HERPUD2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	19 studies	23% ± 7%	Explore
CD8-positive, alpha-beta T cell	18 studies	22% ± 5%	Explore
CD4-positive, alpha-beta T cell	16 studies	22% ± 5%	Explore
gamma-delta T cell	12 studies	28% ± 8%	Explore
T cell	11 studies	21% ± 8%	Explore
mature NK T cell	11 studies	22% ± 4%	Explore
regulatory T cell	10 studies	23% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	30% ± 10%	Explore
B cell	8 studies	20% ± 3%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	24% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	27% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	27% ± 8%	Explore
mucosal invariant T cell	8 studies	31% ± 9%	Explore
astrocyte	8 studies	31% ± 14%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	7 studies	24% ± 6%	Explore
endothelial cell	7 studies	24% ± 9%	Explore
memory B cell	7 studies	19% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	20% ± 6%	Explore
naive B cell	5 studies	21% ± 4%	Explore
macrophage	5 studies	20% ± 4%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	20% ± 4%	Explore
non-classical monocyte	4 studies	24% ± 5%	Explore
epithelial cell	4 studies	31% ± 6%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	27% ± 7%	Explore
T follicular helper cell	4 studies	23% ± 6%	Explore
oligodendrocyte	4 studies	22% ± 4%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	30% ± 6%	Explore
exhausted T cell	3 studies	24% ± 5%	Explore
microglial cell	3 studies	21% ± 1%	Explore
ciliated cell	3 studies	21% ± 2%	Explore
lymphocyte	3 studies	34% ± 10%	Explore
GABAergic neuron	3 studies	47% ± 4%	Explore
glutamatergic neuron	3 studies	47% ± 4%	Explore
oligodendrocyte precursor cell	3 studies	24% ± 7%	Explore
abnormal cell	3 studies	22% ± 2%	Explore
basal cell	3 studies	22% ± 1%	Explore
neuron	3 studies	21% ± 7%	Explore
innate lymphoid cell	3 studies	24% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	20% ± 3%	Explore
interneuron	3 studies	38% ± 21%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	10 studies	21% ± 5%	Explore
brain	5 studies	34% ± 10%	Explore
lung	3 studies	18% ± 2%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	2268.71	459 / 459	100%	35.23	1118 / 1118
esophagus	100%	2020.02	1445 / 1445	100%	34.47	183 / 183
kidney	100%	1383.35	89 / 89	100%	32.76	901 / 901
ovary	100%	3242.94	180 / 180	100%	28.88	430 / 430
pancreas	100%	1675.81	328 / 328	100%	31.91	178 / 178
stomach	100%	1486.52	359 / 359	100%	31.77	286 / 286
uterus	100%	2564.05	170 / 170	100%	28.01	459 / 459
brain	100%	1558.64	2640 / 2642	100%	41.71	705 / 705
lung	100%	2241.32	577 / 578	100%	37.08	1155 / 1155
intestine	100%	2192.45	966 / 966	100%	31.09	526 / 527
bladder	100%	2366.90	21 / 21	100%	30.90	503 / 504
prostate	100%	1829.37	245 / 245	100%	29.50	501 / 502
thymus	100%	1845.02	653 / 653	100%	30.70	603 / 605
liver	100%	1398.23	226 / 226	100%	22.17	404 / 406
skin	100%	2240.14	1809 / 1809	99%	31.30	465 / 472
adrenal gland	100%	1300.19	258 / 258	98%	21.81	226 / 230
adipose	100%	2423.98	1204 / 1204	0%	0	0 / 0
blood vessel	100%	2314.44	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	29.83	29 / 29
spleen	100%	2231.85	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	27.00	45 / 45
ureter	0%	0	0 / 0	100%	9.11	1 / 1
muscle	100%	1119.07	799 / 803	0%	0	0 / 0
heart	99%	1073.82	853 / 861	0%	0	0 / 0
peripheral blood	99%	2120.26	920 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	90%	15.77	72 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0