Derlin-1 retrotranslocation complex

I. Literature review

[source]
NameDerlin-1 retrotranslocation complex
IDGO_0036513
collection_id

Cellular component

Exact synonym

Derlin-1 complex, Derlin-1 protein dislocation complex, Derlin-1 retro-translocation complex, Derlin-1 retrotranslocon, ERAD protein dislocation complex

Description

A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel.

Comment

The Derlin-1 retrotranslocation complex is likely to assemble in steps, thereby containing different components at different stages of the retrotranslocation process.

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Genes