ANKRD28 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	29 studies	28% ± 14%	Explore
mast cell	27 studies	41% ± 16%	Explore
plasma cell	18 studies	47% ± 18%	Explore
oligodendrocyte	16 studies	45% ± 17%	Explore
astrocyte	16 studies	35% ± 15%	Explore
fibroblast	15 studies	24% ± 8%	Explore
oligodendrocyte precursor cell	14 studies	56% ± 21%	Explore
natural killer cell	12 studies	22% ± 7%	Explore
glutamatergic neuron	11 studies	48% ± 24%	Explore
T cell	10 studies	30% ± 7%	Explore
ciliated cell	9 studies	29% ± 10%	Explore
GABAergic neuron	9 studies	54% ± 20%	Explore
CD4-positive, alpha-beta T cell	9 studies	25% ± 5%	Explore
hematopoietic stem cell	9 studies	51% ± 15%	Explore
endothelial cell of vascular tree	9 studies	32% ± 15%	Explore
epithelial cell	8 studies	37% ± 20%	Explore
CD8-positive, alpha-beta T cell	8 studies	18% ± 4%	Explore
type II pneumocyte	7 studies	39% ± 12%	Explore
classical monocyte	7 studies	29% ± 15%	Explore
mature NK T cell	7 studies	22% ± 6%	Explore
macrophage	7 studies	25% ± 12%	Explore
adipocyte	7 studies	34% ± 9%	Explore
plasmablast	6 studies	37% ± 12%	Explore
interneuron	6 studies	55% ± 19%	Explore
pericyte	6 studies	29% ± 13%	Explore
smooth muscle cell	6 studies	18% ± 1%	Explore
connective tissue cell	6 studies	19% ± 2%	Explore
B cell	6 studies	28% ± 14%	Explore
retinal cone cell	6 studies	44% ± 14%	Explore
alveolar macrophage	6 studies	31% ± 14%	Explore
Mueller cell	6 studies	42% ± 23%	Explore
type I pneumocyte	6 studies	28% ± 11%	Explore
gamma-delta T cell	6 studies	29% ± 13%	Explore
basal cell	6 studies	32% ± 23%	Explore
dendritic cell	5 studies	21% ± 6%	Explore
hematopoietic precursor cell	5 studies	60% ± 22%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	21% ± 4%	Explore
conventional dendritic cell	5 studies	33% ± 18%	Explore
neuron	5 studies	49% ± 14%	Explore
IgA plasma cell	5 studies	57% ± 18%	Explore
IgG plasma cell	5 studies	47% ± 9%	Explore
lymphocyte	5 studies	31% ± 12%	Explore
myeloid cell	5 studies	30% ± 5%	Explore
amacrine cell	5 studies	43% ± 18%	Explore
innate lymphoid cell	5 studies	33% ± 17%	Explore
endothelial cell of lymphatic vessel	5 studies	22% ± 6%	Explore
club cell	5 studies	32% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	23% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	4 studies	18% ± 2%	Explore
granule cell	4 studies	44% ± 4%	Explore
microglial cell	4 studies	32% ± 13%	Explore
cardiac muscle cell	4 studies	19% ± 1%	Explore
retinal rod cell	4 studies	31% ± 9%	Explore
CD4-positive helper T cell	4 studies	31% ± 14%	Explore
capillary endothelial cell	4 studies	24% ± 6%	Explore
vein endothelial cell	4 studies	41% ± 24%	Explore
granulocyte	4 studies	35% ± 14%	Explore
respiratory goblet cell	4 studies	33% ± 11%	Explore
melanocyte	4 studies	42% ± 23%	Explore
mononuclear phagocyte	3 studies	21% ± 2%	Explore
GABAergic interneuron	3 studies	44% ± 7%	Explore
progenitor cell	3 studies	35% ± 6%	Explore
common myeloid progenitor	3 studies	47% ± 27%	Explore
pro-B cell	3 studies	17% ± 2%	Explore
retinal pigment epithelial cell	3 studies	34% ± 21%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	30% ± 4%	Explore
mucosal invariant T cell	3 studies	24% ± 4%	Explore
GABAergic amacrine cell	3 studies	53% ± 22%	Explore
