Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 21 studies | 43% ± 15% | |
astrocyte | 19 studies | 46% ± 21% | |
oligodendrocyte precursor cell | 12 studies | 47% ± 17% | |
GABAergic neuron | 10 studies | 53% ± 26% | |
pericyte | 10 studies | 27% ± 9% | |
microglial cell | 10 studies | 28% ± 13% | |
fibroblast | 10 studies | 35% ± 12% | |
oligodendrocyte | 10 studies | 27% ± 13% | |
glutamatergic neuron | 9 studies | 57% ± 26% | |
smooth muscle cell | 9 studies | 30% ± 9% | |
adipocyte | 7 studies | 35% ± 8% | |
endothelial cell of lymphatic vessel | 7 studies | 37% ± 9% | |
cardiac muscle cell | 5 studies | 46% ± 11% | |
mast cell | 5 studies | 22% ± 5% | |
macrophage | 5 studies | 30% ± 10% | |
type I pneumocyte | 5 studies | 33% ± 9% | |
type II pneumocyte | 5 studies | 53% ± 10% | |
Mueller cell | 4 studies | 31% ± 10% | |
T cell | 4 studies | 27% ± 9% | |
epithelial cell | 4 studies | 32% ± 13% | |
goblet cell | 4 studies | 41% ± 24% | |
ciliated cell | 4 studies | 28% ± 10% | |
club cell | 4 studies | 33% ± 14% | |
interneuron | 4 studies | 67% ± 27% | |
neuron | 3 studies | 33% ± 15% | |
GABAergic interneuron | 3 studies | 44% ± 18% | |
CD4-positive, alpha-beta T cell | 3 studies | 18% ± 1% | |
vein endothelial cell | 3 studies | 36% ± 20% | |
amacrine cell | 3 studies | 52% ± 32% | |
retina horizontal cell | 3 studies | 43% ± 14% | |
retinal cone cell | 3 studies | 50% ± 17% | |
retinal rod cell | 3 studies | 38% ± 9% | |
endothelial cell of vascular tree | 3 studies | 39% ± 16% | |
hepatocyte | 3 studies | 46% ± 24% | |
retinal pigment epithelial cell | 3 studies | 42% ± 17% | |
capillary endothelial cell | 3 studies | 38% ± 6% | |
respiratory goblet cell | 3 studies | 33% ± 12% | |
lymphocyte | 3 studies | 31% ± 11% | |
mesothelial cell | 3 studies | 44% ± 7% | |
granule cell | 3 studies | 45% ± 23% | |
mucus secreting cell | 3 studies | 35% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 100% | 2781.98 | 653 / 653 | 98% | 21.00 | 594 / 605 |
brain | 100% | 1388.12 | 2640 / 2642 | 95% | 11.45 | 669 / 705 |
prostate | 98% | 690.91 | 239 / 245 | 94% | 5.96 | 471 / 502 |
stomach | 100% | 1039.61 | 359 / 359 | 88% | 7.73 | 253 / 286 |
intestine | 100% | 2223.95 | 966 / 966 | 88% | 9.47 | 466 / 527 |
kidney | 100% | 1439.81 | 89 / 89 | 87% | 10.53 | 786 / 901 |
pancreas | 99% | 731.31 | 326 / 328 | 87% | 6.83 | 154 / 178 |
adrenal gland | 95% | 837.59 | 244 / 258 | 89% | 10.18 | 205 / 230 |
lung | 99% | 1120.39 | 573 / 578 | 70% | 6.27 | 812 / 1155 |
breast | 99% | 1398.73 | 454 / 459 | 63% | 3.85 | 700 / 1118 |
ovary | 100% | 1759.17 | 180 / 180 | 54% | 2.41 | 233 / 430 |
liver | 93% | 595.91 | 211 / 226 | 55% | 2.66 | 224 / 406 |
uterus | 99% | 1097.85 | 168 / 170 | 48% | 3.09 | 222 / 459 |
bladder | 100% | 1639.76 | 21 / 21 | 46% | 3.85 | 232 / 504 |
esophagus | 85% | 711.21 | 1223 / 1445 | 54% | 4.83 | 99 / 183 |
skin | 71% | 580.96 | 1284 / 1809 | 38% | 1.69 | 177 / 472 |
muscle | 100% | 995.63 | 801 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 651.69 | 240 / 241 | 0% | 0 | 0 / 0 |
adipose | 100% | 1265.49 | 1199 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1314.04 | 1329 / 1335 | 0% | 0 | 0 / 0 |
heart | 95% | 1019.54 | 819 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 53% | 4.34 | 24 / 45 |
eye | 0% | 0 | 0 / 0 | 26% | 1.08 | 21 / 80 |
lymph node | 0% | 0 | 0 / 0 | 17% | 0.59 | 5 / 29 |
peripheral blood | 10% | 37.30 | 93 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_1901224 | Biological process | positive regulation of non-canonical NF-kappaB signal transduction |
GO_0030518 | Biological process | nuclear receptor-mediated steroid hormone signaling pathway |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0007165 | Biological process | signal transduction |
GO_0043235 | Cellular component | receptor complex |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0017025 | Molecular function | TBP-class protein binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0003707 | Molecular function | nuclear steroid receptor activity |
GO_0004879 | Molecular function | nuclear receptor activity |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
GO_0034056 | Molecular function | estrogen response element binding |
GO_0003700 | Molecular function | DNA-binding transcription factor activity |
GO_0008270 | Molecular function | zinc ion binding |
GO_0005496 | Molecular function | steroid binding |
GO_0005515 | Molecular function | protein binding |
Gene name | NR3C2 |
Protein name | Mineralocorticoid receptor 3 (Nuclear receptor subfamily 3, group C, member 2 variant 4) Uncharacterized protein NR3C2 Mineralocorticoid receptor (Nuclear receptor subfamily 3 group C member 2) Mineralocorticoid receptor (MR) (Nuclear receptor subfamily 3 group C member 2) |
Synonyms | MCR MLR |
Description | FUNCTION: Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels. . FUNCTION: Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels. . |
Accessions | B0ZBF6 ENST00000625323.2 [P08235-3] B0ZBF8 P08235 ENST00000344721.8 [P08235-1] ENST00000512865.5 [P08235-4] Q4W5E8 ENST00000342437.8 [P08235-2] ENST00000358102.8 [P08235-1] ENST00000511528.1 [P08235-3] |