interleukin-18-mediated signaling pathway

I. Involved cell types

Genes
Cell types
No. of supported studies
Group 1
IL18RAPPIK3R1
natural killer cellCD16-negative, CD56-bright natural killer cell, human
9 studies
Group 2
PDGFB
endothelial cellmacrophageSchwann cellmicroglial cell
13 studies
Group 3
AKT1IL18
epithelial cell
7 studies
Group 4
IL18R1
mast cell
20 studies

II. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1IL18-IL18R1+IL18RAPIL18_HUMAN - Ligand-ReceptorSignaling by Interleukin

III. Literature review

[source]
Nameinterleukin-18-mediated signaling pathway
IDGO_0035655
collection_id

Biological process

Exact synonym

interleukin-18-mediated signalling pathway

Description

The series of molecular signals initiated by interleukin-18 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.

External URL
Genes
IL18PIK3R1AKT1IL18R1IL18RAPPDGFB