double-strand break repair via classical nonhomologous end joining

I. Literature review

[source]
Namedouble-strand break repair via classical nonhomologous end joining
IDGO_0097680
collection_id

Biological process

Exact synonym

canonical nonhomologous end joining

Description

An instance of double-strand break repair via nonhomologous end joining that requires a number of factors important for V(D)J recombination, including the KU70/80 heterodimer (KU), XRCC4, ligase IV, and DNA-PKcs in mammals. It does not produce translocations (as opposed to the alternative nonhomologous end joining).

Related synonym

C-NHEJ

External URL
Genes