Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 26 studies | 50% ± 18% | |
astrocyte | 20 studies | 65% ± 22% | |
oligodendrocyte | 16 studies | 67% ± 15% | |
oligodendrocyte precursor cell | 16 studies | 66% ± 22% | |
microglial cell | 14 studies | 45% ± 17% | |
glutamatergic neuron | 13 studies | 79% ± 20% | |
fibroblast | 13 studies | 46% ± 15% | |
smooth muscle cell | 12 studies | 39% ± 15% | |
pericyte | 12 studies | 42% ± 16% | |
GABAergic neuron | 11 studies | 77% ± 18% | |
macrophage | 10 studies | 30% ± 13% | |
adipocyte | 10 studies | 61% ± 18% | |
epithelial cell | 7 studies | 37% ± 24% | |
mesothelial cell | 7 studies | 52% ± 21% | |
endothelial cell of lymphatic vessel | 7 studies | 41% ± 12% | |
neuron | 6 studies | 65% ± 24% | |
interneuron | 6 studies | 83% ± 16% | |
cardiac muscle cell | 6 studies | 57% ± 24% | |
retinal cone cell | 5 studies | 79% ± 29% | |
T cell | 5 studies | 28% ± 11% | |
myeloid cell | 5 studies | 26% ± 7% | |
basal cell | 5 studies | 56% ± 21% | |
club cell | 5 studies | 48% ± 20% | |
type I pneumocyte | 5 studies | 51% ± 8% | |
type II pneumocyte | 5 studies | 71% ± 9% | |
cholangiocyte | 4 studies | 54% ± 24% | |
hepatocyte | 4 studies | 78% ± 17% | |
granule cell | 4 studies | 79% ± 15% | |
B cell | 4 studies | 21% ± 6% | |
capillary endothelial cell | 4 studies | 28% ± 9% | |
dendritic cell | 4 studies | 19% ± 3% | |
Mueller cell | 4 studies | 64% ± 15% | |
amacrine cell | 4 studies | 89% ± 11% | |
retina horizontal cell | 4 studies | 90% ± 10% | |
retinal ganglion cell | 4 studies | 89% ± 11% | |
retinal rod cell | 4 studies | 84% ± 12% | |
monocyte | 4 studies | 28% ± 8% | |
ciliated cell | 4 studies | 34% ± 12% | |
regulatory T cell | 4 studies | 31% ± 12% | |
hepatic stellate cell | 3 studies | 50% ± 24% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 70% ± 5% | |
GABAergic interneuron | 3 studies | 82% ± 15% | |
glial cell | 3 studies | 42% ± 6% | |
progenitor cell | 3 studies | 49% ± 14% | |
plasma cell | 3 studies | 34% ± 13% | |
CD4-positive, alpha-beta T cell | 3 studies | 22% ± 2% | |
endothelial cell of artery | 3 studies | 23% ± 6% | |
vein endothelial cell | 3 studies | 41% ± 11% | |
retinal bipolar neuron | 3 studies | 70% ± 37% | |
GABAergic amacrine cell | 3 studies | 89% ± 11% | |
OFF-bipolar cell | 3 studies | 79% ± 21% | |
ON-bipolar cell | 3 studies | 80% ± 22% | |
glycinergic amacrine cell | 3 studies | 86% ± 8% | |
endothelial cell of vascular tree | 3 studies | 47% ± 8% | |
retinal pigment epithelial cell | 3 studies | 60% ± 25% | |
connective tissue cell | 3 studies | 33% ± 7% | |
ependymal cell | 3 studies | 53% ± 11% | |
alveolar macrophage | 3 studies | 37% ± 7% | |
respiratory goblet cell | 3 studies | 55% ± 20% | |
muscle cell | 3 studies | 50% ± 20% | |
goblet cell | 3 studies | 43% ± 25% | |
leukocyte | 3 studies | 42% ± 17% | |
mucus secreting cell | 3 studies | 47% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 915.90 | 245 / 245 | 100% | 15.25 | 502 / 502 |
brain | 100% | 2673.81 | 2639 / 2642 | 100% | 23.65 | 703 / 705 |
thymus | 100% | 1177.52 | 652 / 653 | 99% | 15.99 | 601 / 605 |
intestine | 100% | 977.24 | 966 / 966 | 99% | 16.08 | 522 / 527 |
pancreas | 99% | 1083.96 | 326 / 328 | 99% | 9.09 | 176 / 178 |
stomach | 100% | 991.46 | 359 / 359 | 98% | 12.97 | 281 / 286 |
esophagus | 100% | 878.27 | 1443 / 1445 | 97% | 13.04 | 178 / 183 |
breast | 100% | 1331.38 | 459 / 459 | 96% | 12.94 | 1078 / 1118 |
uterus | 100% | 1028.07 | 170 / 170 | 96% | 10.37 | 442 / 459 |
skin | 100% | 1275.33 | 1807 / 1809 | 96% | 13.80 | 453 / 472 |
