response to cholesterol

I. Involved cell types

Genes
Cell types
No. of supported studies
Group 1
CYP8B1
hepatocyte
3 studies
Group 2
TGFB1SMAD2CCL3TGFBR2
myeloid cell
5 studies
Group 3
ABCA2
oligodendrocyte
26 studies
Group 4
TGFBR1
microglial cellmacrophage
34 studies
Group 5
PMVK
epithelial cellmyeloid cellB cellneuron
38 studies

II. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1CCL3-CCR5CCL3_HUMAN - CCR5_HUMANLigand-ReceptorSignaling by Chemokines
2TGFB1-ACVR1+TGFBR2TGFB1_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
3TGFB1-TGFBR1+TGFBR2TGFB1_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor

III. Literature review

[source]
Nameresponse to cholesterol
IDGO_0070723
collection_id

Biological process

Description

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.

External URL
Genes
F7CCL3PMVKTGFB1ABCA2CCR5TGFBR1TGFBR2CYP8B1SMAD2