MGAT1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	41 studies	44% ± 13%	Explore
endothelial cell	32 studies	27% ± 10%	Explore
conventional dendritic cell	24 studies	35% ± 14%	Explore
classical monocyte	24 studies	42% ± 9%	Explore
non-classical monocyte	23 studies	46% ± 12%	Explore
monocyte	21 studies	38% ± 11%	Explore
natural killer cell	21 studies	22% ± 4%	Explore
dendritic cell	20 studies	35% ± 14%	Explore
myeloid cell	18 studies	37% ± 15%	Explore
fibroblast	16 studies	24% ± 9%	Explore
capillary endothelial cell	13 studies	27% ± 5%	Explore
regulatory T cell	13 studies	19% ± 3%	Explore
endothelial cell of lymphatic vessel	12 studies	25% ± 11%	Explore
plasmacytoid dendritic cell	12 studies	32% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	23% ± 5%	Explore
endothelial cell of artery	11 studies	33% ± 10%	Explore
vein endothelial cell	11 studies	22% ± 7%	Explore
plasma cell	9 studies	41% ± 14%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	21% ± 5%	Explore
mucosal invariant T cell	9 studies	19% ± 2%	Explore
microglial cell	9 studies	29% ± 11%	Explore
endothelial cell of vascular tree	9 studies	25% ± 6%	Explore
gamma-delta T cell	9 studies	20% ± 4%	Explore
alveolar macrophage	8 studies	39% ± 11%	Explore
mature NK T cell	8 studies	19% ± 3%	Explore
pericyte	8 studies	20% ± 2%	Explore
CD8-positive, alpha-beta T cell	8 studies	20% ± 3%	Explore
mononuclear phagocyte	7 studies	39% ± 13%	Explore
plasmablast	6 studies	44% ± 22%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	20% ± 4%	Explore
leukocyte	6 studies	27% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	19% ± 2%	Explore
neutrophil	6 studies	32% ± 15%	Explore
connective tissue cell	6 studies	26% ± 9%	Explore
T cell	5 studies	17% ± 2%	Explore
innate lymphoid cell	5 studies	24% ± 15%	Explore
epithelial cell	5 studies	34% ± 13%	Explore
basal cell	5 studies	26% ± 8%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	18% ± 2%	Explore
squamous epithelial cell	4 studies	36% ± 21%	Explore
IgG plasma cell	4 studies	22% ± 3%	Explore
inflammatory macrophage	4 studies	34% ± 12%	Explore
intermediate monocyte	4 studies	50% ± 20%	Explore
goblet cell	4 studies	22% ± 3%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	18% ± 3%	Explore
CD4-positive, alpha-beta T cell	3 studies	19% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	18% ± 1%	Explore
hematopoietic precursor cell	3 studies	22% ± 3%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	17% ± 1%	Explore
glomerular endothelial cell	3 studies	23% ± 3%	Explore
extravillous trophoblast	3 studies	40% ± 13%	Explore
lymphocyte	3 studies	22% ± 6%	Explore
smooth muscle cell	3 studies	20% ± 3%	Explore
retina horizontal cell	3 studies	19% ± 4%	Explore
tissue-resident macrophage	3 studies	49% ± 11%	Explore
ciliated cell	3 studies	24% ± 6%	Explore
endothelial cell of sinusoid	3 studies	23% ± 6%	Explore
type I pneumocyte	3 studies	24% ± 6%	Explore
abnormal cell	3 studies	18% ± 2%	Explore
group 3 innate lymphoid cell	3 studies	25% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	17% ± 0%	Explore
enteroendocrine cell	3 studies	24% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	15 studies	23% ± 6%	Explore
lung	11 studies	25% ± 8%	Explore
intestine	4 studies	23% ± 8%	Explore
placenta	4 studies	24% ± 6%	Explore
brain	4 studies	25% ± 4%	Explore
kidney	3 studies	22% ± 4%	Explore
eye	3 studies	18% ± 1%	Explore
breast	3 studies	16% ± 1%	Explore
liver	3 studies	23% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	11370.73	1445 / 1445	100%	35.88	183 / 183
liver	100%	10202.21	226 / 226	100%	50.87	406 / 406
pancreas	100%	8550.18	328 / 328	100%	54.67	178 / 178
skin	100%	11909.35	1809 / 1809	100%	91.55	472 / 472
stomach	100%	8474.85	359 / 359	100%	37.11	286 / 286
thymus	100%	14635.27	653 / 653	100%	53.47	605 / 605
uterus	100%	10336.64	170 / 170	100%	53.54	459 / 459
lung	100%	16029.86	578 / 578	100%	51.07	1152 / 1155
bladder	100%	11726.05	21 / 21	100%	76.69	502 / 504
prostate	100%	10939.67	245 / 245	100%	45.07	500 / 502
kidney	100%	7767.78	89 / 89	100%	53.00	897 / 901
ovary	100%	10025.13	180 / 180	100%	40.15	428 / 430
intestine	100%	9620.24	966 / 966	99%	39.98	523 / 527
breast	100%	15725.27	459 / 459	99%	45.30	1108 / 1118
adrenal gland	100%	8761.64	258 / 258	99%	34.07	227 / 230
brain	97%	4004.85	2561 / 2642	100%	35.70	705 / 705
adipose	100%	17688.86	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	98.48	80 / 80
lymph node	0%	0	0 / 0	100%	99.86	29 / 29
spleen	100%	18939.48	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	61.70	45 / 45
ureter	0%	0	0 / 0	100%	45.25	1 / 1
heart	100%	7720.97	860 / 861	0%	0	0 / 0
blood vessel	100%	10661.49	1333 / 1335	0%	0	0 / 0
peripheral blood	100%	17381.69	927 / 929	0%	0	0 / 0
muscle	97%	4852.15	781 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0018279	Biological process	protein N-linked glycosylation via asparagine
GO_0006487	Biological process	protein N-linked glycosylation
GO_0001701	Biological process	in utero embryonic development
GO_0006049	Biological process	UDP-N-acetylglucosamine catabolic process
GO_0019082	Biological process	viral protein processing
GO_0033116	Cellular component	endoplasmic reticulum-Golgi intermediate compartment membrane
GO_0000139	Cellular component	Golgi membrane
GO_0070062	Cellular component	extracellular exosome
GO_1903561	Cellular component	extracellular vesicle
GO_0005794	Cellular component	Golgi apparatus
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0016020	Cellular component	membrane
GO_0030145	Molecular function	manganese ion binding
GO_0008375	Molecular function	acetylglucosaminyltransferase activity
GO_0003827	Molecular function	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	MGAT1
Protein name	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (GNT-I) (GlcNAc-T I) (EC 2.4.1.101) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I) Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.101) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I) (GNT-I) (GlcNAc-T I)
Synonyms	MGAT GLCT1 GGNT1 GLYT1
Description	FUNCTION: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. . FUNCTION: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. . FUNCTION: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. . FUNCTION: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. . FUNCTION: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. . FUNCTION: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. . FUNCTION: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. . FUNCTION: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. . FUNCTION: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. .
Accessions	ENST00000427865.2 D6RB69 ENST00000514438.1 ENST00000506889.1 ENST00000504671.1 D6RA48 D6RHZ8 D6RD15 ENST00000514283.1 ENST00000502678.1 D6RAK2 D6RF69 D6RBS3 D6R9U2 ENST00000446023.6 ENST00000307826.5 ENST00000512695.1 ENST00000333055.8 P26572 ENST00000506269.1 D6RIS2 ENST00000513431.5 ENST00000393340.7 ENST00000507384.1

MGAT1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review