Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1055.15 | 1445 / 1445 | 100% | 15.42 | 183 / 183 |
| ovary | 100% | 1382.02 | 180 / 180 | 100% | 23.05 | 430 / 430 |
| pancreas | 100% | 932.87 | 328 / 328 | 100% | 14.14 | 178 / 178 |
| prostate | 100% | 1115.36 | 245 / 245 | 100% | 15.89 | 502 / 502 |
| skin | 100% | 1563.92 | 1809 / 1809 | 100% | 20.20 | 472 / 472 |
| stomach | 100% | 953.47 | 359 / 359 | 100% | 18.95 | 286 / 286 |
| lung | 100% | 934.71 | 577 / 578 | 100% | 16.92 | 1155 / 1155 |
| intestine | 100% | 1032.70 | 966 / 966 | 100% | 21.40 | 526 / 527 |
| liver | 100% | 766.48 | 226 / 226 | 100% | 12.20 | 405 / 406 |
| breast | 100% | 1170.14 | 459 / 459 | 100% | 14.24 | 1114 / 1118 |
| bladder | 100% | 1123.29 | 21 / 21 | 100% | 20.47 | 502 / 504 |
| uterus | 100% | 1166.51 | 170 / 170 | 100% | 18.57 | 457 / 459 |
| thymus | 100% | 998.35 | 652 / 653 | 100% | 15.51 | 603 / 605 |
| kidney | 100% | 827.00 | 89 / 89 | 99% | 11.76 | 896 / 901 |
| brain | 99% | 746.08 | 2608 / 2642 | 100% | 16.63 | 705 / 705 |
| adrenal gland | 100% | 1056.35 | 258 / 258 | 94% | 9.16 | 216 / 230 |
| adipose | 100% | 1099.64 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 26.70 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 25.70 | 29 / 29 |
| muscle | 100% | 1577.59 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1255.68 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 18.25 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 13.28 | 1 / 1 |
| blood vessel | 100% | 999.01 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 97% | 597.53 | 834 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 95% | 765.87 | 881 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0016070 | Biological process | RNA metabolic process |
| GO_0042273 | Biological process | ribosomal large subunit biogenesis |
| GO_0001825 | Biological process | blastocyst formation |
| GO_0006364 | Biological process | rRNA processing |
| GO_0030687 | Cellular component | preribosome, large subunit precursor |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0000176 | Cellular component | nuclear exosome (RNase complex) |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| Gene name | WDR74 |
| Protein name | WD repeat domain 74 WD repeat-containing protein 74 (NOP seven-associated protein 1) |
| Synonyms | NSA1 |
| Description | FUNCTION: Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit . Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL . Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development (By similarity). . |
| Accessions | ENST00000525239.5 [Q6RFH5-1] ENST00000529106.5 [Q6RFH5-1] ENST00000278856.9 [Q6RFH5-1] F5GYL6 ENST00000525752.5 ENST00000536401.1 E9PS41 ENST00000538098.2 Q6RFH5 ENST00000311713.11 [Q6RFH5-2] H0YFP2 |