mitochondrial outer membrane permeabilization

I. Literature review

[source]
Namemitochondrial outer membrane permeabilization
IDGO_0097345
collection_id

Biological process

Exact synonym

MOMP, mitochondrion outer membrane permeabilization

Description

The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway.

Comment

BAX and BAK are involved in this process, as reviewed in PMID:21760595 (the human proteins have UniProt symbols Q07812 and Q16611 respectively).

External URL
Genes