
ENST00000480714.1
ENST00000460712.1
ENST00000568733.6 [Q9Y5A7-1]
ENST00000413040
ENST00000468404.5
ENST00000483358.5
F8WDL9
H7C5E1
ENST00000568733
H3BM74
ENST00000470316.5
H7C5N1
Q9Y5A7
H3BM14