FGD3 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	22 studies	21% ± 4%	Explore
CD4-positive, alpha-beta T cell	17 studies	22% ± 6%	Explore
CD8-positive, alpha-beta T cell	15 studies	21% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	23% ± 6%	Explore
T cell	13 studies	19% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	21% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	25% ± 7%	Explore
regulatory T cell	12 studies	21% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	20% ± 5%	Explore
non-classical monocyte	10 studies	23% ± 8%	Explore
mucosal invariant T cell	8 studies	22% ± 3%	Explore
gamma-delta T cell	8 studies	22% ± 3%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	19% ± 3%	Explore
classical monocyte	7 studies	24% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	22% ± 3%	Explore
B cell	7 studies	17% ± 1%	Explore
CD4-positive, alpha-beta memory T cell	6 studies	19% ± 3%	Explore
microglial cell	6 studies	25% ± 8%	Explore
macrophage	6 studies	27% ± 7%	Explore
monocyte	5 studies	22% ± 6%	Explore
naive B cell	5 studies	16% ± 1%	Explore
mature NK T cell	4 studies	24% ± 3%	Explore
lymphocyte	4 studies	33% ± 11%	Explore
T follicular helper cell	4 studies	20% ± 4%	Explore
immature B cell	3 studies	18% ± 3%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	24% ± 4%	Explore
double negative thymocyte	3 studies	20% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	22% ± 2%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	11 studies	20% ± 3%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	2841.14	578 / 578	90%	8.00	1036 / 1155
breast	94%	760.03	430 / 459	95%	41.10	1066 / 1118
pancreas	99%	955.96	325 / 328	89%	11.31	159 / 178
bladder	90%	1470.52	19 / 21	91%	18.22	457 / 504
thymus	99%	1076.67	644 / 653	82%	13.12	495 / 605
kidney	100%	1048.49	89 / 89	77%	6.23	697 / 901
intestine	81%	1200.95	783 / 966	81%	6.13	427 / 527
stomach	79%	434.25	284 / 359	81%	6.26	233 / 286
esophagus	82%	431.47	1181 / 1445	73%	5.14	133 / 183
uterus	59%	263.62	101 / 170	83%	8.55	383 / 459
skin	71%	546.32	1281 / 1809	65%	6.79	309 / 472
prostate	85%	591.93	208 / 245	38%	2.03	191 / 502
brain	28%	114.36	728 / 2642	85%	6.98	599 / 705
liver	78%	378.38	176 / 226	30%	2.67	123 / 406
ovary	37%	138.04	67 / 180	70%	4.07	300 / 430
lymph node	0%	0	0 / 0	100%	49.11	29 / 29
peripheral blood	100%	24579.38	929 / 929	0%	0	0 / 0
spleen	100%	10319.44	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	45.57	1 / 1
adipose	96%	880.91	1160 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	93%	11.54	42 / 45
adrenal gland	69%	318.37	178 / 258	9%	0.47	21 / 230
heart	62%	277.90	536 / 861	0%	0	0 / 0
blood vessel	46%	303.43	616 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	36%	1.88	29 / 80
muscle	4%	12.44	32 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0