Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| B cell | 9 studies | 21% ± 3% | |
| CD4-positive, alpha-beta T cell | 9 studies | 25% ± 6% | |
| naive B cell | 7 studies | 19% ± 3% | |
| regulatory T cell | 7 studies | 19% ± 5% | |
| naive thymus-derived CD4-positive, alpha-beta T cell | 6 studies | 24% ± 7% | |
| T follicular helper cell | 5 studies | 17% ± 2% | |
| T cell | 3 studies | 20% ± 2% | |
| naive thymus-derived CD8-positive, alpha-beta T cell | 3 studies | 22% ± 8% | |
| epithelial cell | 3 studies | 23% ± 3% |
Insufficient scRNA-seq data for expression of CHMP7 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 2400.98 | 459 / 459 | 100% | 41.00 | 1118 / 1118 |
| esophagus | 100% | 2907.98 | 1445 / 1445 | 100% | 23.95 | 183 / 183 |
| intestine | 100% | 3512.89 | 966 / 966 | 100% | 29.41 | 527 / 527 |
| lung | 100% | 2401.63 | 578 / 578 | 100% | 31.95 | 1155 / 1155 |
| pancreas | 100% | 1294.87 | 328 / 328 | 100% | 36.26 | 178 / 178 |
| prostate | 100% | 2822.29 | 245 / 245 | 100% | 32.83 | 502 / 502 |
| stomach | 100% | 2187.21 | 359 / 359 | 100% | 28.46 | 286 / 286 |
| uterus | 100% | 2767.15 | 170 / 170 | 100% | 34.66 | 459 / 459 |
| thymus | 100% | 2386.56 | 653 / 653 | 100% | 42.42 | 604 / 605 |
| kidney | 100% | 2160.88 | 89 / 89 | 100% | 30.42 | 899 / 901 |
| brain | 100% | 2109.20 | 2636 / 2642 | 100% | 42.19 | 705 / 705 |
| skin | 100% | 2434.77 | 1809 / 1809 | 100% | 45.53 | 470 / 472 |
| liver | 100% | 1424.87 | 226 / 226 | 100% | 17.91 | 404 / 406 |
| bladder | 100% | 2979.48 | 21 / 21 | 99% | 29.54 | 501 / 504 |
| adrenal gland | 100% | 3647.57 | 258 / 258 | 99% | 35.66 | 228 / 230 |
| ovary | 100% | 2259.33 | 180 / 180 | 99% | 17.93 | 425 / 430 |
| adipose | 100% | 2304.62 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 2506.73 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 77.46 | 29 / 29 |
| muscle | 100% | 2583.32 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 5110.76 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 38.90 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 15.34 | 1 / 1 |
| heart | 99% | 2313.72 | 854 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 26.50 | 79 / 80 |
| peripheral blood | 97% | 1867.04 | 901 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0001778 | Biological process | plasma membrane repair |
| GO_0051469 | Biological process | vesicle fusion with vacuole |
| GO_0039702 | Biological process | viral budding via host ESCRT complex |
| GO_0036258 | Biological process | multivesicular body assembly |
| GO_0061763 | Biological process | multivesicular body-lysosome fusion |
| GO_1901673 | Biological process | regulation of mitotic spindle assembly |
| GO_0045324 | Biological process | late endosome to vacuole transport |
| GO_0043162 | Biological process | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway |
| GO_0061952 | Biological process | midbody abscission |
| GO_0090148 | Biological process | membrane fission |
| GO_0006997 | Biological process | nucleus organization |
| GO_0032511 | Biological process | late endosome to vacuole transport via multivesicular body sorting pathway |
| GO_0046761 | Biological process | viral budding from plasma membrane |
| GO_0010458 | Biological process | exit from mitosis |
| GO_1902774 | Biological process | late endosome to lysosome transport |
| GO_0071985 | Biological process | multivesicular body sorting pathway |
| GO_0006900 | Biological process | vesicle budding from membrane |
| GO_0071168 | Biological process | protein localization to chromatin |
| GO_1904903 | Biological process | ESCRT III complex disassembly |
| GO_0015031 | Biological process | protein transport |
| GO_0006914 | Biological process | autophagy |
| GO_0097352 | Biological process | autophagosome maturation |
| GO_0007080 | Biological process | mitotic metaphase chromosome alignment |
| GO_0031468 | Biological process | nuclear membrane reassembly |
| GO_0000815 | Cellular component | ESCRT III complex |
| GO_0030496 | Cellular component | midbody |
| GO_0005643 | Cellular component | nuclear pore |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0009898 | Cellular component | cytoplasmic side of plasma membrane |
| GO_0000776 | Cellular component | kinetochore |
| GO_0000421 | Cellular component | autophagosome membrane |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005635 | Cellular component | nuclear envelope |
| GO_0005829 | Cellular component | cytosol |
| GO_0005828 | Cellular component | kinetochore microtubule |
| GO_0005771 | Cellular component | multivesicular body |
| GO_1904930 | Cellular component | amphisome membrane |
| GO_0000785 | Cellular component | chromatin |
| GO_0032585 | Cellular component | multivesicular body membrane |
| GO_0005765 | Cellular component | lysosomal membrane |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CHMP7 |
| Protein name | Charged multivesicular body protein 7 (Chromatin-modifying protein 7) Charged multivesicular body protein 7 |
| Synonyms | |
| Description | FUNCTION: ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope (NE) during late anaphase . Together with SPAST, the ESCRT-III complex promotes NE sealing and mitotic spindle disassembly during late anaphase . Recruited to the reforming NE during anaphase by LEMD2 . Plays a role in the endosomal sorting pathway . . |
| Accessions | E5RIU9 ENST00000519984.1 ENST00000519503.5 [Q8WUX9-2] E5RFR8 E5RJI3 ENST00000313219.8 [Q8WUX9-1] ENST00000517325.5 ENST00000397677.6 [Q8WUX9-1] ENST00000519414.5 Q8WUX9 |