glycinergic amacrine cell	3 studies	34% ± 14%	Explore
retina horizontal cell	3 studies	42% ± 12%	Explore
endothelial cell of artery	3 studies	26% ± 6%	Explore
hepatocyte	3 studies	59% ± 21%	Explore
ependymal cell	3 studies	48% ± 12%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	47% ± 23%	Explore
monocyte	3 studies	36% ± 15%	Explore
group 3 innate lymphoid cell	3 studies	27% ± 12%	Explore
Schwann cell	3 studies	34% ± 20%	Explore
goblet cell	3 studies	38% ± 25%	Explore
transit amplifying cell	3 studies	44% ± 35%	Explore
leukocyte	3 studies	26% ± 6%	Explore
T-helper 17 cell	3 studies	45% ± 21%	Explore
platelet	3 studies	19% ± 2%	Explore
mucus secreting cell	3 studies	24% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	16 studies	44% ± 20%	Explore
lung	8 studies	28% ± 8%	Explore
eye	6 studies	35% ± 16%	Explore
peripheral blood	4 studies	25% ± 11%	Explore
intestine	4 studies	31% ± 16%	Explore
liver	3 studies	32% ± 15%	Explore
adipose	3 studies	33% ± 11%	Explore
kidney	3 studies	24% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2573.54	1445 / 1445	100%	16.07	183 / 183
breast	100%	4454.17	459 / 459	100%	21.61	1117 / 1118
ovary	100%	4563.00	180 / 180	100%	13.14	429 / 430
bladder	100%	2581.10	21 / 21	100%	12.63	502 / 504
brain	100%	3934.90	2636 / 2642	100%	18.86	703 / 705
lung	100%	3155.63	576 / 578	100%	13.49	1153 / 1155
intestine	100%	3531.66	966 / 966	99%	13.02	524 / 527
prostate	100%	2736.98	244 / 245	100%	12.69	500 / 502
thymus	100%	3809.93	653 / 653	99%	16.40	600 / 605
pancreas	100%	2688.13	327 / 328	99%	12.44	177 / 178
skin	100%	6504.70	1808 / 1809	99%	35.69	468 / 472
stomach	100%	2339.79	359 / 359	99%	13.49	283 / 286
uterus	100%	3398.55	170 / 170	98%	12.46	452 / 459
kidney	100%	2296.71	89 / 89	97%	10.88	872 / 901
liver	100%	2088.32	226 / 226	94%	7.79	383 / 406
adrenal gland	100%	2654.04	257 / 258	83%	5.51	191 / 230
adipose	100%	4388.68	1204 / 1204	0%	0	0 / 0
muscle	100%	6411.98	803 / 803	0%	0	0 / 0
spleen	100%	2566.74	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	4.87	1 / 1
blood vessel	100%	3414.28	1334 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	15.14	44 / 45
lymph node	0%	0	0 / 0	93%	7.57	27 / 29
eye	0%	0	0 / 0	85%	9.87	68 / 80
heart	78%	1103.58	673 / 861	0%	0	0 / 0
peripheral blood	48%	1675.98	450 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	ANKRD28
Protein name	Ankyrin repeat domain 28, isoform CRA_f (cDNA FLJ57080, highly similar to Ankyrin repeat domain-containing protein 28) Ankyrin repeat domain 28 Ankyrin repeat domain 28 (cDNA FLJ54784, highly similar to Ankyrin repeat domain-containing protein 28) Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (PP6-ARS-A) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A) (Ankyrin repeat domain-containing protein 28) (Phosphatase interactor targeting protein hnRNP K) (PITK)
Synonyms	hCG_1811142 KIAA0379
Description	FUNCTION: Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation. .
Accessions	B4DS25 B4DIW9 ENST00000624145.3 [O15084-2] ENST00000412318.5 [O15084-3] ENST00000451422.1 F8WDU2 ENST00000439830.5 O15084 ENST00000683139.1 [O15084-4] ENST00000399451.6 [O15084-3]

GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005515	Molecular function	protein binding

ANKRD28 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review