ARHGEF6 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
mast cell	25 studies	39% ± 18%	Explore
microglial cell	10 studies	35% ± 13%	Explore
astrocyte	9 studies	30% ± 14%	Explore
regulatory T cell	9 studies	20% ± 4%	Explore
oligodendrocyte precursor cell	8 studies	31% ± 13%	Explore
natural killer cell	7 studies	17% ± 2%	Explore
macrophage	7 studies	27% ± 8%	Explore
CD4-positive, alpha-beta T cell	7 studies	20% ± 4%	Explore
dendritic cell	6 studies	25% ± 10%	Explore
endothelial cell	5 studies	27% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	19% ± 3%	Explore
T cell	5 studies	22% ± 4%	Explore
GABAergic neuron	4 studies	27% ± 8%	Explore
classical monocyte	4 studies	26% ± 6%	Explore
hematopoietic precursor cell	4 studies	30% ± 11%	Explore
myeloid cell	4 studies	17% ± 2%	Explore
cardiac muscle cell	4 studies	18% ± 3%	Explore
lymphocyte	4 studies	23% ± 10%	Explore
adipocyte	4 studies	37% ± 12%	Explore
CD8-positive, alpha-beta T cell	4 studies	20% ± 4%	Explore
gamma-delta T cell	4 studies	24% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	17% ± 0%	Explore
non-classical monocyte	3 studies	23% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	18% ± 1%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	16% ± 1%	Explore
glutamatergic neuron	3 studies	33% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	17% ± 1%	Explore
leukocyte	3 studies	27% ± 9%	Explore
monocyte	3 studies	20% ± 2%	Explore
smooth muscle cell	3 studies	18% ± 0%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	16% ± 0%	Explore
double negative thymocyte	3 studies	19% ± 4%	Explore
mucosal invariant T cell	3 studies	23% ± 2%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	19% ± 2%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	5 studies	25% ± 4%	Explore
peripheral blood	3 studies	22% ± 4%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	5243.11	459 / 459	97%	41.43	1086 / 1118
brain	95%	2860.70	2504 / 2642	100%	124.84	705 / 705
adrenal gland	100%	3292.08	258 / 258	94%	21.16	217 / 230
kidney	94%	1425.93	84 / 89	89%	23.98	803 / 901
lung	100%	4456.38	577 / 578	79%	12.88	907 / 1155
skin	94%	1586.29	1692 / 1809	77%	22.93	364 / 472
prostate	98%	1898.69	240 / 245	63%	7.08	316 / 502
bladder	100%	2250.19	21 / 21	61%	9.63	305 / 504
thymus	96%	1483.73	629 / 653	62%	11.34	374 / 605
uterus	99%	2872.39	168 / 170	54%	7.67	249 / 459
stomach	94%	1455.89	337 / 359	58%	8.76	166 / 286
intestine	99%	2975.09	959 / 966	44%	5.90	231 / 527
esophagus	86%	1693.26	1244 / 1445	50%	6.28	92 / 183
ovary	100%	2753.08	180 / 180	35%	3.40	149 / 430
adipose	100%	5578.40	1204 / 1204	0%	0	0 / 0
blood vessel	100%	3446.47	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	39.90	29 / 29
muscle	100%	4785.13	803 / 803	0%	0	0 / 0
spleen	100%	6435.06	241 / 241	0%	0	0 / 0
pancreas	20%	163.62	65 / 328	79%	12.87	141 / 178
heart	99%	3705.44	851 / 861	0%	0	0 / 0
peripheral blood	98%	3905.21	913 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	71%	11.81	32 / 45
liver	29%	235.70	66 / 226	27%	2.99	111 / 406
eye	0%	0	0 / 0	34%	2.89	27 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1