GIT2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	16 studies	20% ± 5%	Explore
macrophage	16 studies	27% ± 13%	Explore
natural killer cell	14 studies	17% ± 2%	Explore
endothelial cell	13 studies	28% ± 9%	Explore
plasmacytoid dendritic cell	10 studies	24% ± 6%	Explore
microglial cell	9 studies	34% ± 12%	Explore
glutamatergic neuron	8 studies	38% ± 25%	Explore
CD8-positive, alpha-beta T cell	8 studies	18% ± 3%	Explore
myeloid cell	8 studies	27% ± 10%	Explore
dendritic cell	8 studies	28% ± 13%	Explore
CD16-positive, CD56-dim natural killer cell, human	7 studies	18% ± 2%	Explore
classical monocyte	7 studies	28% ± 11%	Explore
non-classical monocyte	7 studies	27% ± 12%	Explore
monocyte	7 studies	26% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	20% ± 4%	Explore
memory B cell	6 studies	17% ± 1%	Explore
naive B cell	6 studies	20% ± 4%	Explore
GABAergic neuron	6 studies	45% ± 22%	Explore
oligodendrocyte	6 studies	23% ± 7%	Explore
CD4-positive, alpha-beta T cell	5 studies	20% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	18% ± 2%	Explore
interneuron	5 studies	40% ± 22%	Explore
oligodendrocyte precursor cell	5 studies	27% ± 10%	Explore
regulatory T cell	5 studies	19% ± 2%	Explore
conventional dendritic cell	4 studies	35% ± 19%	Explore
mature NK T cell	4 studies	17% ± 1%	Explore
epithelial cell	4 studies	24% ± 4%	Explore
immature B cell	4 studies	19% ± 4%	Explore
lymphocyte	4 studies	25% ± 8%	Explore
abnormal cell	4 studies	21% ± 6%	Explore
astrocyte	4 studies	28% ± 6%	Explore
T cell	4 studies	20% ± 2%	Explore
endothelial cell of lymphatic vessel	4 studies	20% ± 1%	Explore
gamma-delta T cell	4 studies	22% ± 7%	Explore
mucosal invariant T cell	4 studies	17% ± 2%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	18% ± 3%	Explore
hematopoietic precursor cell	3 studies	29% ± 7%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	17% ± 1%	Explore
GABAergic interneuron	3 studies	23% ± 2%	Explore
granule cell	3 studies	24% ± 5%	Explore
precursor B cell	3 studies	23% ± 3%	Explore
mononuclear phagocyte	3 studies	27% ± 8%	Explore
alveolar macrophage	3 studies	31% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	20% ± 6%	Explore
double negative thymocyte	3 studies	21% ± 6%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	9 studies	35% ± 18%	Explore
peripheral blood	7 studies	21% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2930.52	1445 / 1445	100%	4.66	183 / 183
stomach	100%	2259.32	358 / 359	100%	4.28	286 / 286
intestine	100%	3447.33	966 / 966	99%	3.25	523 / 527
lung	100%	3484.05	577 / 578	99%	3.94	1148 / 1155
skin	100%	3045.25	1809 / 1809	98%	7.59	463 / 472
breast	100%	3251.87	459 / 459	97%	4.22	1085 / 1118
pancreas	100%	2861.01	327 / 328	97%	3.33	173 / 178
brain	100%	4136.51	2629 / 2642	97%	4.05	684 / 705
thymus	100%	4388.70	653 / 653	96%	3.87	580 / 605
kidney	100%	2595.00	89 / 89	96%	7.10	863 / 901
ovary	100%	3945.58	180 / 180	95%	3.16	410 / 430
bladder	100%	3496.10	21 / 21	95%	2.99	480 / 504
uterus	100%	3431.88	170 / 170	93%	2.80	429 / 459
adrenal gland	100%	4569.71	258 / 258	88%	2.84	203 / 230
prostate	100%	3097.23	245 / 245	88%	2.51	440 / 502
liver	100%	1532.92	226 / 226	67%	1.46	272 / 406
adipose	100%	3659.43	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	6.64	29 / 29
spleen	100%	7628.24	241 / 241	0%	0	0 / 0
blood vessel	100%	3235.24	1334 / 1335	0%	0	0 / 0
heart	99%	2629.71	856 / 861	0%	0	0 / 0
muscle	99%	2014.07	798 / 803	0%	0	0 / 0
peripheral blood	99%	4919.05	919 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	96%	2.98	77 / 80
tonsil	0%	0	0 / 0	91%	3.39	41 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0007420	Biological process	brain development
GO_0036465	Biological process	synaptic vesicle recycling
GO_0008277	Biological process	regulation of G protein-coupled receptor signaling pathway
GO_0032012	Biological process	regulation of ARF protein signal transduction
GO_0098793	Cellular component	presynapse
GO_0005654	Cellular component	nucleoplasm
GO_0045202	Cellular component	synapse
GO_0005925	Cellular component	focal adhesion
GO_0005515	Molecular function	protein binding
GO_0031267	Molecular function	small GTPase binding
GO_0046872	Molecular function	metal ion binding
GO_0005096	Molecular function	GTPase activator activity

IV. Literature review

[source]

Gene name	GIT2
Protein name	ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2) G protein-coupled receptor kinase-interactor 2 isoform 4 G protein-coupled receptor kinase-interactor 2 isoform 4 (GIT2 protein) GIT ArfGAP 2
Synonyms	KIAA0148
Description	FUNCTION: GTPase-activating protein for ADP ribosylation factor family members, including ARF1. .
Accessions	F8VXI9 ENST00000550186.5 ENST00000457474.6 [Q14161-10] ENST00000320063.10 Q6FI58 ENST00000355312.8 [Q14161-1] ENST00000553118.5 [Q14161-11] R4GNG3 ENST00000547815.5 [Q14161-2] B5BU58 F8W822 ENST00000551209.5 ENST00000361006.9 [Q14161-5] Q14161

GIT2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review