ARHGAP26 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	32 studies	49% ± 21%	Explore
macrophage	19 studies	47% ± 24%	Explore
astrocyte	18 studies	56% ± 23%	Explore
microglial cell	16 studies	74% ± 13%	Explore
classical monocyte	14 studies	27% ± 10%	Explore
pericyte	13 studies	45% ± 17%	Explore
glutamatergic neuron	12 studies	64% ± 27%	Explore
smooth muscle cell	10 studies	33% ± 15%	Explore
myeloid cell	10 studies	52% ± 21%	Explore
endothelial cell of lymphatic vessel	10 studies	51% ± 24%	Explore
monocyte	9 studies	50% ± 29%	Explore
natural killer cell	9 studies	34% ± 17%	Explore
neutrophil	9 studies	37% ± 23%	Explore
GABAergic neuron	9 studies	57% ± 27%	Explore
fibroblast	9 studies	32% ± 12%	Explore
T cell	7 studies	33% ± 12%	Explore
CD8-positive, alpha-beta T cell	7 studies	31% ± 17%	Explore
adipocyte	7 studies	42% ± 12%	Explore
dendritic cell	7 studies	46% ± 17%	Explore
endothelial cell of artery	7 studies	37% ± 23%	Explore
vein endothelial cell	7 studies	38% ± 25%	Explore
neuron	6 studies	46% ± 18%	Explore
interneuron	6 studies	56% ± 23%	Explore
epithelial cell	6 studies	34% ± 14%	Explore
retina horizontal cell	6 studies	53% ± 25%	Explore
cardiac muscle cell	6 studies	58% ± 24%	Explore
CD16-positive, CD56-dim natural killer cell, human	5 studies	26% ± 17%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	30% ± 16%	Explore
capillary endothelial cell	5 studies	43% ± 22%	Explore
mast cell	5 studies	25% ± 17%	Explore
basal cell	5 studies	26% ± 12%	Explore
type II pneumocyte	5 studies	27% ± 2%	Explore
leukocyte	4 studies	62% ± 26%	Explore
non-classical monocyte	4 studies	27% ± 10%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	33% ± 19%	Explore
mature NK T cell	4 studies	28% ± 17%	Explore
granule cell	4 studies	49% ± 21%	Explore
lymphocyte	4 studies	48% ± 20%	Explore
amacrine cell	4 studies	60% ± 23%	Explore
oligodendrocyte precursor cell	4 studies	22% ± 6%	Explore
respiratory goblet cell	4 studies	50% ± 12%	Explore
oligodendrocyte	4 studies	31% ± 20%	Explore
endothelial cell of sinusoid	3 studies	41% ± 1%	Explore
conventional dendritic cell	3 studies	26% ± 14%	Explore
GABAergic interneuron	3 studies	48% ± 12%	Explore
CD4-positive, alpha-beta T cell	3 studies	36% ± 8%	Explore
endocardial cell	3 studies	51% ± 24%	Explore
mucosal invariant T cell	3 studies	31% ± 16%	Explore
GABAergic amacrine cell	3 studies	33% ± 13%	Explore
Mueller cell	3 studies	30% ± 9%	Explore
glycinergic amacrine cell	3 studies	39% ± 1%	Explore
retinal rod cell	3 studies	59% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	21% ± 7%	Explore
endothelial cell of vascular tree	3 studies	61% ± 13%	Explore
cholangiocyte	3 studies	56% ± 15%	Explore
hepatocyte	3 studies	52% ± 28%	Explore
connective tissue cell	3 studies	20% ± 3%	Explore
ependymal cell	3 studies	54% ± 15%	Explore
alveolar macrophage	3 studies	66% ± 11%	Explore
club cell	3 studies	32% ± 13%	Explore
goblet cell	3 studies	46% ± 33%	Explore
mesothelial cell	3 studies	36% ± 5%	Explore
mural cell	3 studies	49% ± 6%	Explore
mucus secreting cell	3 studies	64% ± 5%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	18 studies	42% ± 23%	Explore
lung	6 studies	30% ± 7%	Explore
heart	6 studies	44% ± 20%	Explore
eye	5 studies	36% ± 15%	Explore
peripheral blood	3 studies	24% ± 6%	Explore
adipose	3 studies	30% ± 8%	Explore
kidney	3 studies	20% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	100%	2668.72	965 / 966	100%	12.73	526 / 527
stomach	99%	2074.75	354 / 359	99%	12.09	283 / 286
brain	98%	4301.72	2600 / 2642	99%	9.52	698 / 705
lung	100%	4237.75	578 / 578	94%	8.06	1085 / 1155
esophagus	99%	2103.87	1424 / 1445	93%	10.32	170 / 183
prostate	99%	2124.67	242 / 245	91%	4.94	458 / 502
kidney	99%	1897.79	88 / 89	90%	10.08	808 / 901
thymus	100%	2791.33	652 / 653	88%	4.19	534 / 605
uterus	100%	2308.11	170 / 170	83%	6.66	383 / 459
breast	100%	3536.62	459 / 459	78%	4.79	877 / 1118
bladder	100%	1814.10	21 / 21	72%	5.72	362 / 504
skin	89%	1628.62	1604 / 1809	82%	4.24	387 / 472
pancreas	61%	632.65	199 / 328	95%	12.50	169 / 178
ovary	56%	644.20	101 / 180	96%	8.19	413 / 430
adrenal gland	73%	811.35	188 / 258	75%	7.51	172 / 230
liver	71%	693.27	161 / 226	49%	2.08	197 / 406
adipose	100%	3071.08	1204 / 1204	0%	0	0 / 0
spleen	100%	4410.74	241 / 241	0%	0	0 / 0
peripheral blood	100%	9909.38	928 / 929	0%	0	0 / 0
blood vessel	99%	2536.74	1323 / 1335	0%	0	0 / 0
heart	99%	3158.14	853 / 861	0%	0	0 / 0
muscle	96%	2119.32	768 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	87%	12.17	39 / 45
lymph node	0%	0	0 / 0	76%	3.48	22 / 29
eye	0%	0	0 / 0	6%	0.20	5 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0007165	Biological process	signal transduction
GO_0051056	Biological process	regulation of small GTPase mediated signal transduction
GO_0000423	Biological process	mitophagy
GO_0030036	Biological process	actin cytoskeleton organization
GO_0007399	Biological process	nervous system development
GO_0005575	Cellular component	cellular_component
GO_0010008	Cellular component	endosome membrane
GO_0005856	Cellular component	cytoskeleton
GO_0005829	Cellular component	cytosol
GO_0005739	Cellular component	mitochondrion
GO_0005925	Cellular component	focal adhesion
GO_0030674	Molecular function	protein-macromolecule adaptor activity
GO_0005515	Molecular function	protein binding
GO_0005543	Molecular function	phospholipid binding
GO_0005096	Molecular function	GTPase activator activity

