WDR74 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0016070Biological processRNA metabolic process
GO_0042273Biological processribosomal large subunit biogenesis
GO_0001825Biological processblastocyst formation
GO_0006364Biological processrRNA processing
GO_0030687Cellular componentpreribosome, large subunit precursor
GO_0005730Cellular componentnucleolus
GO_0005654Cellular componentnucleoplasm
GO_0000176Cellular componentnuclear exosome (RNase complex)
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameWDR74
Protein nameWD repeat domain 74
WD repeat-containing protein 74 (NOP seven-associated protein 1)
SynonymsNSA1
DescriptionFUNCTION: Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit . Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL . Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development (By similarity). .

AccessionsENST00000525239.5 [Q6RFH5-1]
ENST00000529106.5 [Q6RFH5-1]
ENST00000278856.9 [Q6RFH5-1]
F5GYL6
ENST00000525752.5
ENST00000536401.1
E9PS41
ENST00000538098.2
Q6RFH5
ENST00000311713.11 [Q6RFH5-2]
H0YFP2