Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 27 studies | 38% ± 14% | |
macrophage | 17 studies | 28% ± 11% | |
endothelial cell of lymphatic vessel | 17 studies | 40% ± 20% | |
endothelial cell of artery | 11 studies | 35% ± 13% | |
capillary endothelial cell | 11 studies | 37% ± 10% | |
classical monocyte | 11 studies | 28% ± 9% | |
vein endothelial cell | 11 studies | 42% ± 17% | |
endothelial cell of vascular tree | 10 studies | 45% ± 17% | |
dendritic cell | 8 studies | 26% ± 10% | |
plasmacytoid dendritic cell | 8 studies | 26% ± 8% | |
conventional dendritic cell | 8 studies | 20% ± 4% | |
monocyte | 7 studies | 29% ± 13% | |
myeloid cell | 5 studies | 20% ± 2% | |
alveolar macrophage | 4 studies | 25% ± 6% | |
non-classical monocyte | 4 studies | 17% ± 0% | |
pericyte | 3 studies | 18% ± 2% | |
mononuclear phagocyte | 3 studies | 19% ± 4% | |
intermediate monocyte | 3 studies | 32% ± 18% | |
smooth muscle cell | 3 studies | 21% ± 2% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 3 studies | 21% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 97% | 4493.89 | 1398 / 1445 | 97% | 120.02 | 177 / 183 |
lung | 100% | 11450.60 | 578 / 578 | 93% | 59.74 | 1076 / 1155 |
thymus | 99% | 7707.57 | 647 / 653 | 90% | 30.00 | 543 / 605 |
breast | 98% | 5103.78 | 452 / 459 | 89% | 26.95 | 994 / 1118 |
bladder | 95% | 2466.19 | 20 / 21 | 86% | 67.77 | 431 / 504 |
stomach | 97% | 4662.32 | 347 / 359 | 79% | 22.51 | 226 / 286 |
intestine | 83% | 2982.21 | 806 / 966 | 71% | 17.10 | 373 / 527 |
uterus | 77% | 2245.54 | 131 / 170 | 76% | 73.29 | 347 / 459 |
kidney | 69% | 1926.29 | 61 / 89 | 84% | 31.91 | 757 / 901 |
skin | 81% | 9733.72 | 1467 / 1809 | 67% | 21.85 | 314 / 472 |
adrenal gland | 74% | 1839.19 | 191 / 258 | 70% | 23.26 | 162 / 230 |
prostate | 58% | 1386.36 | 142 / 245 | 72% | 15.29 | 360 / 502 |
pancreas | 19% | 307.75 | 61 / 328 | 94% | 40.91 | 168 / 178 |
tonsil | 0% | 0 | 0 / 0 | 100% | 91.40 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 16.61 | 1 / 1 |
adipose | 99% | 8869.76 | 1197 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 9001.46 | 1326 / 1335 | 0% | 0 | 0 / 0 |
spleen | 99% | 5880.62 | 239 / 241 | 0% | 0 | 0 / 0 |
heart | 94% | 3416.08 | 812 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 69% | 13.78 | 20 / 29 |
ovary | 37% | 937.48 | 67 / 180 | 30% | 5.81 | 131 / 430 |
peripheral blood | 67% | 2618.76 | 622 / 929 | 0% | 0 | 0 / 0 |
muscle | 59% | 3679.84 | 472 / 803 | 0% | 0 | 0 / 0 |
liver | 24% | 522.63 | 55 / 226 | 33% | 6.45 | 135 / 406 |
brain | 4% | 89.51 | 116 / 2642 | 27% | 5.56 | 190 / 705 |
eye | 0% | 0 | 0 / 0 | 11% | 2.09 | 9 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0010544 | Biological process | negative regulation of platelet activation |
GO_0010165 | Biological process | response to X-ray |
GO_0051918 | Biological process | negative regulation of fibrinolysis |
GO_0072377 | Biological process | blood coagulation, common pathway |
GO_0007596 | Biological process | blood coagulation |
GO_0007565 | Biological process | female pregnancy |
GO_0031638 | Biological process | zymogen activation |
GO_0051591 | Biological process | response to cAMP |
GO_0006508 | Biological process | proteolysis |
GO_0030195 | Biological process | negative regulation of blood coagulation |
GO_0032496 | Biological process | response to lipopolysaccharide |
GO_0005615 | Cellular component | extracellular space |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0009986 | Cellular component | cell surface |
GO_0005774 | Cellular component | vacuolar membrane |
GO_1905370 | Cellular component | serine-type endopeptidase complex |
GO_0016327 | Cellular component | apicolateral plasma membrane |
GO_0038023 | Molecular function | signaling receptor activity |
GO_0004888 | Molecular function | transmembrane signaling receptor activity |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | THBD |
Protein name | Thrombomodulin (TM) (Fetomodulin) (CD antigen CD141) |
Synonyms | THRM |
Description | FUNCTION: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. |
Accessions | ENST00000377103.3 P07204 |