negative regulation of platelet activation

I. Involved cell types

Genes
Cell types
No. of supported studies
Group 1
C1QTNF1APOE
connective tissue cell
17 studies
Group 2
PDGFBTHBD
endothelial cell
5 studies
Group 3
F2
hepatocyte
6 studies
Group 4
PDGFA
myeloid cellpericyteepithelial cell
49 studies
Group 5
PDGFRA
fibroblastoligodendrocyte precursor cellconnective tissue cell
61 studies

II. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1F2-THBDTHRB_HUMAN - TRBM_HUMANLigand-ReceptorAdhesion by Prothrombin
2PDGFA-PDGFRAPDGFA_HUMAN - PGFRA_HUMANLigand-ReceptorSignaling by Platelet-derived growth factor
3PDGFB-PDGFRAPDGFB_HUMAN - PGFRA_HUMANLigand-ReceptorSignaling by Platelet-derived growth factor
4PDGFB-PDGFRA+PDGFRBPDGFB_HUMAN - Ligand-ReceptorSignaling by Platelet-derived growth factor

III. Literature review

[source]
Namenegative regulation of platelet activation
IDGO_0010544
collection_id

Biological process

Description

Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.

External URL
Genes
C1QTNF1APOEF2PDGFAPDGFBPDGFRATHBDNOS3