AGTRAP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008217Biological processregulation of blood pressure
GO_0038166Biological processangiotensin-activated signaling pathway
GO_0001666Biological processresponse to hypoxia
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0000139Cellular componentGolgi membrane
GO_0005938Cellular componentcell cortex
GO_0005794Cellular componentGolgi apparatus
GO_0005886Cellular componentplasma membrane
GO_0030659Cellular componentcytoplasmic vesicle membrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005515Molecular functionprotein binding
GO_0004945Molecular functionangiotensin type II receptor activity

IV. Literature review

[source]
Gene nameAGTRAP
Protein nameType-1 angiotensin II receptor-associated protein (AT1 receptor-associated protein)
Angiotensin II receptor associated protein
SynonymsATRAP
DescriptionFUNCTION: Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. .

AccessionsENST00000376629.8 [Q6RW13-2]
ENST00000510878.1
D6RB40
ENST00000314340.10 [Q6RW13-1]
ENST00000400895.6 [Q6RW13-3]
ENST00000452018.6 [Q6RW13-5]
ENST00000376627.6
ENST00000376637.7 [Q6RW13-4]
X6R9H3
ENST00000476512.5
Q6RW13
D6RBK6