somatic stem cell division

I. Involved cell types

Genes
Cell types
No. of supported studies
Group 1
HOXB4
neuronepithelial cellglial cell
6 studies
Group 2
CDKN2AZFP36L2
epithelial cell
9 studies
Group 3
BMI1
epithelial cellneuronsecretory cell
4 studies
Group 4
NOTCH1TGFB2
glial cell
5 studies

II. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1WNT3A-FZD7+LRP5WNT3A_HUMAN - Ligand-ReceptorSignaling by WNT
2WNT3A-FZD7+LRP6WNT3A_HUMAN - Ligand-ReceptorSignaling by WNT
3WNT7A-FZD7+LRP5WNT7A_HUMAN - Ligand-ReceptorSignaling by WNT
4WNT7A-FZD7+LRP6WNT7A_HUMAN - Ligand-ReceptorSignaling by WNT

III. Literature review

[source]
Namesomatic stem cell division
IDGO_0048103
collection_id

Biological process

Exact synonym

somatic stem cell renewal

Description

The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.

External URL
Genes
NOTCH1ZFP36L2FZD7WNT7ATGFB2WNT3AHOXB4BMI1CDKN2A