CHST12 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	35 studies	37% ± 13%	Explore
CD8-positive, alpha-beta T cell	21 studies	26% ± 10%	Explore
mature NK T cell	17 studies	33% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	16 studies	39% ± 13%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	34% ± 12%	Explore
gamma-delta T cell	15 studies	26% ± 6%	Explore
endothelial cell	13 studies	25% ± 11%	Explore
T cell	11 studies	25% ± 8%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	25% ± 6%	Explore
plasma cell	10 studies	30% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	22% ± 8%	Explore
endothelial cell of lymphatic vessel	9 studies	24% ± 8%	Explore
mucosal invariant T cell	7 studies	20% ± 3%	Explore
mast cell	7 studies	30% ± 19%	Explore
plasmacytoid dendritic cell	7 studies	26% ± 7%	Explore
capillary endothelial cell	6 studies	21% ± 3%	Explore
fibroblast	6 studies	23% ± 7%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	24% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	23% ± 11%	Explore
ciliated cell	5 studies	23% ± 5%	Explore
hematopoietic precursor cell	4 studies	27% ± 11%	Explore
plasmablast	4 studies	44% ± 21%	Explore
exhausted T cell	4 studies	30% ± 5%	Explore
lymphocyte	4 studies	27% ± 8%	Explore
vein endothelial cell	3 studies	24% ± 10%	Explore
hematopoietic stem cell	3 studies	23% ± 5%	Explore
connective tissue cell	3 studies	27% ± 6%	Explore
pericyte	3 studies	19% ± 2%	Explore
epithelial cell	3 studies	29% ± 6%	Explore
innate lymphoid cell	3 studies	36% ± 5%	Explore
glutamatergic neuron	3 studies	28% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	24% ± 2%	Explore
astrocyte	3 studies	21% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	8 studies	22% ± 6%	Explore
lung	5 studies	21% ± 3%	Explore
brain	3 studies	23% ± 5%	Explore
liver	3 studies	18% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	1419.81	180 / 180	100%	5.07	430 / 430
prostate	100%	2155.21	245 / 245	100%	5.71	502 / 502
skin	100%	2083.55	1809 / 1809	100%	6.66	472 / 472
thymus	100%	2075.16	653 / 653	100%	5.31	605 / 605
lung	100%	1934.07	578 / 578	100%	6.06	1154 / 1155
esophagus	100%	1383.61	1443 / 1445	100%	5.65	183 / 183
brain	100%	1657.92	2638 / 2642	100%	6.45	705 / 705
uterus	100%	2087.25	170 / 170	100%	5.09	458 / 459
kidney	100%	1505.91	89 / 89	100%	5.83	899 / 901
adrenal gland	100%	1544.87	257 / 258	100%	7.41	230 / 230
pancreas	99%	882.25	326 / 328	100%	5.06	178 / 178
intestine	100%	1588.62	965 / 966	99%	3.89	522 / 527
breast	100%	1883.67	459 / 459	99%	4.53	1106 / 1118
bladder	100%	1664.43	21 / 21	99%	4.93	498 / 504
stomach	100%	1195.65	359 / 359	98%	4.43	280 / 286
liver	94%	579.54	213 / 226	90%	2.16	366 / 406
adipose	100%	1927.07	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	4.57	80 / 80
lymph node	0%	0	0 / 0	100%	5.68	29 / 29
spleen	100%	3381.08	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	4.51	45 / 45
ureter	0%	0	0 / 0	100%	5.13	1 / 1
heart	100%	1374.79	860 / 861	0%	0	0 / 0
blood vessel	100%	1554.63	1332 / 1335	0%	0	0 / 0
muscle	99%	798.23	797 / 803	0%	0	0 / 0
peripheral blood	95%	1837.33	883 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0030208	Biological process	dermatan sulfate biosynthetic process
GO_0030166	Biological process	proteoglycan biosynthetic process
GO_0030206	Biological process	chondroitin sulfate biosynthetic process
GO_0016051	Biological process	carbohydrate biosynthetic process
GO_0000139	Cellular component	Golgi membrane
GO_0016020	Cellular component	membrane
GO_0050656	Molecular function	3'-phosphoadenosine 5'-phosphosulfate binding
GO_0008146	Molecular function	sulfotransferase activity
GO_0047756	Molecular function	chondroitin 4-sulfotransferase activity

IV. Literature review

[source]

Gene name	CHST12
Protein name	Carbohydrate sulfotransferase (EC 2.8.2.-) Carbohydrate sulfotransferase 12 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 2) (Chondroitin 4-sulfotransferase 2) (C4ST-2) (C4ST2) (Sulfotransferase Hlo)
Synonyms	UNQ500/PRO1017
Description	FUNCTION: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Activity toward partially desulfated dermatan sulfate is however lower. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.
Accessions	C9J991 ENST00000432336.1 ENST00000258711.7 Q9NRB3 ENST00000618655.2

CHST12 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review