IGFBP7 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	54 studies	68% ± 22%	Explore
fibroblast	47 studies	71% ± 21%	Explore
pericyte	42 studies	88% ± 16%	Explore
smooth muscle cell	35 studies	78% ± 21%	Explore
endothelial cell of lymphatic vessel	31 studies	84% ± 19%	Explore
natural killer cell	25 studies	35% ± 14%	Explore
ciliated cell	21 studies	71% ± 19%	Explore
astrocyte	20 studies	40% ± 16%	Explore
connective tissue cell	19 studies	59% ± 27%	Explore
basal cell	17 studies	38% ± 22%	Explore
capillary endothelial cell	17 studies	66% ± 21%	Explore
vein endothelial cell	17 studies	80% ± 15%	Explore
endothelial cell of artery	16 studies	64% ± 21%	Explore
myofibroblast cell	16 studies	65% ± 23%	Explore
endothelial cell of vascular tree	15 studies	78% ± 22%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	35% ± 10%	Explore
conventional dendritic cell	12 studies	33% ± 20%	Explore
epithelial cell	11 studies	52% ± 28%	Explore
type I pneumocyte	10 studies	59% ± 19%	Explore
epithelial cell of proximal tubule	9 studies	41% ± 16%	Explore
macrophage	8 studies	26% ± 10%	Explore
classical monocyte	8 studies	27% ± 8%	Explore
kidney loop of Henle epithelial cell	8 studies	67% ± 25%	Explore
renal alpha-intercalated cell	8 studies	72% ± 26%	Explore
mesothelial cell	8 studies	31% ± 15%	Explore
T cell	7 studies	31% ± 10%	Explore
mature NK T cell	7 studies	22% ± 3%	Explore
kidney distal convoluted tubule epithelial cell	7 studies	69% ± 26%	Explore
adipocyte	7 studies	31% ± 16%	Explore
hematopoietic precursor cell	6 studies	43% ± 23%	Explore
podocyte	6 studies	55% ± 30%	Explore
dendritic cell	6 studies	34% ± 16%	Explore
glial cell	6 studies	60% ± 30%	Explore
cardiac muscle cell	6 studies	31% ± 9%	Explore
melanocyte	6 studies	78% ± 11%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	31% ± 8%	Explore
endothelial cell of sinusoid	5 studies	56% ± 31%	Explore
kidney connecting tubule epithelial cell	5 studies	89% ± 19%	Explore
non-classical monocyte	5 studies	23% ± 7%	Explore
abnormal cell	5 studies	44% ± 23%	Explore
renal principal cell	5 studies	71% ± 28%	Explore
hematopoietic stem cell	5 studies	41% ± 12%	Explore
lymphocyte	5 studies	63% ± 25%	Explore
myeloid cell	5 studies	33% ± 13%	Explore
retinal pigment epithelial cell	5 studies	66% ± 21%	Explore
adventitial cell	5 studies	77% ± 15%	Explore
pancreatic A cell	4 studies	64% ± 7%	Explore
type B pancreatic cell	4 studies	37% ± 6%	Explore
progenitor cell	4 studies	44% ± 13%	Explore
parietal epithelial cell	4 studies	79% ± 18%	Explore
innate lymphoid cell	4 studies	24% ± 8%	Explore
Schwann cell	4 studies	63% ± 17%	Explore
secretory cell	4 studies	74% ± 18%	Explore
hepatic stellate cell	3 studies	69% ± 11%	Explore
renal beta-intercalated cell	3 studies	59% ± 29%	Explore
common myeloid progenitor	3 studies	56% ± 15%	Explore
pro-B cell	3 studies	35% ± 13%	Explore
monocyte	3 studies	32% ± 11%	Explore
muscle cell	3 studies	84% ± 5%	Explore
pancreatic ductal cell	3 studies	76% ± 1%	Explore
ependymal cell	3 studies	43% ± 8%	Explore
granulocyte monocyte progenitor cell	3 studies	34% ± 14%	Explore
mast cell	3 studies	24% ± 9%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	15 studies	31% ± 13%	Explore
