CHPT1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006656Biological processphosphatidylcholine biosynthetic process
GO_0006629Biological processlipid metabolic process
GO_0001558Biological processregulation of cell growth
GO_0006663Biological processplatelet activating factor biosynthetic process
GO_0006657Biological processCDP-choline pathway
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0000139Cellular componentGolgi membrane
GO_0005794Cellular componentGolgi apparatus
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0004142Molecular functiondiacylglycerol cholinephosphotransferase activity
GO_0019992Molecular functiondiacylglycerol binding
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameCHPT1
Protein nameCholine phosphotransferase 1
Cholinephosphotransferase 1 (hCPT1) (EC 2.7.8.2) (AAPT1-like protein) (Diacylglycerol cholinephosphotransferase 1)
Cholinephosphotransferase 1 (EC 2.7.8.2) (Diacylglycerol cholinephosphotransferase 1)
SynonymsMSTP022
CPT1
DescriptionFUNCTION: Catalyzes the final step of de novo phosphatidylcholine (PC) synthesis, i.e. the transfer of choline phosphate from CDP-choline to the free hydroxyl of a diacylglycerol (DAG), producing a PC. It thereby plays a central role in the formation and maintenance of vesicular membranes. .

AccessionsH0YI84
H0YHV7
ENST00000549128.5
ENST00000229266.8 [Q8WUD6-1]
ENST00000549872.5
H0YI24
Q8WUD6
ENST00000546873.1
F8W1B3
ENST00000552329.1
ENST00000552215.5
ENST00000552351.5 [Q8WUD6-2]