ECHDC1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006635Biological processfatty acid beta-oxidation
GO_0005829Cellular componentcytosol
GO_0004492Molecular functionmethyl/ethyl malonyl-CoA decarboxylase activity
GO_0005515Molecular functionprotein binding
GO_0016831Molecular functioncarboxy-lyase activity

IV. Literature review

[source]
Gene nameECHDC1
Protein nameEthylmalonyl-CoA decarboxylase (EC 4.1.1.94) (Enoyl-CoA hydratase domain-containing protein 1) (Methylmalonyl-CoA decarboxylase)
Ethylmalonyl-CoA decarboxylase (EC 4.1.1.94) (Enoyl-CoA hydratase domain-containing protein 1) (Methylmalonyl-CoA decarboxylase) (MMCD)
Ethylmalonyl-CoA decarboxylase 1
Synonyms
DescriptionFUNCTION: Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading . Acts preferentially on (S)-ethylmalonyl-CoA but has also some activity on the (R)-isomer (By similarity). Also has methylmalonyl-CoA decarboxylase activity at lower level (By similarity). .

AccessionsENST00000460558.5
E9PRU6
ENST00000368291.6 [Q9NTX5-5]
E9PPG7
ENST00000526299.5
ENST00000430841.6 [Q9NTX5-2]
H0YCS9
ENST00000454859.8 [Q9NTX5-2]
ENST00000479525.6
ENST00000454591.6 [Q9NTX5-3]
ENST00000525745.5
ENST00000528402.5 [Q9NTX5-4]
ENST00000368292.10
ENST00000436638.6
ENST00000474289.6 [Q9NTX5-2]
H0Y525
ENST00000531967.5 [Q9NTX5-1]
J3KP84
E9PJS8
ENST00000368289.6 [Q9NTX5-5]
ENST00000461239.2
H0Y5L2
ENST00000531582.1
ENST00000417628.6
ENST00000368295.8
Q9NTX5
E9PLY6
F2Z2D6
H0YD54
ENST00000534442.5
E9PIU8