Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 25 studies | 37% ± 17% | |
astrocyte | 19 studies | 46% ± 21% | |
microglial cell | 14 studies | 47% ± 12% | |
oligodendrocyte precursor cell | 13 studies | 42% ± 19% | |
fibroblast | 13 studies | 37% ± 15% | |
glutamatergic neuron | 12 studies | 55% ± 27% | |
macrophage | 12 studies | 40% ± 17% | |
oligodendrocyte | 12 studies | 42% ± 15% | |
GABAergic neuron | 11 studies | 49% ± 25% | |
epithelial cell | 9 studies | 36% ± 19% | |
adipocyte | 9 studies | 52% ± 12% | |
smooth muscle cell | 9 studies | 32% ± 10% | |
pericyte | 8 studies | 35% ± 12% | |
myeloid cell | 8 studies | 30% ± 12% | |
endothelial cell of lymphatic vessel | 8 studies | 41% ± 16% | |
neuron | 7 studies | 43% ± 21% | |
dendritic cell | 7 studies | 31% ± 9% | |
mast cell | 7 studies | 25% ± 8% | |
interneuron | 6 studies | 60% ± 24% | |
retinal cone cell | 6 studies | 34% ± 15% | |
ciliated cell | 6 studies | 29% ± 10% | |
T cell | 6 studies | 25% ± 7% | |
type I pneumocyte | 6 studies | 40% ± 14% | |
type II pneumocyte | 6 studies | 40% ± 13% | |
basal cell | 6 studies | 37% ± 24% | |
retina horizontal cell | 5 studies | 37% ± 16% | |
cardiac muscle cell | 5 studies | 51% ± 12% | |
monocyte | 5 studies | 35% ± 10% | |
granule cell | 4 studies | 42% ± 6% | |
CD4-positive, alpha-beta T cell | 4 studies | 22% ± 3% | |
mesothelial cell | 4 studies | 34% ± 10% | |
lymphocyte | 4 studies | 30% ± 15% | |
Mueller cell | 4 studies | 40% ± 18% | |
amacrine cell | 4 studies | 38% ± 12% | |
retinal ganglion cell | 4 studies | 52% ± 24% | |
retinal rod cell | 4 studies | 44% ± 10% | |
hepatocyte | 4 studies | 50% ± 15% | |
club cell | 4 studies | 34% ± 10% | |
natural killer cell | 4 studies | 21% ± 3% | |
goblet cell | 4 studies | 35% ± 28% | |
classical monocyte | 3 studies | 21% ± 5% | |
hematopoietic precursor cell | 3 studies | 29% ± 8% | |
non-classical monocyte | 3 studies | 21% ± 1% | |
GABAergic interneuron | 3 studies | 46% ± 7% | |
glial cell | 3 studies | 29% ± 14% | |
progenitor cell | 3 studies | 40% ± 9% | |
plasma cell | 3 studies | 26% ± 7% | |
CD8-positive, alpha-beta T cell | 3 studies | 20% ± 4% | |
mononuclear phagocyte | 3 studies | 30% ± 8% | |
vein endothelial cell | 3 studies | 43% ± 26% | |
GABAergic amacrine cell | 3 studies | 36% ± 12% | |
OFF-bipolar cell | 3 studies | 40% ± 17% | |
ON-bipolar cell | 3 studies | 36% ± 13% | |
glycinergic amacrine cell | 3 studies | 31% ± 5% | |
endothelial cell of vascular tree | 3 studies | 42% ± 21% | |
retinal pigment epithelial cell | 3 studies | 45% ± 25% | |
connective tissue cell | 3 studies | 28% ± 8% | |
ependymal cell | 3 studies | 53% ± 15% | |
myofibroblast cell | 3 studies | 36% ± 15% | |
B cell | 3 studies | 26% ± 5% | |
alveolar macrophage | 3 studies | 51% ± 9% | |
capillary endothelial cell | 3 studies | 24% ± 5% | |
respiratory goblet cell | 3 studies | 38% ± 14% | |
leukocyte | 3 studies | 47% ± 8% | |
transit amplifying cell | 3 studies | 44% ± 36% | |
mural cell | 3 studies | 39% ± 9% | |
mucus secreting cell | 3 studies | 30% ± 8% | |
regulatory T cell | 3 studies | 19% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 3443.08 | 1445 / 1445 | 100% | 15.51 | 183 / 183 |
lung | 100% | 2890.46 | 578 / 578 | 100% | 11.60 | 1153 / 1155 |
intestine | 100% | 3757.42 | 966 / 966 | 100% | 10.02 | 526 / 527 |
ovary | 100% | 4219.61 | 180 / 180 | 100% | 12.95 | 429 / 430 |
stomach | 100% | 2164.62 | 359 / 359 | 100% | 10.92 | 285 / 286 |
breast | 100% | 3226.70 | 459 / 459 | 99% | 14.16 | 1110 / 1118 |
prostate | 100% | 2817.42 | 245 / 245 | 99% | 10.25 | 498 / 502 |
thymus | 100% | 3558.38 | 653 / 653 | 99% | 15.41 | 599 / 605 |
bladder | 100% | 4342.90 | 21 / 21 | 99% | 11.01 | 499 / 504 |
pancreas | 99% | 1470.48 | 326 / 328 | 99% | 9.30 | 176 / 178 |
uterus | 100% | 4274.51 | 170 / 170 | 98% | 10.92 | 450 / 459 |
kidney | 100% | 2041.56 | 89 / 89 | 97% | 9.79 | 878 / 901 |
brain | 97% | 1687.56 | 2575 / 2642 | 100% | 8.45 | 703 / 705 |
skin | 100% | 3722.11 | 1809 / 1809 | 97% | 10.98 | 458 / 472 |
adrenal gland | 100% | 2517.06 | 257 / 258 | 97% | 9.22 | 224 / 230 |
liver | 99% | 1430.61 | 224 / 226 | 93% | 7.41 | 377 / 406 |
adipose | 100% | 3305.98 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3597.35 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 2280.28 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 5.16 | 1 / 1 |
muscle | 100% | 1992.33 | 801 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 10.34 | 44 / 45 |
lymph node | 0% | 0 | 0 / 0 | 97% | 8.34 | 28 / 29 |
heart | 96% | 2314.56 | 825 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 91% | 6.88 | 73 / 80 |
peripheral blood | 53% | 1081.23 | 490 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0032991 | Cellular component | protein-containing complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0031491 | Molecular function | nucleosome binding |
GO_0003677 | Molecular function | DNA binding |
GO_0003682 | Molecular function | chromatin binding |
GO_0005515 | Molecular function | protein binding |
GO_0042393 | Molecular function | histone binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | MLLT10 |
Protein name | Protein AF-10 (ALL1-fused gene from chromosome 10 protein) MLLT10 histone lysine methyltransferase DOT1L cofactor |
Synonyms | AF10 |
Description | FUNCTION: Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation . . |
Accessions | ENST00000377072.8 [P55197-1] ENST00000430455.2 ENST00000650772.1 ENST00000495130.5 Q5JT35 ENST00000377091.7 [P55197-2] ENST00000462999.5 A0A494C0R2 H0Y5C4 ENST00000307729.12 [P55197-4] A0A494C1P9 P55197 ENST00000377100.8 [P55197-3] ENST00000438473.6 ENST00000650893.1 A0A494C038 ENST00000651097.1 H0Y5P4 ENST00000652497.1 [P55197-3] ENST00000377059.7 [P55197-4] ENST00000621220.4 [P55197-2] ENST00000631589.1 [P55197-4] A0A494C093 ENST00000420525.1 ENST00000651298.1 |