GNL3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0017145Biological processstem cell division
GO_0033235Biological processpositive regulation of protein sumoylation
GO_0019827Biological processstem cell population maintenance
GO_0032206Biological processpositive regulation of telomere maintenance
GO_1902895Biological processpositive regulation of miRNA transcription
GO_0042127Biological processregulation of cell population proliferation
GO_1904816Biological processpositive regulation of protein localization to chromosome, telomeric region
GO_0005730Cellular componentnucleolus
GO_0005615Cellular componentextracellular space
GO_0005694Cellular componentchromosome
GO_0016604Cellular componentnuclear body
GO_0030496Cellular componentmidbody
GO_0016020Cellular componentmembrane
GO_0005634Cellular componentnucleus
GO_0005525Molecular functionGTP binding
GO_0048027Molecular functionmRNA 5'-UTR binding
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameGNL3
Protein nameG protein nucleolar 3
G protein nucleolar 3 (cDNA FLJ57535, highly similar to Guanine nucleotide-binding protein-like 3)
Guanine nucleotide-binding protein-like 3 (E2-induced gene 3 protein) (Novel nucleolar protein 47) (NNP47) (Nucleolar GTP-binding protein 3) (Nucleostemin)
SynonymsE2IG3
NS
DescriptionFUNCTION: May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity). .

AccessionsC9JZT7
ENST00000394799.6 [Q9BVP2-2]
ENST00000492349.5
Q9BVP2
ENST00000474423.1
ENST00000479230.5
ENST00000418458.6 [Q9BVP2-1]
B4DMU5
C9JYH9