DOCK11 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
macrophage	15 studies	34% ± 20%	Explore
mast cell	12 studies	28% ± 10%	Explore
microglial cell	11 studies	46% ± 16%	Explore
B cell	9 studies	27% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	21% ± 6%	Explore
myeloid cell	9 studies	31% ± 12%	Explore
adipocyte	9 studies	58% ± 16%	Explore
natural killer cell	8 studies	27% ± 9%	Explore
non-classical monocyte	7 studies	23% ± 7%	Explore
dendritic cell	7 studies	31% ± 8%	Explore
interneuron	6 studies	39% ± 16%	Explore
GABAergic neuron	6 studies	43% ± 16%	Explore
monocyte	6 studies	40% ± 12%	Explore
CD4-positive, alpha-beta T cell	5 studies	23% ± 6%	Explore
classical monocyte	5 studies	25% ± 7%	Explore
T cell	5 studies	28% ± 9%	Explore
pericyte	5 studies	25% ± 5%	Explore
alveolar macrophage	5 studies	44% ± 17%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	23% ± 6%	Explore
endothelial cell	4 studies	28% ± 15%	Explore
oligodendrocyte precursor cell	4 studies	21% ± 5%	Explore
CD8-positive, alpha-beta T cell	4 studies	26% ± 6%	Explore
mesothelial cell	4 studies	27% ± 12%	Explore
fibroblast	4 studies	17% ± 1%	Explore
smooth muscle cell	4 studies	19% ± 4%	Explore
type I pneumocyte	4 studies	25% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	22% ± 5%	Explore
hematopoietic precursor cell	3 studies	25% ± 5%	Explore
GABAergic interneuron	3 studies	27% ± 4%	Explore
neuron	3 studies	29% ± 4%	Explore
mononuclear phagocyte	3 studies	30% ± 10%	Explore
lymphocyte	3 studies	41% ± 12%	Explore
glutamatergic neuron	3 studies	36% ± 15%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	18% ± 1%	Explore
regulatory T cell	3 studies	31% ± 6%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	6 studies	27% ± 5%	Explore
peripheral blood	3 studies	24% ± 1%	Explore
lung	3 studies	23% ± 5%	Explore
adipose	3 studies	43% ± 15%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	2721.29	653 / 653	99%	27.54	599 / 605
lung	100%	3512.42	576 / 578	89%	11.35	1028 / 1155
breast	99%	4891.04	456 / 459	89%	10.63	993 / 1118
intestine	96%	2847.86	925 / 966	88%	10.61	464 / 527
esophagus	81%	3095.41	1176 / 1445	90%	12.39	165 / 183
uterus	97%	1987.58	165 / 170	66%	5.50	304 / 459
bladder	95%	2251.00	20 / 21	65%	6.94	328 / 504
skin	79%	1477.13	1425 / 1809	79%	9.40	372 / 472
stomach	65%	1417.86	235 / 359	86%	11.44	246 / 286
kidney	55%	881.87	49 / 89	89%	20.00	801 / 901
adrenal gland	68%	717.47	176 / 258	68%	7.73	156 / 230
brain	26%	287.88	682 / 2642	97%	10.31	684 / 705
prostate	52%	686.00	127 / 245	61%	3.63	307 / 502
blood vessel	100%	4068.06	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	25.61	29 / 29
spleen	100%	3663.52	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	7.45	1 / 1
adipose	100%	7005.47	1203 / 1204	0%	0	0 / 0
peripheral blood	98%	4010.13	907 / 929	0%	0	0 / 0
pancreas	3%	23.64	10 / 328	88%	9.99	156 / 178
tonsil	0%	0	0 / 0	89%	8.37	40 / 45
ovary	33%	384.01	59 / 180	50%	3.80	216 / 430
heart	34%	320.67	294 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	31%	1.76	25 / 80
liver	1%	12.36	3 / 226	27%	1.69	108 / 406
muscle	13%	113.75	106 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0