Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 47 studies | 42% ± 20% | |
pericyte | 29 studies | 37% ± 19% | |
smooth muscle cell | 21 studies | 30% ± 13% | |
fibroblast | 20 studies | 31% ± 14% | |
astrocyte | 19 studies | 51% ± 22% | |
capillary endothelial cell | 15 studies | 29% ± 15% | |
endothelial cell of lymphatic vessel | 14 studies | 38% ± 18% | |
glutamatergic neuron | 13 studies | 57% ± 25% | |
microglial cell | 13 studies | 30% ± 15% | |
ciliated cell | 12 studies | 28% ± 12% | |
GABAergic neuron | 11 studies | 51% ± 24% | |
endothelial cell of artery | 11 studies | 30% ± 11% | |
oligodendrocyte precursor cell | 11 studies | 38% ± 16% | |
basal cell | 11 studies | 34% ± 19% | |
epithelial cell | 10 studies | 40% ± 22% | |
oligodendrocyte | 10 studies | 26% ± 11% | |
type I pneumocyte | 9 studies | 32% ± 12% | |
vein endothelial cell | 9 studies | 30% ± 22% | |
neuron | 8 studies | 44% ± 19% | |
amacrine cell | 8 studies | 46% ± 15% | |
adipocyte | 8 studies | 26% ± 8% | |
endothelial cell of vascular tree | 8 studies | 32% ± 21% | |
type II pneumocyte | 7 studies | 37% ± 9% | |
macrophage | 7 studies | 32% ± 11% | |
retinal ganglion cell | 7 studies | 43% ± 18% | |
retinal cone cell | 7 studies | 38% ± 15% | |
hepatocyte | 6 studies | 51% ± 28% | |
interneuron | 6 studies | 63% ± 21% | |
club cell | 6 studies | 38% ± 11% | |
retina horizontal cell | 6 studies | 38% ± 16% | |
podocyte | 5 studies | 64% ± 20% | |
retinal bipolar neuron | 5 studies | 41% ± 15% | |
myofibroblast cell | 5 studies | 27% ± 14% | |
cardiac muscle cell | 5 studies | 49% ± 16% | |
Mueller cell | 5 studies | 36% ± 16% | |
respiratory goblet cell | 5 studies | 34% ± 11% | |
secretory cell | 4 studies | 25% ± 8% | |
squamous epithelial cell | 4 studies | 37% ± 21% | |
cholangiocyte | 4 studies | 49% ± 23% | |
granule cell | 4 studies | 42% ± 4% | |
kidney loop of Henle epithelial cell | 4 studies | 23% ± 4% | |
retinal pigment epithelial cell | 4 studies | 43% ± 26% | |
mesothelial cell | 4 studies | 34% ± 9% | |
lymphocyte | 4 studies | 27% ± 6% | |
OFF-bipolar cell | 4 studies | 42% ± 17% | |
ON-bipolar cell | 4 studies | 42% ± 17% | |
retinal rod cell | 4 studies | 37% ± 9% | |
mast cell | 4 studies | 23% ± 6% | |
muscle cell | 4 studies | 38% ± 27% | |
erythrocyte | 4 studies | 47% ± 28% | |
goblet cell | 4 studies | 38% ± 30% | |
ionocyte | 3 studies | 26% ± 9% | |
glomerular endothelial cell | 3 studies | 32% ± 2% | |
GABAergic interneuron | 3 studies | 57% ± 6% | |
glial cell | 3 studies | 32% ± 4% | |
progenitor cell | 3 studies | 31% ± 3% | |
platelet | 3 studies | 20% ± 2% | |
GABAergic amacrine cell | 3 studies | 59% ± 14% | |
glycinergic amacrine cell | 3 studies | 51% ± 11% | |
rod bipolar cell | 3 studies | 54% ± 16% | |
abnormal cell | 3 studies | 29% ± 15% | |
connective tissue cell | 3 studies | 30% ± 9% | |
ependymal cell | 3 studies | 47% ± 19% | |
megakaryocyte | 3 studies | 34% ± 10% | |
enteroendocrine cell | 3 studies | 21% ± 2% | |
Schwann cell | 3 studies | 39% ± 22% | |
epithelial cell of proximal tubule | 3 studies | 24% ± 8% | |
kidney distal convoluted tubule epithelial cell | 3 studies | 25% ± 7% | |
renal principal cell | 3 studies | 28% ± 8% | |
mucus secreting cell | 3 studies | 29% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 9370.00 | 1445 / 1445 | 100% | 29.94 | 183 / 183 |
brain | 100% | 10075.21 | 2639 / 2642 | 99% | 28.09 | 701 / 705 |
prostate | 100% | 8919.79 | 245 / 245 | 99% | 27.87 | 498 / 502 |
lung | 100% | 15129.05 | 578 / 578 | 99% | 25.87 | 1145 / 1155 |
kidney | 100% | 12589.29 | 89 / 89 | 99% | 39.64 | 893 / 901 |
breast | 100% | 10454.60 | 459 / 459 | 99% | 33.28 | 1104 / 1118 |
intestine | 100% | 9010.53 | 966 / 966 | 98% | 19.51 | 517 / 527 |
pancreas | 99% | 5666.46 | 325 / 328 | 99% | 24.45 | 176 / 178 |
stomach | 100% | 7393.71 | 359 / 359 | 98% | 22.99 | 279 / 286 |
bladder | 100% | 10173.19 | 21 / 21 | 97% | 18.69 | 490 / 504 |
thymus | 100% | 12763.92 | 653 / 653 | 96% | 39.05 | 583 / 605 |
ovary | 100% | 8018.86 | 180 / 180 | 96% | 16.74 | 412 / 430 |
uterus | 100% | 10317.93 | 170 / 170 | 95% | 16.93 | 437 / 459 |
adrenal gland | 100% | 10688.54 | 258 / 258 | 95% | 16.37 | 218 / 230 |
skin | 100% | 13480.79 | 1809 / 1809 | 94% | 19.12 | 445 / 472 |
liver | 100% | 8482.61 | 226 / 226 | 94% | 17.71 | 382 / 406 |
adipose | 100% | 10669.35 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 10688.69 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 8793.72 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 5527.98 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.75 | 1 / 1 |
heart | 99% | 7859.07 | 851 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 93% | 16.76 | 42 / 45 |
eye | 0% | 0 | 0 / 0 | 91% | 14.82 | 73 / 80 |
lymph node | 0% | 0 | 0 / 0 | 59% | 5.45 | 17 / 29 |
peripheral blood | 34% | 1377.94 | 314 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007266 | Biological process | Rho protein signal transduction |
GO_0051056 | Biological process | regulation of small GTPase mediated signal transduction |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005829 | Cellular component | cytosol |
GO_0016020 | Cellular component | membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0005515 | Molecular function | protein binding |
GO_0005096 | Molecular function | GTPase activator activity |
GO_0001664 | Molecular function | G protein-coupled receptor binding |
Gene name | ARHGEF12 |
Protein name | Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF) ARHGEF12 |
Synonyms | LARG KIAA0382 |
Description | FUNCTION: May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. . |
Accessions | ENST00000397843.7 [Q9NZN5-1] ENST00000532993.5 ENST00000356641.7 [Q9NZN5-2] Q9NZN5 E9PMR6 A0A2X0SFF5 |