ATF7IP2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	17 studies	25% ± 9%	Explore
ciliated cell	14 studies	27% ± 8%	Explore
endothelial cell	13 studies	28% ± 8%	Explore
CD4-positive, alpha-beta T cell	11 studies	26% ± 8%	Explore
microglial cell	11 studies	29% ± 10%	Explore
mucosal invariant T cell	11 studies	28% ± 8%	Explore
naive B cell	10 studies	19% ± 4%	Explore
glutamatergic neuron	9 studies	38% ± 25%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	23% ± 8%	Explore
memory B cell	8 studies	19% ± 3%	Explore
CD8-positive, alpha-beta T cell	7 studies	25% ± 5%	Explore
conventional dendritic cell	7 studies	29% ± 19%	Explore
epithelial cell	7 studies	28% ± 10%	Explore
type I pneumocyte	7 studies	53% ± 24%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	31% ± 8%	Explore
fibroblast	6 studies	29% ± 14%	Explore
regulatory T cell	6 studies	26% ± 18%	Explore
astrocyte	6 studies	32% ± 13%	Explore
T cell	6 studies	28% ± 11%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	20% ± 6%	Explore
cardiac muscle cell	5 studies	35% ± 7%	Explore
macrophage	5 studies	30% ± 18%	Explore
natural killer cell	5 studies	28% ± 18%	Explore
hepatocyte	5 studies	51% ± 22%	Explore
GABAergic neuron	5 studies	39% ± 19%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	31% ± 13%	Explore
endothelial cell of lymphatic vessel	4 studies	36% ± 20%	Explore
endothelial cell of vascular tree	4 studies	33% ± 21%	Explore
hematopoietic stem cell	4 studies	21% ± 3%	Explore
adipocyte	4 studies	20% ± 1%	Explore
plasmacytoid dendritic cell	4 studies	22% ± 4%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	23% ± 3%	Explore
gamma-delta T cell	4 studies	26% ± 12%	Explore
plasmablast	3 studies	35% ± 12%	Explore
precursor B cell	3 studies	21% ± 3%	Explore
mesothelial cell	3 studies	31% ± 8%	Explore
myeloid cell	3 studies	18% ± 2%	Explore
Mueller cell	3 studies	19% ± 3%	Explore
basal cell	3 studies	43% ± 10%	Explore
dendritic cell	3 studies	49% ± 15%	Explore
mast cell	3 studies	30% ± 4%	Explore
monocyte	3 studies	42% ± 22%	Explore
oligodendrocyte precursor cell	3 studies	30% ± 6%	Explore
club cell	3 studies	20% ± 2%	Explore
type II pneumocyte	3 studies	26% ± 9%	Explore
lymphocyte	3 studies	32% ± 5%	Explore
interneuron	3 studies	43% ± 18%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	7 studies	21% ± 8%	Explore
brain	6 studies	36% ± 20%	Explore
lung	5 studies	28% ± 7%	Explore
heart	4 studies	22% ± 3%	Explore
liver	3 studies	41% ± 13%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	1629.46	226 / 226	96%	8.96	391 / 406
pancreas	100%	842.48	328 / 328	94%	7.52	168 / 178
ovary	99%	424.59	179 / 180	95%	7.17	408 / 430
bladder	100%	1168.48	21 / 21	90%	10.09	453 / 504
thymus	100%	687.24	653 / 653	88%	6.22	533 / 605
lung	99%	504.23	575 / 578	87%	5.24	1001 / 1155
stomach	100%	620.53	359 / 359	85%	6.44	243 / 286
intestine	100%	522.48	966 / 966	84%	5.59	443 / 527
esophagus	99%	286.85	1425 / 1445	85%	7.46	156 / 183
uterus	99%	352.64	169 / 170	82%	5.56	376 / 459
breast	100%	360.64	458 / 459	80%	5.18	893 / 1118
adrenal gland	100%	1965.59	258 / 258	73%	3.60	167 / 230
kidney	100%	493.24	89 / 89	70%	2.77	631 / 901
prostate	100%	375.53	244 / 245	42%	1.77	210 / 502
skin	74%	226.07	1338 / 1809	54%	3.39	257 / 472
brain	98%	408.85	2576 / 2642	16%	0.55	112 / 705
spleen	100%	1295.96	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	22.71	1 / 1
heart	100%	768.64	860 / 861	0%	0	0 / 0
adipose	95%	355.19	1147 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	93%	9.75	27 / 29
blood vessel	89%	250.57	1190 / 1335	0%	0	0 / 0
peripheral blood	86%	474.31	796 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	78%	5.25	35 / 45
eye	0%	0	0 / 0	65%	2.76	52 / 80
muscle	19%	26.18	155 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0090309	Biological process	positive regulation of DNA methylation-dependent heterochromatin formation
GO_0006355	Biological process	regulation of DNA-templated transcription
GO_0005667	Cellular component	transcription regulator complex
GO_0005634	Cellular component	nucleus
GO_0003712	Molecular function	transcription coregulator activity

IV. Literature review

[source]

Gene name	ATF7IP2
Protein name	Activating transcription factor 7-interacting protein 2 (ATF7-interacting protein 2) (MBD1-containing chromatin-associated factor 2) Activating transcription factor 7-interacting protein 2 Activating transcription factor 7 interacting protein 2
Synonyms	MCAF2
Description	FUNCTION: Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (Probable). .
Accessions	ENST00000562102.6 [Q5U623-1] Q5U623 ENST00000396559.5 [Q5U623-2] ENST00000562102 H3BR07 ENST00000569939.5 I3L4M8 ENST00000562527.5 H3BPC9 B4DKH3 ENST00000535850.5 ENST00000324570.9 [Q5U623-2] ENST00000543967.5 H3BUP1 H3BNE6 ENST00000396560.6 [Q5U623-1] ENST00000356427.2 [Q5U623-1] ENST00000569900.5 ENST00000568027.5 F5GY73

ATF7IP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review