kidney | 100% | 1642.73 | 89 / 89 | 95% | 14.31 | 856 / 901 |
lung | 99% | 921.77 | 573 / 578 | 96% | 9.51 | 1107 / 1155 |
liver | 100% | 2023.52 | 226 / 226 | 95% | 11.86 | 385 / 406 |
adrenal gland | 100% | 993.81 | 258 / 258 | 94% | 10.15 | 216 / 230 |
bladder | 100% | 1006.33 | 21 / 21 | 91% | 10.13 | 459 / 504 |
ovary | 100% | 858.06 | 180 / 180 | 73% | 4.35 | 312 / 430 |
adipose | 100% | 1298.03 | 1204 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 1647.84 | 803 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 11.38 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.38 | 1 / 1 |
blood vessel | 100% | 928.71 | 1333 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 525.05 | 240 / 241 | 0% | 0 | 0 / 0 |
heart | 95% | 814.74 | 821 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 94% | 8.48 | 75 / 80 |
lymph node | 0% | 0 | 0 / 0 | 76% | 5.36 | 22 / 29 |
peripheral blood | 29% | 879.13 | 268 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007529 | Biological process | establishment of synaptic specificity at neuromuscular junction |
GO_0010038 | Biological process | response to metal ion |
GO_0006777 | Biological process | Mo-molybdopterin cofactor biosynthetic process |
GO_0098970 | Biological process | postsynaptic neurotransmitter receptor diffusion trapping |
GO_0032324 | Biological process | molybdopterin cofactor biosynthetic process |
GO_0097112 | Biological process | gamma-aminobutyric acid receptor clustering |
GO_0072579 | Biological process | glycine receptor clustering |
GO_0005856 | Cellular component | cytoskeleton |
GO_0005886 | Cellular component | plasma membrane |
GO_0097060 | Cellular component | synaptic membrane |
GO_0030425 | Cellular component | dendrite |
GO_0005829 | Cellular component | cytosol |
GO_0014069 | Cellular component | postsynaptic density |
GO_0005737 | Cellular component | cytoplasm |
GO_0045211 | Cellular component | postsynaptic membrane |
GO_0099572 | Cellular component | postsynaptic specialization |
GO_0099634 | Cellular component | postsynaptic specialization membrane |
GO_0061599 | Molecular function | molybdopterin molybdotransferase activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0008940 | Molecular function | nitrate reductase activity |
GO_0043546 | Molecular function | molybdopterin cofactor binding |
GO_0046872 | Molecular function | metal ion binding |
GO_0005524 | Molecular function | ATP binding |
GO_0061598 | Molecular function | molybdopterin adenylyltransferase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | GPHN |
Protein name | Gephyrin [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)] molybdopterin molybdotransferase (EC 2.10.1.1) Gephyrin [Includes: Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E); Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G)] Gephyrin |
Synonyms | KIAA1385 GPH |
Description | FUNCTION: Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Acts as a major instructive molecule at inhibitory synapses, where it also clusters GABA type A receptors . .; FUNCTION: Has also a catalytic activity and catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. . FUNCTION: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. . FUNCTION: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. . |
Accessions | ENST00000556240.1 G3V4R0 ENST00000555668.5 ENST00000555456.1 G3V582 G3V4D2 ENST00000555503.1 H0YIY4 ENST00000315266.9 [Q9NQX3-1] ENST00000553936.5 H0YJ30 H0YJR5 ENST00000556633.5 Q9NQX3 ENST00000478722.6 [Q9NQX3-2] ENST00000557654.5 ENST00000543237.5 G3V355 ENST00000459628.5 F5H039 |