Name | Number of supported studies | Average coverage | |
---|---|---|---|
B cell | 14 studies | 20% ± 5% | |
fibroblast | 13 studies | 21% ± 7% | |
plasmacytoid dendritic cell | 12 studies | 28% ± 10% | |
type I pneumocyte | 10 studies | 28% ± 10% | |
type II pneumocyte | 10 studies | 32% ± 14% | |
endothelial cell | 10 studies | 24% ± 7% | |
macrophage | 10 studies | 23% ± 7% | |
natural killer cell | 9 studies | 18% ± 4% | |
adipocyte | 9 studies | 39% ± 12% | |
classical monocyte | 8 studies | 25% ± 10% | |
conventional dendritic cell | 8 studies | 30% ± 18% | |
memory B cell | 8 studies | 18% ± 2% | |
microglial cell | 7 studies | 26% ± 8% | |
epithelial cell | 7 studies | 36% ± 16% | |
club cell | 7 studies | 29% ± 11% | |
alveolar macrophage | 7 studies | 23% ± 7% | |
naive B cell | 7 studies | 21% ± 4% | |
monocyte | 7 studies | 20% ± 4% | |
non-classical monocyte | 6 studies | 23% ± 8% | |
basal cell | 6 studies | 27% ± 11% | |
ciliated cell | 6 studies | 26% ± 8% | |
oligodendrocyte | 6 studies | 27% ± 7% | |
epithelial cell of proximal tubule | 5 studies | 22% ± 6% | |
GABAergic neuron | 5 studies | 33% ± 13% | |
astrocyte | 5 studies | 29% ± 8% | |
CD8-positive, alpha-beta T cell | 5 studies | 22% ± 6% | |
dendritic cell | 5 studies | 35% ± 16% | |
CD16-negative, CD56-bright natural killer cell, human | 4 studies | 18% ± 2% | |
myeloid cell | 4 studies | 26% ± 8% | |
immature B cell | 4 studies | 21% ± 6% | |
retinal pigment epithelial cell | 4 studies | 24% ± 12% | |
hepatocyte | 4 studies | 31% ± 14% | |
endothelial cell of lymphatic vessel | 4 studies | 22% ± 5% | |
glutamatergic neuron | 4 studies | 49% ± 17% | |
oligodendrocyte precursor cell | 4 studies | 29% ± 7% | |
goblet cell | 4 studies | 18% ± 3% | |
CD4-positive, alpha-beta T cell | 3 studies | 23% ± 5% | |
hematopoietic precursor cell | 3 studies | 24% ± 4% | |
connective tissue cell | 3 studies | 19% ± 4% | |
precursor B cell | 3 studies | 20% ± 3% | |
retinal cone cell | 3 studies | 31% ± 9% | |
retinal rod cell | 3 studies | 19% ± 3% | |
secretory cell | 3 studies | 24% ± 8% | |
abnormal cell | 3 studies | 26% ± 6% | |
intestinal crypt stem cell | 3 studies | 20% ± 3% | |
leukocyte | 3 studies | 21% ± 4% | |
interneuron | 3 studies | 39% ± 16% | |
neuron | 3 studies | 30% ± 6% | |
regulatory T cell | 3 studies | 20% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2488.52 | 1445 / 1445 | 100% | 26.88 | 183 / 183 |
brain | 100% | 2078.90 | 2638 / 2642 | 100% | 33.01 | 705 / 705 |
thymus | 100% | 2688.68 | 653 / 653 | 100% | 36.44 | 604 / 605 |
uterus | 100% | 1893.53 | 170 / 170 | 100% | 35.52 | 458 / 459 |
pancreas | 100% | 1338.88 | 327 / 328 | 100% | 26.94 | 178 / 178 |
stomach | 100% | 2267.82 | 359 / 359 | 100% | 30.19 | 285 / 286 |
bladder | 100% | 3114.33 | 21 / 21 | 100% | 33.87 | 502 / 504 |
lung | 100% | 3443.82 | 578 / 578 | 99% | 32.28 | 1149 / 1155 |
intestine | 100% | 3249.57 | 966 / 966 | 99% | 34.07 | 523 / 527 |
kidney | 100% | 3204.38 | 89 / 89 | 98% | 25.86 | 886 / 901 |
ovary | 100% | 1669.24 | 180 / 180 | 98% | 19.66 | 422 / 430 |
prostate | 100% | 2493.67 | 245 / 245 | 98% | 24.43 | 491 / 502 |
adrenal gland | 100% | 2185.01 | 258 / 258 | 97% | 21.53 | 224 / 230 |
breast | 100% | 3616.03 | 459 / 459 | 96% | 23.87 | 1078 / 1118 |
skin | 100% | 2668.39 | 1808 / 1809 | 96% | 29.60 | 455 / 472 |
liver | 100% | 2445.39 | 226 / 226 | 95% | 23.18 | 385 / 406 |
lymph node | 0% | 0 | 0 / 0 | 100% | 28.27 | 29 / 29 |
spleen | 100% | 2311.16 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 27.85 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 9.38 | 1 / 1 |
adipose | 100% | 4404.93 | 1203 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 1887.52 | 802 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1961.91 | 1330 / 1335 | 0% | 0 | 0 / 0 |
heart | 95% | 1676.65 | 819 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 83% | 1610.08 | 769 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 83% | 14.26 | 66 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006635 | Biological process | fatty acid beta-oxidation |
GO_0005829 | Cellular component | cytosol |
GO_0004492 | Molecular function | methyl/ethyl malonyl-CoA decarboxylase activity |
GO_0005515 | Molecular function | protein binding |
GO_0016831 | Molecular function | carboxy-lyase activity |
Gene name | ECHDC1 |
Protein name | Ethylmalonyl-CoA decarboxylase (EC 4.1.1.94) (Enoyl-CoA hydratase domain-containing protein 1) (Methylmalonyl-CoA decarboxylase) Ethylmalonyl-CoA decarboxylase (EC 4.1.1.94) (Enoyl-CoA hydratase domain-containing protein 1) (Methylmalonyl-CoA decarboxylase) (MMCD) Ethylmalonyl-CoA decarboxylase 1 |
Synonyms | |
Description | FUNCTION: Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading . Acts preferentially on (S)-ethylmalonyl-CoA but has also some activity on the (R)-isomer (By similarity). Also has methylmalonyl-CoA decarboxylase activity at lower level (By similarity). . |
Accessions | ENST00000460558.5 E9PRU6 ENST00000368291.6 [Q9NTX5-5] E9PPG7 ENST00000526299.5 ENST00000430841.6 [Q9NTX5-2] H0YCS9 ENST00000454859.8 [Q9NTX5-2] ENST00000479525.6 ENST00000454591.6 [Q9NTX5-3] ENST00000525745.5 ENST00000528402.5 [Q9NTX5-4] ENST00000368292.10 ENST00000436638.6 ENST00000474289.6 [Q9NTX5-2] H0Y525 ENST00000531967.5 [Q9NTX5-1] J3KP84 E9PJS8 ENST00000368289.6 [Q9NTX5-5] ENST00000461239.2 H0Y5L2 ENST00000531582.1 ENST00000417628.6 ENST00000368295.8 Q9NTX5 E9PLY6 F2Z2D6 H0YD54 ENST00000534442.5 E9PIU8 |