BID report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0090200Biological processpositive regulation of release of cytochrome c from mitochondria
GO_0006919Biological processactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO_2001238Biological processpositive regulation of extrinsic apoptotic signaling pathway
GO_0042129Biological processregulation of T cell proliferation
GO_2001244Biological processpositive regulation of intrinsic apoptotic signaling pathway
GO_0008625Biological processextrinsic apoptotic signaling pathway via death domain receptors
GO_2000045Biological processregulation of G1/S transition of mitotic cell cycle
GO_0065003Biological processprotein-containing complex assembly
GO_0031334Biological processpositive regulation of protein-containing complex assembly
GO_0097345Biological processmitochondrial outer membrane permeabilization
GO_2000271Biological processpositive regulation of fibroblast apoptotic process
GO_0051402Biological processneuron apoptotic process
GO_0008637Biological processapoptotic mitochondrial changes
GO_0097435Biological processsupramolecular fiber organization
GO_0090150Biological processestablishment of protein localization to membrane
GO_0050678Biological processregulation of epithelial cell proliferation
GO_0097284Biological processhepatocyte apoptotic process
GO_1902230Biological processnegative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO_0001836Biological processrelease of cytochrome c from mitochondria
GO_0042775Biological processmitochondrial ATP synthesis coupled electron transport
GO_0006626Biological processprotein targeting to mitochondrion
GO_0010918Biological processpositive regulation of mitochondrial membrane potential
GO_0043065Biological processpositive regulation of apoptotic process
GO_0042770Biological processsignal transduction in response to DNA damage
GO_0016020Cellular componentmembrane
GO_0005739Cellular componentmitochondrion
GO_0005829Cellular componentcytosol
GO_0005741Cellular componentmitochondrial outer membrane
GO_0031625Molecular functionubiquitin protein ligase binding
GO_0005123Molecular functiondeath receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameBID
Protein nameBH3 interacting domain death agonist Si6 isoform
BH3-interacting domain death agonist (p22 BID) (BID) [Cleaved into: BH3-interacting domain death agonist p15 (p15 BID); BH3-interacting domain death agonist p13 (p13 BID); BH3-interacting domain death agonist p11 (p11 BID)]
BID isoform Si6
BH3-interacting domain death agonist
SynonymshCG_21529
DescriptionFUNCTION: Induces caspases and apoptosis . Counters the protective effect of BCL2 (By similarity). .; FUNCTION: [BH3-interacting domain death agonist p15]: Induces caspase activation and apoptosis . Allows the release of cytochrome c . .; FUNCTION: [Isoform 1]: Induces ICE-like proteases and apoptosis. .; FUNCTION: [Isoform 2]: Induces ICE-like proteases and apoptosis. .; FUNCTION: [Isoform 3]: Does not induce apoptosis. .; FUNCTION: [Isoform 4]: Induces ICE-like proteases and apoptosis. .

FUNCTION: Induces caspases and apoptosis. Counters the protective effect of BCL2. .

AccessionsENST00000342111.9 [P55957-3]
B2ZP79
A8ASI8
ENST00000399767.6 [P55957-4]
A0A2P1N6T5
P55957
ENST00000622694.5 [P55957-1]
ENST00000551952.5 [P55957-1]
A0A2P1N6U0
B2ZP78
ENST00000614949.4 [P55957-4]
ENST00000399765.5 [P55957-4]
ENST00000317361.11 [P55957-2]
A0A2U9F3W7