Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 3590.05 | 1445 / 1445 | 100% | 34.89 | 183 / 183 |
intestine | 100% | 4316.34 | 966 / 966 | 100% | 47.47 | 527 / 527 |
kidney | 100% | 2816.52 | 89 / 89 | 100% | 43.16 | 901 / 901 |
liver | 100% | 2073.91 | 226 / 226 | 100% | 31.53 | 406 / 406 |
lung | 100% | 3950.57 | 578 / 578 | 100% | 45.45 | 1155 / 1155 |
ovary | 100% | 3780.48 | 180 / 180 | 100% | 44.51 | 430 / 430 |
prostate | 100% | 4056.05 | 245 / 245 | 100% | 47.72 | 502 / 502 |
stomach | 100% | 3065.67 | 359 / 359 | 100% | 46.71 | 286 / 286 |
uterus | 100% | 4035.20 | 170 / 170 | 100% | 43.17 | 459 / 459 |
thymus | 100% | 4310.59 | 653 / 653 | 100% | 58.13 | 604 / 605 |
breast | 100% | 4366.23 | 459 / 459 | 100% | 52.20 | 1116 / 1118 |
bladder | 100% | 3827.05 | 21 / 21 | 100% | 43.19 | 503 / 504 |
pancreas | 100% | 2417.47 | 327 / 328 | 100% | 46.52 | 178 / 178 |
brain | 100% | 2295.21 | 2632 / 2642 | 100% | 43.43 | 705 / 705 |
skin | 100% | 3731.55 | 1809 / 1809 | 99% | 52.05 | 469 / 472 |
adrenal gland | 100% | 3533.69 | 258 / 258 | 99% | 36.34 | 227 / 230 |
adipose | 100% | 4313.55 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 4316.88 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 61.55 | 29 / 29 |
spleen | 100% | 4750.41 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 46.53 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 15.44 | 1 / 1 |
muscle | 100% | 3586.58 | 802 / 803 | 0% | 0 | 0 / 0 |
heart | 99% | 2284.23 | 854 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 98% | 2933.49 | 914 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 95% | 23.40 | 76 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0032436 | Biological process | positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
GO_0016567 | Biological process | protein ubiquitination |
GO_0006511 | Biological process | ubiquitin-dependent protein catabolic process |
GO_0034341 | Biological process | response to type II interferon |
GO_0034612 | Biological process | response to tumor necrosis factor |
GO_2000058 | Biological process | regulation of ubiquitin-dependent protein catabolic process |
GO_0005730 | Cellular component | nucleolus |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005515 | Molecular function | protein binding |
Gene name | NUB1 |
Protein name | NEDD8 ultimate buster 1 (NEDD8 ultimate buster-1, isoform CRA_d) Negative regulator of ubiquitin like proteins 1 NEDD8 ultimate buster 1 NEDD8 ultimate buster 1 (Negative regulator of ubiquitin-like proteins 1) (Renal carcinoma antigen NY-REN-18) |
Synonyms | hCG_19587 NYREN18 |
Description | FUNCTION: Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2. . |
Accessions | F8WDB6 C9JRT6 ENST00000413040.7 [Q9Y5A7-2] ENST00000470229.6 [Q9Y5A7-1] ENST00000480714.1 ENST00000460712.1 ENST00000568733.6 [Q9Y5A7-1] ENST00000413040 ENST00000468404.5 ENST00000483358.5 F8WDL9 H7C5E1 ENST00000568733 H3BM74 ENST00000470316.5 H7C5N1 Q9Y5A7 H3BM14 |