kidney	11 studies	42% ± 20%	Explore
heart	7 studies	39% ± 9%	Explore
intestine	5 studies	35% ± 15%	Explore
uterus	5 studies	58% ± 14%	Explore
adipose	5 studies	28% ± 8%	Explore
pancreas	4 studies	48% ± 6%	Explore
brain	4 studies	28% ± 9%	Explore
breast	4 studies	33% ± 6%	Explore
peripheral blood	3 studies	28% ± 11%	Explore
esophagus	3 studies	18% ± 2%	Explore
prostate	3 studies	27% ± 8%	Explore
skin	3 studies	37% ± 18%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	56741.39	89 / 89	100%	1223.99	901 / 901
breast	99%	28262.57	454 / 459	96%	370.37	1078 / 1118
prostate	98%	25483.82	239 / 245	98%	355.88	490 / 502
thymus	100%	51507.54	652 / 653	95%	470.53	574 / 605
adrenal gland	98%	17131.51	252 / 258	95%	465.68	218 / 230
lung	99%	25298.92	572 / 578	90%	293.67	1044 / 1155
ovary	89%	16152.02	160 / 180	98%	402.35	420 / 430
bladder	95%	26011.43	20 / 21	87%	303.62	436 / 504
uterus	99%	26830.84	169 / 170	78%	226.80	358 / 459
intestine	83%	16833.39	801 / 966	92%	381.03	486 / 527
esophagus	69%	16283.52	997 / 1445	86%	253.07	158 / 183
pancreas	48%	5239.19	157 / 328	98%	894.03	175 / 178
stomach	47%	8920.55	167 / 359	95%	417.69	273 / 286
skin	57%	7231.57	1039 / 1809	82%	319.02	386 / 472
brain	25%	2310.36	654 / 2642	97%	491.04	686 / 705
liver	42%	4788.92	94 / 226	75%	221.51	306 / 406
blood vessel	100%	157384.16	1335 / 1335	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	117.19	1 / 1
adipose	100%	38558.34	1203 / 1204	0%	0	0 / 0
heart	98%	28902.64	848 / 861	0%	0	0 / 0
spleen	96%	20687.51	231 / 241	0%	0	0 / 0
lymph node	0%	0	0 / 0	86%	166.21	25 / 29
tonsil	0%	0	0 / 0	82%	154.59	37 / 45
eye	0%	0	0 / 0	81%	310.65	65 / 80
muscle	24%	2321.63	195 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0032526	Biological process	response to retinoic acid
GO_0009966	Biological process	regulation of signal transduction
GO_0008285	Biological process	negative regulation of cell population proliferation
GO_0032870	Biological process	cellular response to hormone stimulus
GO_0007155	Biological process	cell adhesion
GO_0001558	Biological process	regulation of cell growth
GO_0051414	Biological process	response to cortisol
GO_0050810	Biological process	regulation of steroid biosynthetic process
GO_0007566	Biological process	embryo implantation
GO_0005615	Cellular component	extracellular space
GO_0005788	Cellular component	endoplasmic reticulum lumen
GO_0070062	Cellular component	extracellular exosome
GO_0005576	Cellular component	extracellular region
GO_0062023	Cellular component	collagen-containing extracellular matrix
GO_0005201	Molecular function	extracellular matrix structural constituent
GO_0005520	Molecular function	insulin-like growth factor binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	IGFBP7
Protein name	Insulin-like growth factor-binding protein 7 (IBP-7) (IGF-binding protein 7) (IGFBP-7) (IGFBP-rP1) (MAC25 protein) (PGI2-stimulating factor) (Prostacyclin-stimulating factor) (Tumor-derived adhesion factor) (TAF)
Synonyms	PSF MAC25
Description	FUNCTION: Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. .
Accessions	ENST00000295666.6 [Q16270-1] Q16270 ENST00000514062.2 [Q16270-2]

IGFBP7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review