IV. Literature review

[source]

Gene name	ARHGAP26
Protein name	Rho GTPase activating protein 26 isoform 2 Rho GTPase-activating protein 26 (Rho-type GTPase-activating protein 26) Rho GTPase activating protein 26 variant 3 Rho GTPase activating protein 26 Rho GTPase-activating protein 26 (GTPase regulator associated with focal adhesion kinase) (GRAF1) (Oligophrenin-1-like protein) (Rho-type GTPase-activating protein 26)
Synonyms	OPHN1L KIAA0621 GRAF
Description	FUNCTION: GTPase-activating protein for RHOA and CDC42. .; FUNCTION: [Isoform 2]: Associates with MICAL1 on the endosomal membrane to promote Rab8-Rab10-dependent tubule extension. After dissociation of MICAL1, recruits WDR44 which connects the endoplasmic reticulum (ER) with the endosomal tubule, thereby participating in the export of a subset of neosynthesized proteins. .
Accessions	A0A2X0SSF1 H7C1J1 ENST00000443045.1 ENST00000451259.1 ENST00000425417.2 ENST00000443674.5 H0Y4P9 H7BZZ0 Q9UNA1 D9ZGG7 H7C205 A0A2R8YGB3 A0A2R8YDK5 H7BZE1 ENST00000419676.5 ENST00000645722.2 [Q9UNA1-2] ENST00000418236.5 A0A0S2Z536 ENST00000424007.1 H0Y835 ENST00000421521.5 H7C3P8 ENST00000274498.9 [Q9UNA1-1] ENST00000469131.6 ENST00000642734.1 A0A2R8Y5C0 ENST00000475287.2 C9J6V4 A0A0S2Z508

ARHGAP26 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review